This study aims to obtain the concrete example design of the learning outcomes based on internalization of synergy between the CHAMPION core values of Universitas Katolik Musi Charitas with KKNI of Ergonomics and Works System Design courses in Industrial Engineering Department. The CHAMPION core values are Charity, Humanity, Altruism, Managing-capacity, Persistence, Integrity, Open-minded, and Novelty. Internalization of CHAMPION core values in semester learning plans for ergonomics courses will provide distinctive features that differentiate them from other universities. The application of ergonomics that is synergized with the CHAMPION core values is very possible to produce the work system design of teaching and learning process that are reviewed systemic, holistic, interdisciplinary and participatory so that it has an impact on effective, confortable, safe, healty, efficient. Based on the research results, impact on learning outcomes; attitudes and values is 29,58%, general skills is14,79%, special skills is 33,80%, dan knowledge mastery is 21,83%. Three great interesting learning methods are; student centered learning is 39,47%, interaction / group discussion is 32,89%, and project based is 27,63%. Learning experience; task is 29%, compile papers is 27%, doing practice is 20%, survey or visit is 16%, and comparative study is 8%. Assesment criteria / rubric; assignment test as courses, projects, portfolios is 35,9%, written test is 30,9%, performance test is 16,9%, observation test is 7%, and participation test is 2,8%. Based on the data above designed a Semester Learning Plan for Work System Design and Ergonomics courses based on CHAMPION core values.