EU Ban Research Articles

Recovered water from fuel cells as a supply for Maisotsenko evaporative cooling systems in a hydrogen-powered urban bus

The EU ban on the sale of new petrol and diesel cars from 2035 requires finding sustainable alternatives both from an energy and an environmental point of view. The path now seems to be drawn towards a total electrification of public and private transportation sectors. However, the issue of the limited range of electric vehicles, particularly for heavy-duty ones, still needs to be addressed. The development of fuel cell vehicles powered by compressed hydrogen, not relying exclusively on batteries, can achieve ranges comparable to those powered by fossil-fuel. The development of hydrogen vehicles must proceed in parallel with increasing the efficiency of passenger compartment air conditioning, which requires a significant share of the total energy consumed. An efficient alternative to common vapor compression cooling systems is represented by evaporative coolers, in which water evaporation is used to cool an air flow. This study investigates the feasibility of utilizing the recovered water from the exhaust gas of a hydrogen PEM fuel cell, powering an urban bus, within a commercial indirect evaporative cooling system employing the Maisotsenko cycle. The cooling capacity of the proposed system was calculated to verify the possibility of implementing it on an urban bus. The water available at the cathode of the fuel cell and the water required by the evaporative cooler were evaluated under various conditions and compared. The calculations demonstrate that even under intense weather conditions, where approximately 40 kg of water may be required every hour, at least 10 % of water needed by the evaporative cooling system can be provided by the water produced through the hydrogen reaction. In mild weather conditions or by cooling the exhaust, it is possible to significantly increase the share of pure water supplied to the evaporative system. The integration of hydrogen fuel cells and evaporative coolers in bus equipment can be an energy-efficient, win–win solution. This configuration enables the dual utilization of the hydrogen employed to drive the fuel cell.

Actuarial implications and modeling of virus yellows on sugar beet after the EU's ban on neonics and climate change

Following the EU's decision to ban neonics, this article investigates the impacts of virus yellows on sugar beet yields under the ban and under current and future climates. Using a model that factors in key variables such as sowing dates, phenological stages, first aphid flight and aphid abundance, simulations are performed using long-period climate datasets as inputs. Coupled with incidence and sugar yield loss assumptions, this model allows to reconstruct the impact of virus yellows on sugar beet yields using a so called ‘as if’ approach. By simulating the effects of viruses over a long period-of-time, as if neonics weren't used in the past, this methodology allows an accurate assessment of risks associated with virus yellows, as well as impact of future agro-ecological measures.The analysis provides in addition an actuarial rating for an insurance policy that compensates the losses triggered by those viruses.

Developing an Ethical Evaluation Framework for Coercive Antimicrobial Stewardship Policies.

Antimicrobial resistance (AMR) has been declared one of the top ten global public health threats facing humanity. To address AMR, coercive antimicrobial stewardship policies are being enacted in some settings. These policies, like all in public health, require ethical justification. Here, I introduce a framework for ethically evaluating coercive antimicrobial stewardship policies on the basis of ethical justifications (and their limitations). I consider arguments from effectiveness; duty of easy rescue; tragedy of the commons; responsibility-tracking; the harm principle; paternalism; justice and development; a precautionary approach; and professional duties. I consider how these justifications might form the basis for developing a comprehensive ethical framework, and the need for this to be context-specific and aligned with the priorities, evidence and needs of the particular jurisdictions in which a policy is to be enacted. I demonstrate how the ethical justifications might be used by reference to an example policy of the EU ban on the use of certain human-critical antibiotics for livestock, before concluding with challenges for further development of the framework.

Online coupling of miniaturized HPLC and high performance thin layer chromatography by a fractionation unit for effect directed analysis

The rising discharge of anthropogenic chemicals into aquatic environments poses a significant threat, necessitating effective monitoring strategies. This study introduces an innovative approach to effect-directed analysis (EDA) by coupling liquid chromatography (LC) with high-performance thin-layer chromatography (HPTLC), utilizing a modified MALDI spotter. The objective is to optimize fractionation parameters for sample application and assess the method's viability in identifying acetylcholinesterase (AChE) inhibitors, specifically malathion, parathion, and chlorfenvinphos.The optimization process involves controlling sample volume, spot shape, and spot distances on HPTLC plates. Successful application is demonstrated by a miniaturized LC system coupled to the HPTLC plate via spotter, allowing effective separation and identification of AChE inhibitors. The study further explores the method's application to water samples from a river with predominantly agricultural drainage area.Spiked samples reveal distinct active spots, identified through extraction and subsequent high-resolution mass spectrometry (HRMS) measurements. However, results indicate the absence of AChE inhibitors in non-spiked water samples, affirming the efficacy of the EU ban on most organophosphate pesticides. The usefulness of HPTLC in separation of coeluting substances from HPLC is emphasized, demonstrating its suitability for the effect-directed analysis of complex samples.This work shows the integration of HPTLC with liquid chromatography for EDA, offering a powerful tool for identifying and monitoring AChE inhibitors in water samples. The approach addresses limitations in current monitoring strategies and provides insights into the presence and impact of chemicals in aquatic ecosystems. The study contributes to ongoing efforts to enhance water quality monitoring, aligning with the principles of the EU Water Framework Directive.

Effects of Dietary Supplementation of Lactobacillus farciminis and Lactobacillus rhamnosus on Growth and Production Indicators of Broiler Chickens

In response to the 2006 EU ban on the use of antibiotics as growth promoters, researchers have sought alternatives, leading to a focus on the beneficial effects of probiotics on chickens. The aim of this study was to evaluate the effect of the probiotic mixture containing Lactobacillus (L.) farciminis CNCM-I-3699 and Lactobacillus rhamnosus CNCM-I-3698 on the growth, production indicators, and edible organs of broiler chickens. Three trials were conducted, each consisting of 260 newly hatched Ross 308 broiler chicks (males and females) from a commercial hatchery, randomly allocated into control (n = 130) and probiotic-supplemented groups (n = 130). The dietary treatments were basal diet for the control group and basal diet + the mixture of L. farciminis CNCM-I-3699 (2.1010 GU/g) and L. rhamnosus CNCM-I-3698 (2.1010 GU/g) at a rate of 4g/10kg of diet for the probiotic supplemented group. Broilers were raised until day 35 of age, and their body weight and feed intake were recorded on days 1, 7, 14, 21, 28, and 35. All broiler chickens were weighed on the first day. The investigated parameters included average weight gain, feed conversion ratio, cumulative feed intake, and the European Broiler Index. Daily mortality was recorded. The average organ’s relative weight was calculated for each group on days 1, 7, 14, 21, 28, and 35. Although both groups yielded positive results regarding growth and production indicators, no significant differences were observed between the two groups, suggesting that probiotics may not provide expected outcomes when appropriate conditions and age-related requirements are met. The probiotic-supplemented group exhibited significantly accelerated growth in the heart and liver. However, relative organ weights did not differ significantly between the groups.

Efficient Renewable Electricity Support: Designing an Incentive-compatible Support Scheme

Most existing renewables support schemes distort location and dispatch decisions. Many impose unnecessary risk on developers, increasing support costs. Efficient policy sets the right carbon price, supports capacity not output, ensures efficient dispatch and location. The EU bans priority dispatch and requires market-based bidding, but does not address the underlying problem that payment is conditional on generation, amplifying incentives to locate in windy/sunny sites. This article identifies the various distortions and proposes an auctioned contract to address location and dispatch distortions: a financial Contract for Difference (CfD) with hourly contracted volume proportional to local renewable output/MW, with a life specified in MWh/MW, with long-term transmission contracts based on predicted output-weighted actual or simulated nodal prices. This yardstick CfD delivers efficient dispatch. It assures but limits the total subsidy. It does not over-pay for windy/sunny sites. The revenue assurance allows high debt:equity, dramatically lowering the subsidy cost.

Opportunities for the Growth of the Agro-Industrial Complex Economy with the Negative Dynamics of External Development Conditions

The options for adapting the agro-industrial complex of the Russia to the EU bans on the import of high-tech equipment, machinery, elite seeds, and productive livestock, which are unfavorable for its economy, are analyzed. Among the possible adaptive versions of the development of the development direction, there are cases of agrarian reform that have not been implemented before. Their main goal is to prevent the decline and rise in prices in the changed conditions of production in the economy. It is possible to adjust the practice and state support of agricultural labor by financing the largest areas of development of agricultural enterprises – ​road construction, energy supply, public amenities, and development of inter-district markets for products and means of production, increasing the amount of rental income received at the location. Recommendations are formulated to expand and reduce the cost of meat and dairy products production in the non-chernozem (non-black soil) zone by including abandoned meadows and pastures in the economic turnover. Financing of this expansion is also possible from the means of state support for enterprises with the simultaneous development of the interregional labor market.

The 19th FRAME Annual Lecture, November 2022: Safer Chemicals and Sustainable Innovation Will Be Achieved by Regulatory Use of Modern Safety Science, Not by More Animal Testing.

The decisions we make on chemical safety, for consumers, workers and the environment, must be based on the best scientific data and knowledge available. Rapid advances in biology, in cell-based technologies and assays, and in analytical and computational approaches, have led to new types of highly relevant scientific data being generated. Such data enable us to improve the safety decisions we make, whilst also enabling us to avoid animal testing. Stimulated by the UK and EU bans on animal testing for cosmetics, Next Generation Risk Assessment (NGRA) approaches, which integrate various types of non-animal scientific data, have been established for assessing the safety of chemical ingredients used in cosmetics and other consumer products. In stark contrast, the chemicals regulations in Europe and other parts of the world have not kept pace with modern safety science and regulators are now mandating even more animal testing. Urgently closing this science-regulation gap is essential to upholding the EU's legislative requirement that any animal testing is a last resort. The ongoing revisions of UK and EU chemicals strategy and regulations provide an opportunity to fundamentally change the design and assessment paradigm needed to underpin safe and more sustainable innovation, through applying the best science and tools available rather than continuing to be anchored in animal tests dating back many decades. A range of initiatives have recently been launched in response to this urgent need, in the UK as well as in the EU.

Economic impacts of biodiesel policy in Indonesia: a computable general equilibrium approach

The Government of Indonesia has been promoting the advancement of the biodiesel sector to fulfill its commitment to support clean energy, energy security, and rural development. This paper examines the economic impact of the biodiesel sector using a computable general equilibrium model. Besides analyzing the impacts on the national macroeconomic conditions, other sectors, and household incomes, our model has also included a regional block to capture the impact of the biodiesel mandate on regional growth. Two simulations were performed: (1) fulfillment of the 30% biodiesel blending target (B30 mandate), and (2) Simulation 1 combined with the European Union's biodiesel trade ban resulting in an export reduction of 5.18%. The results show that the two simulations provide positive impacts on macroeconomic variables, including real gross domestic product and real wages. However, the B30 mandate and the combined effect of the EU trade ban still yield an inflationary effect in the short term. They also potentially reduce the production of several agricultural products—such as sugarcane, fruits, vegetables, and soybeans—leading to an increase in food prices. The policy implications highlight that the current B30 mandate and EU ban cannot automatically improve the fuel trade balance.

EU Cross-border carbon tax: conflicting signals for metallurgy

The subject of the analysis is the EU initiative to introduce the so-called Border Carbon Correction Mechanism (CBAM), developed within the framework of the "European Green Course" adopted in 2019 from the point of view of the interests of the Russian ferrous metallurgy. The author analyzes the CBAM rules and procedures developed by the European Commission, including the commodity nomenclature of carbon-taxable ferrous metallurgy products. An assessment of the positions and interests of the European ferrous metallurgy industry in relation to CBAM and the actions of the industry lobby in the course of promoting this initiative is given. The conclusion is made about the achieved narrowing of the intended scope of the CBAM in terms of the covered industries and types of gases and about the extension of the timing of the mechanism's entry into force. The positions of such major global players as China, India, Brazil, African and South-East Asian countries are analyzed in relation to CBAM and prospects for the transformation of this initiative in the current situation are outlined. In connection with the EU ban on the import of Russian ferrous metallurgy products, recommendations are given to Russian metallurgical companies on possible steps to track the details of the promotion of the CBAM initiative. The article was prepared based on the results of research carried out at the expense of budgetary funds under the state assignment to the Financial University under the Government of the Russian Federation.

Tobacco product menthol and flavour bans: their utility for LMIC and lessons from the EU ban

Abstract Background Flavoured tobacco products increase smoking uptake and create dependence. By June 2020 all cigarettes with a characterising flavour, including menthol were banned across the EU, UK and Moldova but many low and middle income countries (LMIC) are yet to develop and implement bans despite high smoking prevalence. This paper has two objectives: to establish whether (1) flavoured tobacco products are present and marketed in LMIC and (2) the experience of bans in Europe can guide development of legislation elsewhere. Methods Research involved analysis of menthol/flavour market data, review of academic and commercial literature and online media. Results The median menthol/capsule market share of the cigarette market grew significantly in middle income countries (p < 0.05) between 2005 and 2019, both in lower and upper middle-income countries [lower: 2.5% (IQR: 0.5-4.0) to 6.5% (IQR: 3.6-15.9); and upper: 4.0% (IQR: 0.8-9.8) to 12.3% (IQR: 3.5-24.3)]. No market data were available on low-income countries, but the academic literature suggested high prevalence of menthol use in Zambia. Tobacco industry strategies underpinning growth of menthol/flavoured tobacco use in LMICs included in-store marketing and display, colourful packs and non-conventional flavour names. Tobacco industry attempts to circumvent the EU ban included introducing new flavoured tobacco products and accessories not included in the ban and exploiting the ban on characterising flavour (as opposed to an ingredient ban) by introducing cigarettes with lower levels of menthol. Conclusions Banning flavoured and menthol cigarettes in LMIC would impact a growing proportion of smokers in these countries. From the European experience, menthol and flavour bans that include all tobacco products and accessories and ban flavour as an ingredient rather than a characterising flavour is recommended. Currently, lack of marketing bans and standardised packaging in LMICs exacerbate the impact of flavours. Key messages

Preliminary evaluation of Solstice® PF as a replacement carrier solvent for Australian fingermark detection

HFE-7100 is a routine carrier solvent in amino acid-sensitive fingermark detection reagents such as ninhydrin and 1,2-indanedione/zinc chloride (IND/Zn). However, a potential EU ban on hydrofluoroethers may require reformulation of these treatments worldwide. Solstice® PF has shown promise as a replacement for HFE-7100 in the United Kingdom. However, the performance (and hence optimal formulation) of IND/Zn is impacted by differences in climate and substrate composition, necessitating assessments under local conditions for different regions. We present a series of preliminary investigations in an Australian context, using the IND/Zn formulation used by Australian forensic service providers. The general performance of Solstice® PF-based IND/Zn was comparable to that using HFE-7100 on three substrate types, three ageing periods (1, 7 and 30 days) and 5 donors. However, slight differences in colour and luminescence intensity, as well as increased ink diffusion, suggest chemical interactions with other reagent components that may affect stability. Specifically, Solstice® PF-based reagent formed a precipitate within a month of storage, though this did not affect performance over a 4 month period. HFE-7100-based IND/Zn was found to be marginally more effective than Solstice® PF when applied to incidental fingermarks. These results indicate that Solstice® PF is a satisfactory alternative carrier solvent to HFE-7100 in an Australian context, though users should be aware of possible limitations regarding compatibility with other evidence components (particularly inks) and shelf-life.

The study on contamination of bottom sediments from the Odra River estuary (SW Baltic Sea) by tributyltin using environmetric methods

We present the first comprehensive study on the occurrence of tributyltin (TBT) in the Odra River estuary (SW Baltic Sea) that encompasses both densely populated and urbanized agglomeration Szczecin city, and sparsely populated biosphere reserves “Natura 2000”. Relationship between TBT and physicochemical parameters of bottom sediments such as granulometry total organic carbon (TOC), total nitrogen (TN), acid volatile sulfide (AVS), As, and metals: Ba, Cd, Co, Cr, Cu, Fe, Hg, Ni, Mn, Mo, Pb, Sn, and Zn was investigated in 120 samples collected in 2017 and 2018. The highest TBT concentrations were over 3000 ng g−1 (dry weight). They were observed in samples collected in the vicinity of the ship maintenance zones of the Szczecin city. Despite the EU ban on its use since 2003, TBT is still present in the environment. Environmetrics analyses such as correlation, cluster, and principal component analysis of obtained results revealed that the main source of sediments contamination by TBT, metalloids, and metals is likely related to the maritime industry: shipyards, ship maintenance as well as ports and marines. TBT is still present in the bottom sediments because of its emission to the environment with dust and paint chips formed during sandblasting cleaning of ship surfaces. The pollutant is further transported with water current to remote localization in the Szczecin Lagoon. Slow water exchange between the Szczecin Lagoon and the Baltic Sea favors accumulation of pollutants in the lagoon sediments. Therefore, it is necessary to implement environmentally friendly methods into ship maintenance and management of the materials from dredged waterways, harbors, and marinas.

Active Power Control of Retrofit LED Tube Lamps for Achieving Entitled Energy Savings in View of the EU Ban on Mercury

The performance of commercially available retrofit LED tubes intended for the replacement of linear fluorescent lamps is measured and analyzed with respect to “real-world” installed electronic ballasts, as ascertained through field recovery from installed bases, such as office buildings, parking garages, and industrial installations in western Europe from 2018 to 2020. Results show a wide variation in lamp power draw, which not only thwarts the energy-saving and climate protection aspects of the LED retrofit solution but also poses potential safety risks. Given the EU’s goals under the Restriction of Hazardous Substances (RoHS) directive to phase out mercury-containing fluorescent lighting, starting from September 2023, the situation is alarming. We show that this lamp power spread is due to the fundamental differences in impedance between fluorescent lamps and LEDs, in combination with the passive nature of the driver electronics that are currently employed in commercially available LED tube lamps. In response to this disparity, a novel driver topology including active power control (APC) is introduced, which shows that the power-spread problem can be avoided, and we offer a manufacturable solution. A prototype retrofit LED tube lamp incorporating this APC driver technology is shown to deliver safe and predictable energy savings, outlining a path toward guaranteeing the expected return-on-investment and positive environmental impact of the solid-state lighting replacement of mercury-containing linear fluorescent lamps.

Effects of chronic exposure to the new insecticide sulfoxaflor in combination with a SDHI fungicide in a solitary bee

The recent EU ban of the three most widely used neonicotinoids (imidacloprid, thiamethoxam and clothianidin) to all outdoors applications has stimulated the introduction of new insecticides into the market. Sulfoxaflor is a new systemic insecticide that, like neonicotinoids, acts as a modulator of nicotinic acetylcholine receptors. In agro-environments, bees can be exposed to this compound via contaminated pollen and nectar for long periods of time. Therefore, it is important to assess the potential effects of chronic exposure to sulfoxaflor, alone and in combination with fungicides, on pollinators. In this study, we tested the effects of chronic exposure to two field concentrations of sulfoxaflor (20 and 100 ppb) alone and in combination with four concentrations of the fungicide fluxapyroxad (7500, 15,000, 30,000 and 60,000 ppb) on syrup consumption and longevity in females of the solitary bee Osmia bicornis L. Exposure to 20 ppb of sulfoxaflor, alone and in combination with the fungicide, stimulated syrup consumption, but did not affect longevity. In contrast, syrup consumption decreased in bees exposed to 100 ppb, all of which died after 2–6 days of exposure. We found no evidence of synergism between the two compounds at any of the two sulfoxaflor concentrations tested. Comparison of our findings with the literature, confirms that O. bicornis is more sensitive to sulfoxaflor than honey bees. Our results highlight the need to include different bee species in risk assessment schemes.

Safety assessment of commercial antimicrobial food packaging: Triclosan and microplastics, a closer look

Antimicrobial food packaging incorporating triclosan (TCS) was banned in the European Union in 2010, while in other countries; regulations on the use of TCS in food contact materials are unclear. In this context, this work has investigated compliance with the EU ban on TCS in commercial antibacterial polypropylene food containers sold through online sales platforms.TCS was present in all food containers tested. Migration studies to food simulants, under different conditions (e.g., conventional and microwave heating, single and repeated use) have been performed according to Regulation 10/2011. The highest TCS migration levels corresponded to 95% ethanol at 40 ºC for 10 days, although migration rates varied between different containers. Furthermore, microplastics were found to leach from the surface of antibacterial food containers when exposed to microwave heating or oven heating. Therefore, microplastics containing TCS might enter food in contact with the containers during use, posing a potential health risk for consumers.

A novel duplex ddPCR assay for detection and differential diagnosis of Ascaridia galli and Heterakis gallinarum eggs from chickens feces

Since the EU ban on battery cages, many studies have listed Ascaridia galli and Heterakis gallinarum as the most common roundworms in the European laying hen population. A complicating factor is that the eggs of these parasites are almost identical. Thus, lack of molecular diagnostic approaches has driven epidemiological studies to take on necropsy for species discrimination, which is labor and cost intensive. Here, we describe a novel diagnostic tool based on droplet digital PCR for simultaneous identification and absolute quantification of the eggs of both of these ascarids in chickens’ droppings using two different genus-specific primer-probe sets targeting the second internal transcribed spacer region (ITS-2) in the nuclear ribosomal (rRNA) gene array. No cross-reaction was observed when different combinations of DNA and species-specific primers and probes were tested. The lowest obtained frequency threshold for the detection of H. gallinarum in the presence of a constant A. galli DNA concentration was determined to be 0.8 %. After validation, we used the assay to analyze field samples collected from several Swedish laying hen farms. Out of 134 samples, 86 (64 %) were positive for A. galli while 11 (8.3 %) samples were positive for H. gallinarum. These samples were initially analyzed with flotation technique for detection of ascarid eggs. The results of the Cohen’s kappa indicated substantial agreement (85.8 %) between the two tests. In conclusion, we have validated a novel molecular-based diagnostic tool for quantification and differentiation between intestinal parasites of major importance in chickens with high precision. Although this study focuses on identification of parasites of laying hens, the findings may well have a bearing on all types of chicken production systems. The present study lays the groundwork for future research into epidemiology of these two important chicken parasite species.

Long-term monitoring of Nucella lapillus imposex in Ria de Aveiro (Portugal): When will a full recovery happen?

Nucella lapillus imposex has been monitored in Ria de Aveiro (Portugal) in order to understand the evolution of organotin (OT) pollution after the EU ban on OT-based antifouling systems (OT-AFS). A rapid decrease of imposex occurred, but a countercurrent tendency upsurged recently (2018–2019) with a slight increase of imposex at some sites, instead of a continuous decline towards a complete recovery. In 2018 the vas deferens sequence index ranged between 0.6 and 1.0 across stations and the percentage of females with imposex varied from 63 to 100%. In 2019 these parameters varied between 0.4 and 1.0 and 37–100%, while the concentration of butyltins (TBT, DBT, MBT) in the dogwhelk tissues were < 1 ng Sn g-1 dw. Although N. lapillus imposex levels are low they are indicative of OT pollution. The full recovery of N. lapillus imposex in the future is uncertain and a cause for concern.

The Virus Yellows Epidemic in Sugar Beet in the UK in 2020 and the Adverse Effect of the EU Ban on Neonicotinoids on Sugar Beet Production

Virus yellows, the disease that was regarded as the worst scourge of sugar beet production in northern Europe in the 20th century, made a dramatic and devastating comeback in 2020, infecting up to 100% of some fields in the Fens of Cambridgeshire, and culminating in 38.1% infection of the national crop, the highest incidence of this pernicious disease since the epidemics of 1974–1976. The causes of the latest epidemic were the consequences of a perfect storm – high overwintering survival of the principal vector, the peach potato aphid, Myzus persicae, following a very mild winter, that resulted in early migration of infective aphids from overwintering hosts into newly emerging beet crops in April. These events, coupled with removal by EU dictate of the most efficient method of controlling the disease, namely the neonicotinoid seed treatments that had kept it under control for the previous 26 years, and the depletion of alternative insecticide spray products, either due to other bans, or having been rendered ineffective by the development of resistance in the vectors, meant that growers were fighting a losing battle almost from the day they sowed their seed. This article examines in detail how the 2020 epidemic developed, and the impact it had on the profitability of the sugar beet industry in the UK, and other parts of Europe. We also argue for a return of neonicotinoid seed treatments in future years to provide more effective control of future pandemics, and thus maintain the presence of this important break crop in arable rotations.

Fermentation of Feed Ingredients as Potential Strategy to Improve Health Status and Reduce Opportunistic Pathogens in Fish Farming

The rapid increase in fish farming has been affected by outbreak of diseases and erratic feed costs. These challenges have stimulated increase in the use of antibiotics to rear fish. Unfortunately, excessive use of antibiotics inhibits or kills beneficial gut microbiota and makes antibiotic residues to accumulate in fish products, which are harmful for human consumption. The use of biological strategies has therefore, been adopted to improve health status, growth performance and reduce predisposition of fish to diseases. This has become necessary in view of the EU ban on most antibiotics used as growth promoters in animal husbandry due to their roles in the production of antibiotic resistant bacteria. Moreover, use of the natural fermentation process, which utilizes functional and safe microbes to transform large and potentially harmful chemical constituents in fish feed to less harmful or safe states have been contemplated in aquaculture. In the present review, lactic acid bacteria (LAB) activity during feed fermentation to mediate positive effects in farmed fish is highlighted, including; modulation of gastrointestinal pH, production of bacteriocins, competitive inhibition and translocation of pathogenic bacteria in the GIT. Other potentials of fermentation to promote feed efficiency and growth performance in fish are also discussed.