Evaluation Of Research Evidence Research Articles

The origin and possible mechanism of embryonic cell-free DNA release in spent embryo culture media: a review.

The presence of cell-free DNA in spent embryo culture media (SECM) has unveiled its possible utilization for embryonic ploidy determination, opening new frontiers for the development of a non-invasive pre-implantation genetic screening technique. While a growing number of studies have shown a high concordance between genetic screening using cell-free DNA (cfDNA) and trophectoderm (TE), the mechanism pertaining to the release of cfDNA in SECM is largely unknown. This review aims to evaluate research evidence on the origin and possible mechanisms for the liberations of embryonic DNA in SECM, including findings on the self-correction abilities of embryos which might contribute to the presence of cfDNA. Several databases including EMBASE, PUBMED, and SCOPUS were used to retrieve original articles, reviews, and opinion papers. The keywords used for the search were related to the origins and release mechanism of cfDNA. cfDNA in SECM originates from embryonic cells and, at some levels, non-embryonic cells such as maternal DNA and exogenous foreign DNA. The apoptotic pathway has been demonstrated to eliminate aneuploid cells in developing mosaic embryos which might culminate to the release of cfDNA in SECM. Nonetheless, there is a recognized need for exploring other pathways such as cross-talk molecules called extracellular vesicles (EVs) made of small, round bi-layer membranes. During in vitro development, embryos physiologically and actively expel EVs containing not only protein and microRNA but also embryonic DNA, hence, potentially releasing cfDNA of embryonic origin into SECM through EVs.

Research translation to improve carer smoking cessation support in a paediatric ward of a regional hospital in the Northern Territory.

Health professionals have described barriers to providing carer smoking cessation support in children's wards. This article reports the findings of a research translation process that explored opportunities and developed pathways for change. A facilitated discussion workshop and scheduled stakeholder meetings were used to evaluate research evidence and translate it to an evidence-informed organisational change process, with actions for implementation. Workshop and meeting participants were senior health staff with either a pharmacist, personnel with expertise in alcohol and other drugs, medical or nursing backgrounds, and who held senior managerial roles who worked in a hospital in the Northern Territory. A qualitative approach was used. The data from the workshop were transcribed and analysed using thematic analysis. The first author took notes for meetings that were not recorded and analysed these alongside the transcripts. The process was able to initiate change to overcome barriers to providing carer smoking cessation support. All participants agreed to prioritise and make carer smoking cessation everybody's responsibility and supported a systematic approach, including provision of nicotine replacement therapy, new record-keeping systems, and training to address staff knowledge deficits and skills gaps. This movement to solution-focused change continued after the workshop. With some preparation, a research translation workshop and meetings with selected leaders can initiate organisational change in similar settings and is consistent with theories of planned change. SO WHAT?: This article describes the use of a process to support health promotion through new policies and practices following research which identified barriers in a hospital ward.

Technological trends & software engineering education: a systematic review study

The quality of software engineering education is influenced by the consideration of modern industrial trends, IT trends and software development methodologies. The transition to a new level of industry - “Industry 4.0”, characterized by robotics and cyber-socialization, brings a wave of new, never-before-seen challenges to the field of IT and programming. Under such conditions, it is impos- sible to achieve the desired synergistic effect without the formation of an appropriate informational and educational environment in institutions of higher education. One of the sources of the content of such an environment can be the publications of the world scientific community registered in international scientometric databases. On this basis, it becomes possible not only to provide effective digital educational content, but also to choose and use the latest technological means of learning support. A targeted review of primary sources in the Web of Science Core Collection database made it possible to identify, select, synthesize and evaluate research evidence relevant to the research questions: (i) what technological trends are analyzed in research, (ii) what information technolo- gies are considered in research, (iii) what strategies are reflected in publications to overcome the above challenges of SE teaching and learning. According to the results of the study, we offer to improve the educational and methodological support of software engineering education based on ontological modeling of the integration of the requirements of modern trends in the development of the industry and the IT sector, international recommendations and the capabilities of technological teaching aids. This approach is a good basis for the processes of intellectualization of information systems of the educational environment and the construction of appropriate technological educational tools on their basis.

Self-assessed Competence of Nurses in Critical Care Units in Malawi: A Cross-sectional Survey

Background: The birth of a premature infant and admission to the NICU is often unexpected and traumatic for families, leading to increased distress and can negatively impact parental-infant attachment. Appropriate interventions can help to lessen the negative impact of a NICU admission on families, improving parental mental health, reducing distress, enhancing parent- infant relationships, and improving the long-term physical, cognitive, emotional, and social development of the infant.
 Aims: The purpose of this study is to examine and evaluate research evidence on the effectiveness of current interventions for improving parental distress in the NICU. Methods: A rapid review was conducted utilizing a protocol based on the Virginia Commonwealth University guidance. Keyword searches were conducted on CINAHL, MEDLINE, and PsychINFO, and studies were selected according to pre-defined eligibility criteria, published between January 2015 and January 2020. The literature search included primary studies of interventions with parental stress and/or anxiety reduction as outcomes.
 Results: A total of 14 articles were included, evaluating the effectiveness of 13 different interventions, including narrative writing, art therapy, structured nursing interventions, anxiety counselling, spiritual care, organizational change, music therapy, relaxation, and mindfulness techniques. With the Pexception of three, all the studies found significant results in the reduction of stress and/or anxiety levels of the subjects, with mothers having overall higher levels of stress indicated by higher stress scores on standardized measurement tools.
 Conclusion: There is a need for ongoing assessment of parental distress and integration of appropriate interventions within the NICU settings. In this review, both individualized and group interventions including narrative writing, art therapy, music therapy, spiritual care, activity-based group therapy, music therapy, audio-assisted relaxation techniques, mindfulness based neurodevelopmental care, cognitive behavioral based counselling, family nurture intervention and a structured nursing intervention were shown to be effective in reducing parental stress and/or anxiety in the NICU. The small scale of the studies included in this review impact generalizability to a broader audience and emphasizes the need for larger scope, multi-center studies at an international level to build on and broaden our level of knowledge on how to better support families and reduce parental distress in the NICU.

Effectiveness of Current Interventions to Alleviate Parental Distress in the NICU: A Rapid Review

Background: The birth of a premature infant and admission to the NICU is often unexpected and traumatic for families, leading to increased distress and can negatively impact parental-infant attachment. Appropriate interventions can help to lessen the negative impact of a NICU admission on families, improving parental mental health, reducing distress, enhancing parent- infant relationships, and improving the long-term physical, cognitive, emotional, and social development of the infant.
 Aims: The purpose of this study is to examine and evaluate research evidence on the effectiveness of current interventions for improving parental distress in the NICU.
 Methods: A rapid review was conducted utilizing a protocol based on the Virginia Commonwealth University guidance. Keyword searches were conducted on CINAHL, MEDLINE, and PsychINFO, and studies were selected according to pre-defined eligibility criteria, published between January 2015 and January 2020. The literature search included primary studies of interventions with parental stress and/or anxiety reduction as outcomes.
 Results: A total of 14 articles were included, evaluating the effectiveness of 13 different interventions, including narrative writing, art therapy, structured nursing interventions, anxiety counselling, spiritual care, organizational change, music therapy, relaxation, and mindfulness techniques. With the Pexception of three, all the studies found significant results in the reduction of stress and/or anxiety levels of the subjects, with mothers having overall higher levels of stress indicated by higher stress scores on standardized measurement tools.
 Conclusion: There is a need for ongoing assessment of parental distress and integration of appropriate interventions within the NICU settings. In this review, both individualized and group interventions including narrative writing, art therapy, music therapy, spiritual care, activity-based group therapy, music therapy, audio-assisted relaxation techniques, mindfulness based neurodevelopmental care, cognitive behavioral based counselling, family nurture intervention and a structured nursing intervention were shown to be effective in reducing parental stress and/or anxiety in the NICU. The small scale of the studies included in this review impact generalizability to a broader audience and emphasizes the need for larger scope, multi-center studies at an international level to build on and broaden our level of knowledge on how to better support families and reduce parental distress in the NICU.

Advancing in the institutionalization of Evidence-Informed Policy in Brazil

Abstract EVIPNet Brazil was launched in 2007, coordinated by the Ministry of Health. Its expansion has promoted the institutionalization of a national knowledge translation platform, and has also been active at the local level. Local Health Evidence Labs were implemented to institucionalize working groups linked to EVIPNet. In this multiple case study, we discuss the advances in the institutionalization of Evidence-Informed Policy-making in Brazil, based on a mapping of the Health Evidence Labs' institutional capacity to acquire, evaluate, adapt and apply evidence and analyzed organizational arrangements and implementation barriers. The coordinators of 15 responded to a self-assessment questionnaire from the Canadian Health Services Research Foundation. The main products reported are evidence briefs and deliberative dialogues focused on regional problems, training activities and different kinds of rapid responses. Health Evidence Labs have the resources to acquire and evaluate research evidence, but have a low capacity to adapt and apply evidence, indicating that they do not have all the factors (skills, structures, processes, and organizational culture) to promote and use research results in decision-making. The lower capacity to 'adapt' and 'apply' evidence may be related to low development of exchange process with external experts. Governance is joined between managers of the departments with technical bodies; the service provision occurs to attend internal and external demands; financing is public or utilizing public research calls. The implementation barriers described are the staff turnover, inadequate funding arragements for develop knowledge translation products, paid access to evidence databases, lack of a repository for their production, and lack of monitoring and evaluation. Brazil has improved in the institutionalization of evidence-informed policy but still some important barriers to achieve a complete national knowledge translation platform. Key messages Brazil has institutionalized evidence-informed policy from the structuring of EVIPNet Brazil Network. To achieve the network sustainability, it is vital to consider the alignment of organizational elements with an emphasis on governance, financing, and its monitoring.

Evidence-based Medicine (Dr. Gordon Guyatt)


 
 
 
 Dr. Gordon Guyatt is a Distinguished Professor in the Department of Health Research Methods, Evidence, and Impact at McMaster University, and is one of the founders of “evidence-based medicine.” He has played a significant role in over 30 major clinical studies, including large-scale observational and randomized trials and has extensive expertise in study methodology. As the co-founder and co-chair of the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) working group, he has been intimately involved in the development and evolution of the GRADE approach for evaluating research evidence.
 
 
 

Assessing the impact of health and clinical research in British Columbia health authorities.

This article describes results of a healthcare research impact survey conducted in two health authorities in British Columbia. A tailored research impact framework formed the basis for the survey created and used to collect quantitative and qualitative data from a sample of employees and academic faculty who had completed research in both health authorities. In all, 178 responses were collected for a combined response rate of 34%. Although there are differences between the two health authorities, the data confirm that the majority of respondents were successful in disseminating their research; 30% of both Island and Fraser Health studies reported improved safety, whether through avoidance of adverse drug effects, or reduced nosocomial infections, and as high as 26% of studies reported a reduction in morbidity or mortality. We conclude with recommendations that build on existing research capacity infrastructure to enhance the generation, implementation, and evaluation of research evidence within healthcare organizations.

The impact of a small-group educational intervention for allied health professionals to enhance evidence-based practice: mixed methods evaluation

BackgroundHealthcare professionals are recommended to use evidence-based practice (EBP) principles to update and improve clinical practice. Well-designed educational initiatives, together with practice and feedback opportunities can improve individuals’ EBP knowledge, skills and attitudes.MethodsA concurrent mixed methods assessment was designed to evaluate the effectiveness and feasibility of four monthly workshops on allied health professionals’ knowledge, skills, self-efficacy and behaviour. In between workshops, professionals were encouraged to practice and integrate EBP learnings with colleagues in their workplace.Participants completed three pre and post intervention assessments: Evidence-based Practice Confidence Scale; adapted Fresno test; and an adapted EBP Implementation Scale. A purpose designed satisfaction questionnaire was completed immediately after the educational intervention and follow up focus groups were conducted after 3 months.Mean change in assessment data was quantitatively assessed and comments from the clinician satisfaction questionnaire and focus groups were thematically analysed and interpreted together with quantitative data using the Classification Rubric for EBP Assessment tools in Education (CREATE).ResultsSixteen allied health professionals participated in the EBP workshops and completed all baseline and post intervention assessments. Seven clinicians participated in follow up focus groups. All clinicians reported a positive reaction to the learning experience, preferring short monthly workshops to a full day session. They self-reported improvements in self-efficacy (mean change 15 p < 0.001) and implementing EBP behaviours (mean change 7, p < 0.001) from pre- to post-intervention. Although the positive change in EBP knowledge measured by the adapted Fresno test was not statistically significant (mean change 10, p = 0.21), clinicians described examples of improved knowledge and skills across all five key steps of EBP during the focus groups. A further, post hoc analysis of individual questions in the two self-reported scales indicated consistent improvement across key EBP knowledge and skills.ConclusionsA tailored small group EBP education intervention can enhance AHPs’ self-efficacy to develop answerable questions, search the literature, critically appraise, apply and evaluate research evidence. Through practicing these behaviours and sharing new learning with their peers, allied health professionals can enhance their capability and motivation to use research evidence to potentially improve clinical practice.

When the “Best Available Evidence” Doesn’t Win: How Doubts About Science and Scientists Threaten the Future of Evidence-Based Management

The well documented academic-practice gap has frequently been viewed as a problem to be solved via evidence-based management. Evidence-based management focuses heavily on aggregating and evaluating research evidence to address practical questions via meta-analysis and other forms of systematic review, as well as educating managers and management students on how to differentiate strong from weak research methods. The assumption has been that if researchers produce stronger research findings and disseminate them in manager- and student-accessible venues, the results will be believed and implemented if appropriate to the context. However, these strategies alone are woefully insufficient, as a growing body of evidence suggests that even when individuals are aware of research findings supported by a vast majority of studies, they often choose not to believe them. Sources of this disbelief include growing public distrust of academics, scientific research, and professional expertise in general, as well as negative emotional reactions to specific research findings that threaten people’s cherished beliefs, self-image, self-interest, or social identity. This editorial takes an interdisciplinary approach to explain why people might not believe management research findings and offers strategies for increasing public trust of academics and reducing resistance to self-threatening research findings.

The most important risk factors affecting mental health during pregnancy: a systematic review.

Pregnant women comprise a vulnerable population owing to the changes they experience in various stages that affect their mental health. Mental health problems affects nearly one-fifth of pregnant women during the prenatal and postpartum periods. Millennium Development Goals 4 and 5 focus on maternal and child health and specify that overall health cannot be reached without mental health. The aim of this comprehensive systematic review was to evaluate research evidence on the determinants of antenatal mental health disorders among Iranian women. Using a systematic literature review of observational studies in English and Farsi we focused on Iranian women being evaluated for the determinants of antenatal mental health problems. PubMed, Scopus, ISI Web of Science, Scientific Information Databases (SID), Global Medical Article Limberly, Iranian Biomedical Journal and the Iranian Journal Database were independently searched to identify articles published during 2000-2016. Thirty-one studies met the inclusion criteria and the results showed a significant relationship between antenatal mental health risks and variables such as lack of social support, marital status, domestic violence, unintended pregnancy and socioeconomic status. The paucity of high quality research evidence limited proper evidenced-based planning and generating results deemed essential to address antenatal mental health issues for Iranian pregnant women. Our results showed that socioeconomic status and marital quality are the most important risk factors for disturbing mental health among Iranian pregnant women.

Promoting a healthy cities agenda through indicators: development of a global urban environment and health index

ABSTRACTThere is a growing awareness among city leaders and policy-makers of the impact of the urban environment on health outcomes and inequalities. Increasingly, practitioners in built environment city departments, such as housing, planning, transport and regeneration, seek new tools and guidance to understand how their respective policies and decisions can support the creation of healthier cities. This paper presents the development of a global index to help city leaders and practitioners understand their role in delivering health outcomes through urban environment policies and programmes. The Building Research Establishment’s international Healthy Cities Index (BRE HCI) contains 10 environment categories and 58 indicators, supported by a causal pathways framework. This was achieved through an iterative process including: stakeholder engagement, evaluating research evidence, selecting indicators and identifying data sources. We tested the index and causal pathways approach on two case study cities: Dubai and London. We found that they contributed to: raising awareness of the links between the environment and health; identifying shared responsibilities and the need to work across departmental silos; and uncovering the competing demands faced by some departments (and private sector stakeholders) as they seek to deliver health promoting environments alongside other objectives.

Role of evidence-based medicine in the cultivation of clinical medicine undergraduates' scientific research ability

The paper described the concept of evidence-based medicine and its guiding role in clinical practice and scientific research. It emphasized the importance of teaching evidence-based medicine in clinical medicine teaching of medical college students, and put forward some suggestions on how to carry out evidence-based medicine teaching among undergraduate students. In the course of undergraduate study, students should have preliminary grasp of how to apply the theory of clinical epidemiology to evaluate the evidence of clinical research so that they could evaluate the authenticity, importance and applicability of the research evidence. Besides, they could correctly understand and apply the evidence of evidence-based medicine in clinical practice in the future, and at the same time cultivate their scientific research thinking and innovative ability. Key words: Evidence-based medicine; Postgraduates; Clinical medicine teaching; The evaluation of research evidence

Systematic review protocol of interventions to improve the psychological well-being of general practitioners.

BackgroundThe challenges and complexities faced by general practitioners are increasing, and there are concerns about their well-being. Consequently, attention has been directed towards developing and evaluating interventions and strategies to improve general practitioner well-being and their capacity to cope with workplace challenges.Methods/designThis systematic review aims to evaluate research evidence regarding the effectiveness of interventions designed to improve general practitioner well-being. Eligible studies will include programmes developed to improve psychological well-being that have assessed outcomes using validated tools pertaining to well-being and related outcomes. Only programmes that have been evaluated using controlled study designs will be reviewed. An appropriately developed search strategy will be applied to six electronic databases: the Cochrane Database of Systematic Reviews, MEDLINE, Embase, CINAHL, PsycINFO and Web of Science. Studies will be screened in two stages by two independent reviewers. A third reviewer will arbitrate when required. Pre-specified inclusion and exclusion criteria will be assessed during a pilot phase early on in the review process. The Cochrane data extraction form will be adapted and applied to each eligible study by two independent reviewers, and each study will be appraised critically using standardised checklists from the Cochrane Handbook. Methodological quality will be taken into account in the analysis of the data and the synthesis of results. A narrative synthesis will be undertaken if data is unsuited to a meta-analysis.DiscussionThe systematic review will be reported according to the Preferred Reporting Items for Systematic Reviews and Meta-analyses guidance. This will be the first systematic review on this topic, and the evidence synthesis will aid decision-making by general practitioners, policy makers and planners regarding ways in which to improve GP well-being. Findings will be disseminated at general practitioner meetings, conferences and in professional and peer-reviewed journals.Systematic review registrationPROSPERO CRD42015017899Electronic supplementary materialThe online version of this article (doi:10.1186/s13643-015-0098-z) contains supplementary material, which is available to authorized users.

Shared decision making for psychiatric medication management: beyond the micro-social.

BackgroundMental health care has lagged behind other health‐care domains in developing and applying shared decision making (SDM) for treatment decisions. This is despite compatibilities with ideals of modern mental health care such as self‐management and recovery‐oriented practice, and growing policy‐level interest. Psychiatric medication is a mainstay of mental health treatment, but there are known problems with prescribing practices, and service users report feeling uninvolved in medication decisions and concerned about adverse effects. SDM has potential to produce better tailoring of psychiatric medication to individuals' needs.ObjectivesThis conceptual review argues that several aspects of mental health care that differ from other health‐care contexts (e.g. forms of coercion, questions about service users' insight and disempowerment) may impact on processes and possibilities for SDM. It is therefore problematic to uncritically import models of SDM developed in other health‐care contexts. We argue that decision making for psychiatric medication is better understood in a broader way that moves beyond the micro‐social focus of a medical consultation. Contextualizing specific medication‐related consultations within longer term relationships, and broader service systems enables recognition of the multiple processes, actors and agendas that shape how psychiatric medication is prescribed, managed and used, and which may facilitate or impede SDM.ConclusionA broad conceptualization of decision making for psychiatric medication that moves beyond the micro‐social can account for why SDM in this domain remains a rarity. It has both conceptual and practical utility for evaluating research evidence, identifying future research priorities and highlighting fruitful ways of developing and implementing SDM in mental health care.

Evaluating evidence: defining levels and quality using critical appraisal mixed methods tools.

Evaluating evidence for the built environment is not easy, and many professionals struggle with the challenge of identifying the best available research. This article outlines the current state of science for evaluating evidence in healthcare design, drawing on previous discussion articles in this journal and introducing a Mixed Methods Appraisal Tool (MMAT), which can be used by professional designers to evaluate research evidence for healthcare design. Two case studies are provided to illustrate the use of the MMAT with an evidence levels algorithm.

Enhancing Client-centeredness in Parkinson's Disease Care: Attending to the Psychosocial Implications of Lived Experience

Evidence-based practice requires that clinicians interpret the best research evidence in the context of their clinical experience, while at the same time considering client knowledge and experiences. Although clinicians are becoming increasingly skilled at the evaluation of research evidence, the evidence-based practice process often neglects client values and self-identified health issues. Ignoring these key aspects of client-centered practice may lead to interventions that fail to target the implications of a client’s disease that are important to occupational participation and quality of life (QOL). A focus on client-centeredness is particularly important in progressive neurodegenerative disorders, such as Parkinson’s disease, where there are no known curative treatments, and interventions must instead focus on symptom management. In this paper, we explore the published literature on the psychosocial aspects of the lived experience among individuals with Parkinson’s disease, arguing that such literature provides insight into the implications of the disease and into potential treatment priorities. As such, this literature provides an additional form of evidence that raises awareness of the lived implications of this disease for clients’ occupations and QOL that, in turn, may lead clinicians to be more cognizant of client values and self-identified issues.

Developing and Using Evidence to Improve Rehabilitation Practice

Seel RT, Dijkers MP, Johnston MV. Developing and using evidence to improve rehabilitation practice.The Clinical Practice Committee of the American Congress of Rehabilitation sponsored this supplement to address 2 critical, related issues for the rehabilitation field: how to develop clinical rehabilitation research to generate useful, high-quality evidence and how to use evidence to improve rehabilitation practice. The 2 are linked by the methods of evidence-based practice (EBP) used to evaluate research evidence and make recommendations for practice. Supplement authors tackle challenges, such as identifying treatment effects and how study design decisions can impact the internal and external validity of research findings, in 4 articles that describe: a 3-phase process for the development of rehabilitation treatments; small-N study designs; the design, implementation, and statistical analysis of rehabilitation clinical trials; and observational research designs used to compare the effectiveness of rehabilitation treatments. Two articles present contemporary best methods for developing and evaluating rehabilitation prediction models and outcome measures. The supplement also addresses issues of evaluating research evidence and translating evidence into clinical decisions or recommendations. An overview of tools that EBP adherents have developed to help the clinician find, synthesize, and apply evidence is presented, followed by an article that identifies 8 primary steps in the production of a systematic review. The last article outlines 13 recommendations for improving systematic evidence reviews and applying their resulting knowledge to clinical practice. In addition to recommending best methods, the supplement addresses challenges specific to the behavioral complexity of developing rehabilitation research and applying it in a way that improves the health, function, and quality of life of persons served.

Has Occupational Science Taken Away the Occupational Therapy Evidence Base? A Debate

Health policy requires occupational therapy to demonstrate evidence-based clinical outcomes and efficiency in order to survive. This has significant implications for occupational therapy researchers and managers and suggests a re-evaluation of the profession's priorities for research. This opinion piece aims to stimulate debate regarding the impact of occupational science on occupational therapy and the need for research that evaluates the effectiveness of occupational therapy interventions. This is achieved by reflecting on a personal experience of evaluating research evidence for clinical guidelines and by exploring current and future challenges.

Translating Current Dietary Guidelines Into a Culturally Tailored Nutrition Education Program for Korean American Immigrants With Type 2 Diabetes

The purpose of this article is to describe the process of translating evidence-based dietary guidelines into a tailored nutrition education program for Korean American immigrants (KAI) with type 2 diabetes mellitus (DM). Community-based participatory research (CBPR) is a research process involving researchers and communities to build a collaborative partnership. The study was conducted at a community-based organization. In a total of 79 KAI (intervention, n = 40; control, n = 39) with uncontrolled type 2 DM (A1C ≥ 7.5%), 44.3% were female and the mean age was 56. 5 ± 7.9 years. A culturally tailored nutrition education was developed by identifying community needs and evaluating research evidence. The efficacy and acceptability of the program was assessed. In translating dietary guidelines into a culturally relevant nutrition education, culturally tailored dietary recommendations and education instruments were used. While dietary guidelines from the American Diabetes Association (ADA) were used to frame nutrition recommendations, additional content was adopted from the Korean Diabetes Association (KDA) guidelines. Culturally relevant intervention materials, such as Korean food models and an individually tailored serving table, were utilized to solidify nutritional concepts as well as to facilitate meal planning. Evaluation of the education revealed significantly increased DM-specific nutrition knowledge in the intervention group. The participants' satisfaction with the education was 9.7 on a 0 to 10-point scale. The systematic translation approach was useful for producing a culturally tailored nutrition education program for KAI. The program was effective in improving the participants' DM-specific nutrition knowledge and yielded a high level of satisfaction. Future research is warranted to determine the effect of a culturally tailored nutrition education on other clinical outcomes.