In <italic xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">multiple-instance learning</i> (MIL), each training example is represented by a bag of instances. A training bag is either negative if it contains no positive instances or positive if it has at least one positive instance. Previous MIL methods generally assume that training bags are fully labeled. However, the exact labels of training examples may not be accessible, due to security, confidentiality, and privacy concerns. Fortunately, it could be easier for us to access the pairwise similarity between two bags (indicating whether two bags share the same label or not) and unlabeled bags, as we do not need to know the underlying label of each bag. In this paper, we provide the first attempt to investigate MIL from only similar-dissimilar-unlabeled bags. To solve this new MIL problem, we first propose a strong baseline method that trains an instance-level classifier by employing an unlabeled-unlabeled learning strategy. Then, we also propose to train a bag-level classifier based on a convex formulation and theoretically derive a generalization error bound for this method. Comprehensive experimental results show that our instance-level classifier works well, while our bag-level classifier even has better performance.