ViewpointLast Word on Viewpoint: Lung mechanical constraints: the Achilles heel of excess exertional ventilation for prognosis assessment?Paulo de Tarso Müller, Gaspar Rogério Chiappa, Pierantonio Laveneziana, Ralf Ewert, and José Alberto NederPaulo de Tarso MüllerLaboratory of Respiratory Pathophysiology (LAFIR), Federal University of Mato Grosso do Sul (UFMS)/Maria Aparecida Pedrossian Hospital (HUMAP), Campo Grande, BrazilCorrespondence: P.T. Müller ([email protected]).Search for more papers by this author, Gaspar Rogério ChiappaHuman Movement and Rehabilitation Graduate Program, Evangelical University of Goiás, Anapolis, BrazilSearch for more papers by this author, Pierantonio LavenezianaSorbonne Université, INSERM, UMRS1158 Neurophysiologie Respiratoire Expérimentale et Clinique, Paris, FranceAP-HP, Groupe Hospitalier Universitaire APHP-Sorbonne Université, Hôpitaux Pitié-Salpêtrière, Saint-Antoine et Tenon, Service des Explorations Fonctionnelles de la Respiration, de l'Exercice et de la Dyspnée (Département R3S), Paris, FranceSearch for more papers by this author, Ralf EwertDepartment of Internal Medicine B, University Medicine Greifswald, Greifswald, GermanySearch for more papers by this author, and José Alberto NederLaboratory of Clinical Exercise Physiology and Respiratory Investigation Unit, Queen’s University & Kingston General Hospital, Kingston, Ontario, CanadaSearch for more papers by this authorPublished Online:06 Feb 2023https://doi.org/10.1152/japplphysiol.00773.2022MoreSectionsFull TextPDF (235 KB)Download PDF ToolsExport citationAdd to favoritesGet permissionsTrack citations ShareShare onFacebookTwitterLinkedInWeChat "Last Word on Viewpoint: Lung mechanical constraints: the Achilles heel of excess exertional ventilation for prognosis assessment?." Journal of Applied Physiology, 134(2), pp. 385–386REFERENCES1. Müller PT, Chiappa GR, Laveneziana P, Ewert R, Neder JA. Lung mechanical constraints: the Achilles heel of excess exertional ventilation for prognosis assessment? J Appl Physiol (1985). doi:10.1152/japplphysiol.00059.2022. Link | Google Scholar2. Agostoni P, Menon A, Shyam V, Calverley PM. Commentaries on Viewpoint: Lung mechanical constraints: the Achilles heel of excess exertional ventilation for prognosis assessment? J Appl Physiol (1985). doi:10.1152/japplphysiol.00753.2022.Link | Google Scholar3. Apostolo A, Laveneziana P, Palange P, Agalbato C, Molle R, Popovic D, Bussotti M, Internullo M, Sciomer S, Bonini M, Alencar MC, Godinas L, Arbex FF, Garcia G, Neder JA, Agostoni P. Impact of chronic obstructive pulmonary disease on exercise ventilatory efficiency in heart failure. Int J Cardiol 189: 134‐–140, 2015. doi:10.1016/j.ijcard.2015.03.422.Crossref | PubMed | ISI | Google Scholar4. Rocha A, Arbex FF, Sperandio PA, Souza A, Biazzim L, Mancuso F, Berton DC, Hochhegger B, Alencar MCN, Nery LE, ÓDonnell DE, Neder JA. Excess ventilation in chronic obstructive pulmonary disease–heart failure overlap. Implications for dyspnea and exercise intolerance. Am J Respir Crit Care Med 196: 1264–1274, 2017. doi:10.1164/rccm.201704-0675OC.Crossref | PubMed | ISI | Google Scholar5. Neder JA, Rocha A, Alencar MCN, Arbex F, Berton DC, Oliveira MF, Sperandio PA, Nery LE, O'Donnell DE. Current challenges in managing comorbid heart failure and COPD. Expert Rev Cardiovasc Ther 16: 653–673, 2018. doi:10.1080/14779072.2018.1510319.Crossref | PubMed | ISI | Google Scholar6. Neder JA, Phillips DB, O'Donnell DE, Dempsey JA. Excess ventilation and exertional dyspnoea in heart failure and pulmonary hypertension. Eur Respir J 60: 2200144, 2022. doi:10.1183/13993003.00144-2022. Crossref | PubMed | Google Scholar Previous Back to Top Next Download PDF FiguresReferencesRelatedInformation Related ArticlesCommentaries on Viewpoint: Lung mechanical constraints: the Achilles heel of excess exertional ventilation for prognosis assessment? 06 Feb 2023Journal of Applied Physiology More from this issue > Volume 134Issue 2February 2023Pages 385-386 Crossmark Copyright & PermissionsCopyright © 2023 the American Physiological Society.https://doi.org/10.1152/japplphysiol.00773.2022PubMed36745710History Received 21 December 2022 Accepted 23 December 2022 Published online 6 February 2023 Published in print 1 February 2023 Metrics