Objective: Home Blood Pressure Telemonitoring (HBPT) has been proposed to improve blood pressure (BP) control, and efficient care delivery in patients with hypertension. Its adoption in GP practices however remains low. In this pilot study we evaluated barriers and facilitators for successful implementation, patient satisfaction, clinical effectiveness, and efficiency for a HBPT project in Dutch GP practices by means of the Quadruple Aim Model. Design and method: GP practices included patients with hypertension that were part of their regular cardiovascular disease program. The hospital would initially support the HBPT program followed by a period in which the GP practices were primarily responsible for the telemonitoring (figure 1, procedures A and B). We conducted semi-structured interviews at 3- and 6-months (figure 2) to identify barriers and facilitators for successful implementation. Patient satisfaction was measured with Telehealth Usability (TUQ) - and MHealth App Usability (MAUQ) Questionnaires. A Systolic Blood Pressure Intervention Trial (SPRINT) -protocol BP measurement was performed after the pilot project to assess clinical effectiveness. Efficiency data were collected on the number of registered consultations during the 6-month project. Results: Three GP practices included 19 patients. Barriers for implementation (table 1) were a lack of a reimbursement structure, lack of information technology system integration and increased experienced workload when using HBPT. Facilitators (table 1) included the positive effects on BP control, increased sense of safety for patient and care provider, and increased disease-insight. Median satisfaction scores for TUQ and MAUQ questionnaires (scale 1-7) were 6 (IQR 5-6) and 6 (IQR 5-7). At baseline, 16% of the patients had a BP <140/90 mmHg. Based on the performed SPRINT measurements, 68% had a well-controlled BP (<140/90 mmHg) after 6 months. Average BP improved from 151/89 mmHg to 132/81 mmHg (p=0.0004). On average, one monthly contact moment related to hypertension between patient and GP practice was registered. Conclusions: We found positive results following the introduction of HBPT in GP practices on clinical outcomes and patients’ satisfaction, however for large-scale implementation improvements with regards to organizational efficiency and a clear reimbursement structure are needed.