Expanding Frontiers Research Articles

Mid-infrared trace detection with parts-per-quadrillion quantitation accuracy: Expanding frontiers of radiocarbon sensing

Detection sensitivity is a critical characteristic to consider during selection of spectroscopic techniques. However, high sensitivity alone is insufficient for spectroscopic measurements in spectrally congested regions. Two-color cavity ringdown spectroscopy (2C-CRDS), based on intra-cavity pump-probe detection, simultaneously achieves high detection sensitivity and selectivity. This combination enables mid-infrared detection of radiocarbon dioxide ([Formula: see text]CO[Formula: see text]) molecules in room-temperature CO[Formula: see text] samples, with 1.4 parts-per-quadrillion (ppq, 10[Formula: see text]) sensitivity (average measurement precision) and 4.6-ppq quantitation accuracy (average calibrated measurement error for 21 samples from four separate trials) demonstrated on samples with [Formula: see text]C/C up to [Formula: see text]1.5[Formula: see text] natural abundance ([Formula: see text]1,800 ppq). These highly reproducible measurements, which are the most sensitive and quantitatively accurate in the mid-infrared, are accomplished despite the presence of orders-of-magnitude stronger, one-photon signals from other CO[Formula: see text] isotopologues. This is a major achievement in laser spectroscopy. A room-temperature-operated, compact, and low-cost 2C-CRDS sensor for [Formula: see text]CO[Formula: see text] benefits a wide range of scientific fields that utilize [Formula: see text]C for dating and isotope tracing, most notably atmospheric [Formula: see text]CO[Formula: see text] monitoring to track CO[Formula: see text] emissions from fossil fuels. The 2C-CRDS technique significantly enhances the general utility of high-resolution mid-infrared detection for analytical measurements and fundamental chemical dynamics studies.

Giusi Russo. Women, Empires, and Body Politics at the United Nations, 1946–1975. [Expanding Frontiers: Interdisciplinary Approaches to Studies of Women, Gender, and Sexuality.] University of Nebraska Press, Lincoln (NE) 2023. xiii, 287 pp. Ill. $99.00. (Paper, E-book: $30.00.)

Giusi Russo. Women, Empires, and Body Politics at the United Nations, 1946–1975. [Expanding Frontiers: Interdisciplinary Approaches to Studies of Women, Gender, and Sexuality.] University of Nebraska Press, Lincoln (NE) 2023. xiii, 287 pp. Ill. $99.00. (Paper, E-book: $30.00.)

Equinox 2022: The Annual International Conference

The Centre for Research, Maitreyi College, University of Delhi, organised a three-day Annual International Conference, Equinox 2022, under the aegis of Vantage: Journal of Thematic Analysis, from 11th to 13th August, 2022. Prof. Haritma Chopra, Officiating Principal, Maitreyi College was the coordinator of the conference and Dr. Gopi Devdutt Tripathy, Associate Professor, Department of Sociology, Dr. Brototi Roy, and Dr. Meena Yadav, Associate Professors, Department of Zoology, Maitreyi College, were the convenors. The theme of the conference was „The Expanding Frontiers of Knowledge‟.

Trop-2-Cells, Their Exosomal Cargo, and the Potential Impact on Diagnostics and Therapeutics in Breast Cancer: The Expanding Frontiers

Recently, an anti-trophoblast surface antigen-2 (Trop-2) antibody-drug conjugate targeting Trop-2 positive cancer cells has been approved for treating patients with unresectable locally advanced or metastatic triple-negative breast cancer, who have failed two or more lines of systemic chemotherapy. This has renewed the interest in translational research of Trop-2 positive breast cancer, the gene TACSTD2 and microRNAs that interact with it, and the signaling networks sparked by Trop-2 mediated signaling. In addition, this opinion paper argues that exosomes, extracellular vesicles that are released from Trop-2 positive cancer cells, could play a significant role in cancer progression. Furthermore, diagnostic applications using Trop-2-released exosomes, the cargo exosomes carry, which could be any genetic information such as specific miRNAs, adhesion molecules such as integrins, and metabolites, are yet to be explored in breast cancer patients. Most of the evidence and data are obtained from studies in epithelial cancers other than breast cancers, which have been introduced in the current paper. Therefore, this article briefly summarizes previously published data on other cancer types, forms some hypotheses, and proposes research questions and directions that may be explored further.

Father Knows Best: “Protecting” Women through State Surveillance and Social Control in Anti‐Abortion Policy

Drawing on a feminist surveillance and social control framework, we conduct a manifest and latent content analysis of anti‐abortion policies passed in the United States in either a state's House or Senate from 2010 to 2015 to systematically assess the scope, content, and implicit meaning of 282 anti‐abortion bills. We find that out of the 727 anti‐abortion measures contained in this legislation, 622 incorporate surveillance, and social control mechanisms that operate together to socially construct women as a dependent population in need of government protection on two fronts: protection for women and their “unborn,” and protection from abortion providers. Fusing together womanhood and motherhood, these policies essentialize motherhood, depicting women as an uninformed group in need of protection from their own ignorance and the practices of abortion providers who are constructed as an unethical group of health‐care practitioners.Related ArticlesHussey, Laura S. 2013. “Crisis Pregnancy Centers, Poverty, and the Expanding Frontiers of American Abortion Politics.”Politics & Policy41 (6): 985‐1011.https://doi.org/10.1111/polp.12054Medoff, Marshall H. 2010. “State Abortion Policy and the Long‐Term Impact of Parental Involvement Laws.”Politics & Policy38 (2): 193‐221.https://doi.org/10.1111/j.1747-1346.2010.00235.xWolff, Kristina B. 2011. “Panic in the ER: Maternal Drug Use, the Right to Bodily Integrity, Privacy, and Informed Consent.”Politics & Policy39 (5): 679‐714.https://doi.org/10.1111/j.1747-1346.2011.00313.x

Students’ Attitudes and Perspectives Towards Using Videos in Technology Assisted English Class

Expanding frontiers of technology in higher education enables the massive use of multimedia in traditional classrooms. In English classes, instructors tend to use videos as teaching materials to engage students’ attention and interest, trying to improve students’ learning outcomes eventually. Videos tools poises both opportunities and challenges to teaching and learning, however, its full function as an effective teaching approach has not been realized completely. Based on an survey on English learners in a comprehensive university, this current study focuses on students’ attitude and perspectives towards using videos in English classes, including their reasons for supporting or against using video in class; their focus of attention; their preference for the subject matters, durance and subtitles of the videos; their attitude towards activities based on videos, etc. It is hoped that with the findings of this study, instructors may have a better understanding on the needs of students, thus using videos in technology assisted English classes could be more effective and efficient.

Integrating Concept Maps into a Medical Student Oncology Curriculum.

Expanding frontiers of knowledge have prompted medical schools to reconsider how best to promote learning in the face of information overload. Concept mapping (CM) promotes knowledge retention and integration. Students have perceived CM positively in prior studies, but the feasibility and utility of integrating CM into a medical student oncology curriculum as a learning and assessment tool have not been described. At the University of California, San Francisco, 152 medical students in a second-year hematology/oncology course produced concept maps about a single cancer type over 4weeks. We collected student evaluations about CM. Two of three graders independently scored each map using a standard rubric. We compared CM scores with USMLE Step 1 scores and clerkship grades using regression. All students produced a concept map. Student perception was mixed, and students provided feedback to improve CM utility as a learning tool. Grading was feasible, and inter-rater reliability was high. CM scores did not predict USMLE Step 1 scores or clerkship grades. CM was feasible as a learning tool, and we present strategies based on student feedback and literature review to improve utility. CM was feasible and reliable as an assessment tool; additional validity evidence may improve utility. Future studies should explore whether CM integrated into medical student oncology curricula early, serially, and collaboratively, with iterative practice and feedback, may predict meaningful learning and performance outcomes.

Secretary of State for Justice v Windle: The Expanding Frontiers of Mutuality of Obligation?

<i>Secretary of State for Justice v Windle</i>: The Expanding Frontiers of Mutuality of Obligation?

Crisis Pregnancy Centers, Poverty, and the Expanding Frontiers ofAmerican Abortion Politics

Pro‐life “crisis pregnancy centers” are an increasingly important venue for theAmerican abortion conflict, yet scholars know little about them. The increasing concentration of abortion among the poor also potentially heightens their relevance since they aim to reduce abortion through offers of practical support. This article describes this branch of the pro‐life movement, focusing on its approach to poverty and the political factors that may shape it. My national, mixed‐method study of pro‐life pregnancy centers finds that they devote substantial attention to poverty, frequently collaborate with social welfare agencies, and claim that a compassionate, “woman‐centered” approach differentiates them from other pro‐life groups. Despite this, there is little evidence that the development of such centers is related to conflict in the pro‐life movement over poverty.Related ArticlesCarmines,Edward G.,Jessica C.Gerrity, andMichael W.Wagner.2010. “.”Politics &amp; Policy38():1135‐1158.http://onlinelibrary.wiley.com/doi/10.1111/j.1747‐1346.2010.00272.x/abstractGainous,Jason,Stephen C.Craig, andMichael D.Martinez.2008. “.”Politics &amp; Policy36():972‐1004.http://onlinelibrary.wiley.com/doi/10.1111/j.1747‐1346.2008.00147.x/abstractMedoff,Marshall H.2010. “.”Politics &amp; Policy38():193‐221.http://onlinelibrary.wiley.com/doi/10.1111/j.1747‐1346.2010.00235.x/abstractRelated MediaGibbs,Nancy.2007. “.” . February 15.http://www.time.com/time/magazine/article/0,9171,1590444,00.htmlFilm Clip.2012. “.” February 18.http://www.youtube.com/watch?v=lG412TvBTMo

E5. SenoNetwork▪: Expanding frontiers and reflecting patterns of breast cancer care around the world

E5. SenoNetwork▪: Expanding frontiers and reflecting patterns of breast cancer care around the world

Interpreting in multilingual, multicultural contexts

Seventh Volume in the Studies in Interpretation Series Nineteen international authorities contribute their research and findings to in Multilingual, Multicultural Contexts, probing the complex nature of interpreted interaction involving Deaf and hearing people of diverse linguistic and cultural backgrounds. They also analyze the contextualized interpreting practices and considerations that transpire from this diversity. In three parts, this trenchant collection shows how Deaf and hearing people use language in fluctuating ways to connect with each other. The chapters in Part 1 Expanding Frontiers: ASL-English-Spanish Interpreting in the United States consider sign language interpreting at the border between Baja California and the state; trilingual video relay service (VRS) interpreting; and constructing a valid, reliable trilingual interpreting testing instrument. Part 2 Mediating Indigenous Voices explores how to construct roles in a Maori Deaf trilingual context; considerations for interpreting signed languages of American Indian Communities; and interpreting for indigenous Deaf clients in far north Queensland, Australia. In the final section, Part 3 Globalizing: Interpreting in International Contexts protocols for interpreting in multilingual international conferences are analyzed. The last chapter describes the arduousness of sign language interpreting in multilingual, international settings. It acts as a fitting conclusion to this examination of the challenges to the sociolinguistic repertoire of interpreters mediating across multiplex combinations of culture and language.

Introduction

These papers were originally presented at the retirement conference for Prof. John F. Richards, which was held at Duke University on September 29–30, 2006. The conference, entitled ‘Expanding Frontiers in South Asian and World History’, brought together students, colleagues and associates of Prof. Richards to discuss themes that have marked Richards's work as a historian in an academic career of almost 40 years. These themes focused on ‘frontiers’ in multiple contexts, all relating to Richards's work: frontiers and state building; frontiers and environmental change; cultural frontiers; frontiers, trade and drugs; and frontiers and world history.

Commentary on "Expanding Frontiers".

Commentary on "Expanding Frontiers".

Commentary on "Expanding Frontiers'.

Commentary on "Expanding Frontiers'.

Commentary on "Expanding Frontiers".

Commentary on "Expanding Frontiers".

The Expanding Frontiers of Anaesthesiology: the 20th Meeting of the European Academy of Anaesthesiology

The Expanding Frontiers of Anaesthesiology: the 20th Meeting of the European Academy of Anaesthesiology

Blindness Research: the Expanding Frontiers. A Liberal Studies Perspective

Blindness Research: the Expanding Frontiers. A Liberal Studies Perspective

The President's Page: Expanding frontiers of geophysics

It has long been observed that scientific inquiry is greatly stimulated and benefited when previously separate disciplines begin to converge on a common problem, or when a discir pline finds entirely new fields of inquiry opening before it. In the former case the interplay of differing insights and the clash of different points of view generate an increased flow of ideas and results; in the latter the discipline experiences a beneficial freedom from past tradition that speeds up progress.

Problems of Blindness

Blindness Research The Expanding Frontiers. Edited by Maxwell H. Goldberg and John R. Swinton. (A Liberal Studies Perspective.) Pp. xvi + 544. (Pennsylvania State University Press: University Park, Pennsylvania, and London, September 1969.) $12.50; 119s.

An International Law of Science: Orders on Man's Expanding Frontiers

An International Law of Science: Orders on Man's Expanding Frontiers