We sought to understand how the mental state of religious queer individuals is affected by religious marginalization and queer identity. Using a multi-method approach, we analyzed data from 626 participants to assess how a queer status affected psychological distress and life satisfaction, the mediating effect of strength of faith on the relationship between the queer status and life satisfaction, and the moderating effect of experiences with marginalization on the relationship between the strength of faith, psychological distress, and life satisfaction. Queer status was found to have a significant impact on queer individuals’ psychological wellness and life satisfaction. Marginalization experiences decreased psychological wellness and life satisfaction. Our qualitative analyses add to these results, describing the weaponization of queer identity in religious settings. These results can be attributed to the strong main effects of queer status and strength of faith on psychological distress and life satisfaction rather than tertiary variables.