The alarming increase in the incidence of melanoma in most affluent countries in recent decades has produced a well-overdue resurgence of interest in this tumor. The literature on melanoma is amassing at inimitable speed. Dermatologists will find it more and more difficult to keep abreast of the many advances in knowledge concerning melanoma of the skin. The purpose of this issue is to document current information relating to the epidemiology, etiology, and prevention of cutaneous melanoma.