YouTube videos about intramuscular injection with the Z technique were evaluated for content, quality and reliability. A search of YouTube was made on 13 November 2023 using the keywords of “Z technique” and “intramuscular injection”. 40 videos that fulfilled the inclusion criteria were assessed for usefulness using the Z Technique Intramuscular Injection Administration Checklist (ZIAC), reliability using the Quality Criteria for Consumer Health (DISCERN), and quality using the Global Quality Scale (GQS) scores. Most of the videos used in the study belonged to individual content producers. The videos were determined to be of medium quality, and reliability, but their usefulness was not at the desired level based on their ZIAC, DISCERN, and GQS scores (respectively; 16.92±2.72; 2.92±0.763; 3.03±0.77). Furthermore, the videos' usefulness (ZIAC), reliability (DISCERN), and quality (GQS) scores all showed a strong positive correlation. It was determined that the dorsogluteal region was preferred in 48.1% of the videos (n=13), and the region was determined correctly in 67.5% of the videos (n=27). To provide the most reliable information to healthcare professionals, particularly nurses, it is recommended that expert nurses and educators create qualified videos about the use of intramuscular injection with the Z technique and share them on YouTube.