The planted tree sector in Brazil plays a significant role in the national economy, driven by technological advancements in forestry machines, especially in harvesting. The interaction between operators and machines has become essential for improving performance and ensuring occupational health. This study analyzed forest harvesting machine operators, focusing on anthropometric surveys and proposing indicators for ergonomic satisfaction and cabin layout. Conducted between May 2022 and July 2023 in a northeastern Brazilian forestry company, data were collected during mechanized harvesting of a six-year-old Eucalyptus spp. stand using the cut-to-length system. A questionnaire was applied to 111 employees to assess their ergonomic satisfaction and health. Two indices were created: the Ergonomic Satisfaction Coefficient and the Occupational Health Coefficient. The anthropometric analysis evaluated operators’ percentiles and BMI, revealing that 77.77% were overweight, highlighting the need for health protection measures. The ergonomic indices proved effective in assessing operator satisfaction. The study also determined an adequate workstation layout for the sample group. From the Ergonomic Work Analysis perspective, FW2 and HV3 machines received a good rating based on the adopted parameters.