The 3D Printing technique has been globally used in bone tissue engineering as well as biomedical applications owing to its advantage of the quick, precise and controllable freeform fabrication process. In this printing technique, anatomical information of defected parts is gathered and converted into a CAD model, which is translated into Printer language. Among different additive manufacturing methods, direct ink writing (DIW) has gained attention among the academic and industrial communities due to its ability to build up the structure on any surface without any masking or tooling as well as no powder bed and the expensive laser source is required for printing. Bio-ceramics are utilized in biomedical fields because of the properties like high stiffness, bioactive, biocompatibility, osteoconductivity, therefore helping for bone regeneration and growing in vivo and in vitro environment. This paper reviews the current status and case studies involved in DIW of Bio-ceramic/composite for different biomedical applications.