THEOBALD SMITH (1859-1934), PIONEER AMERICAN MICROBIOLOGIST CLAUDE E. DOLMAN* Philip and Theresia Schmitt, newly married, arrived at Albany, New York, from a troubled Germany about 130 years ago, after an 8 weeks' crossing from Antwerp. They each had a sister living in Albany, but otherwise knew nobody, nor any word of English, and possessed only common skills—he as journeyman tailor, she as housekeeper. Albany had already too many tailors to meet the periodic demands of assemblymen and their wives for frock coats and new gowns, while Theresia's housekeeping talents were dedicated to her husband, the two children who arrived soon enough, and several boarders who helped to pay off the mortgage. The first child, Bertha, married a carpenter and died at 34 from an ectopic gestation, leaving three small Murphys to an uncertain future. The second child was christened in the Catholic faith— his father being Protestant. The given name, Theobald, alone sets this Smith apart. Jacob Theobald was a fellow immigrant and family benefactor . The boy temporarily adopted the name Jacob, so that he appeared in early school lists as T. J. Schmitt. His high school essays were signed Theobald J. Smith. At university he jettisoned the/ and also the Catholic faith, after being denounced from the pulpit by his parish priest for not going to confession. The Formative Years (1874-1883) The youth's academic record at Albany High School—then a remarkably progressive yet demanding institution—was impressive. Never Address presented September 17, 1980, at ajoint annual meeting of the Canadian and Australian Medical Associations, Vancouver, British Columbia, Canada. The author is indebted to Philip H. Smith, son and executor of Dr. Theobald Smith, for access to various family papers, and to the Hannah Foundation for the History of Medicine for their sponsorship and a grant-in-aid toward a full-length biography of Theobald Smith. *Professor emeritus of microbiology, University of British Columbia, Vancouver, British Columbia V6T 1W5.© 1982 by The University of Chicago. All rights reserved. 003 1 -5982/82/2503-0258$0 1 .00 Perspectives in Biology and Medicine, 25, 3 · Spring 1982 | 417 late or absent in 4 years, he always headed his class, and in 1 876—when Robert Koch published his classic report on The Aetiology of Anthrax— Theobald Smith was named valedictorian. As secretary and president of the Philologians, the school's debating society, he learned the techniques of argument, the appraisal of evidence, the value of vocabulary, and the diversity of topics that the human mind can contemplate and sometimes comprehend. With special friends he tramped the countryside, often picking berries, occasionally filching apples, always admiring nature, whether as wild flower, distant hills, or glowing summer sun; boating and fishing on the Hudson River and its tributary, the Normans Kill; and playing the grand piano at home or the organ in whatever church allowed it. He earned pocket money and helped liquidate the debt on the piano by giving music lessons and keeping the books for a retail tailor. He also looked after the garden and was the household handyman. Spare time was devoted to study—at weekends in the state library; at night, around the kitchen stove or in his bedroom, by candlelight. Albany's harsh climate generated Theobald Smith's daily weather observations , so that he became an expert amateur meteorologist. Similarly, his lifelong frugalities can be traced to the family's early penury. His thriftiness in adulthood has been made legendary by persons as ignorant of the young boy's chapped hands and mud-caked feet and his agonized two-day search for a mislaid quarter as of his charitable contributions— for the victims of the Johnstown flood, for the purchase of his primary school teacher's gravestone, or the forgetting of a substantial loan to his laboratory assistant [I]. At Cornell University, then recently founded and full of pioneering excitements, such as academic utilitarianism and coeducation, Smith maintained his excellent record. He gained a free-tuition scholarship and resolved not to specialize. "My ideas of an education," he noted as a sophomore, "are broad, liberal, of the widest kind." Accordingly, he enrolled in courses ranging from economic geology to Faust, from the...