In this work, we consider a class of neutral stochastic integro-differential equations driven by Wiener process and fractional Brownian motion with impulses effects. This paper deals with the global attractiveness and quasiinvariant sets for neutral stochastic integro-differential equations driven by Wiener process and fractional Brownian motion with impulses effects in Hilbert spaces. We use new integral inequalities combined with theoriesof resolvent operators to establish a set of sufficient conditions for the exponential p-stability of the mild solution of the considered equations. An example is presented to demonstrate the obtained theory.