The chance to forge new ties between Uzbekistan and Turkiye emerged in 2016 with the change of leadership, following about 20 years of ups and downs. The strained relations were due to several political hiccups like Turkiye’s asylum to Uzbek dissidents, Currencycrisis of Turkiye, banning of Gulen schools and the Andijan event. This study focuses on the relations between Turkiye and Uzbekistan in the post-Karimov period. The focus will be on the development of political relations and the opening of new ventures due to current geopolitics in Turkiye-Uzbekistan relationship dynamics. The geo-strategic position of Turkey enables it to become transit hub as it is situated in between energy scarce European market and energy rich countries on the other side. Uzbekistan needs to diversify its export partners where Turkey as a transit hub can play crucial role. The construction of trans-Caspian pipeline to move energy from Central Asia and the Caspian sea region to Turkey and for European markets, is primary strategic goal. Both sides needed constructive attitudes to further the relations. There have been a number of high-level political visits and signing of important strategic cooperation agreements. Both heads of the state frequently refer to Turkic-Islamic symbols of shared identity while addressing their relationship. The bilateral relations have been improving in all the fields majorly in trade. To deepen and strengthen the relations further the trade goal of $10 billion is set. In 2022, the relationship was elevated to a "comprehensive strategic partnership level".