Epidemiology Of Female Breast Cancer Research Articles

Social epidemiology of female breast cancer in the region of Varna-Bulgaria in 2013-2021 – A retrospective study

Background Female breast cancer remains the most common malignant disease and a leading cause of death worldwide. We aim to follow up on the annual dynamics of its incidence, prevalence and mortality rates in the region of Varna, Bulgaria. Methods Data for the recent retrospective analyses was accessed through the information system of Marko Markov Specialized Hospital for Oncological Diseases of Varna for 2017-2021 and two most recent publications for 2013-2017, in accordance with the Medical University-Varna Ethical committee guidelines. Results The total number of newly registered cases of breast cancer in women aged between 24 and 95 years amounted to 1,341. Mean crude incidence rate in 2017-2021 was 108.83 per 100,000, ranging from 119.89 to 105.25 per 100,000 in 2017 and 2020, respectively. The age group of 61-70 years was most affected (26.55% of the cases). Mean crude prevalence rate during this period was 1496.32 per 100,000, varying from 1447.75 to 1549.71 per 100 000 in 2017 and 2020, respectively. The total number of deaths until the end of 2022 reached 310 with 2018 being the greatest in mortality rate (30.22% of the cases). In 2017-2021, bilateral breast cancer was diagnosed as synchronous in 15 women and metachronous in 9 women. Conclusions The regular regional epidemiological investigations could contribute to the enhancement of the effectiveness and quality of prevention, timely diagnosis and adequate complex treatment.

Global Burden of Female Breast Cancer: Age-Period-Cohort Analysis of Incidence Trends From 1990 to 2019 and Forecasts for 2035

IntroductionThis study aimed to describe the latest epidemiology of female breast cancer globally, analyze the change pattern of the incidence rates and the disease’s association with age, period, and birth cohort, and subsequently present a forecast of breast cancer incidence.MethodsData for analysis were obtained from Global Burden of Disease (GBD) Study 2019 and World Population Prospects 2019 revision by the United Nations (UN). We described the age-standardized incidence rates (ASIRs) from 1990 to 2019 and then calculated the relative risks of period and cohort using an age-period-cohort model, and predicted the trends of ASIRs to 2035.ResultsIn 2019, the global incidence of breast cancer in women increased to 1,977,212 (95% uncertainty interval = 1 807 615 to 2 145 215), with an ASIR of 45.86 (41.91 to 49.76) per 100 000 person-year. Among the six selected countries facing burdensome ASIRs, only the USA showed a downward trend from 1990 to 2019, whereas the others showed an increasing or stable trend. The overall net drift was similar in Japan (1.78%), India (1.66%), and Russia (1.27%), reflecting increasing morbidity from 1990 to 2019. The increase in morbidity was particularly striking in China (2.60%) and not significant in Germany (0.42%). The ASIRs were predicted to continue to increase globally, from 45.26 in 2010 to 47.36 in 2035. In most countries and regions, the age specific incidence rate is the highest in those aged over 70 years and will increase in all age groups until 2035. In high-income regions, the age specific incidence rates are expected to decline in women aged over 50 years.ConclusionsThe global burden of female breast cancer is becoming more serious, especially in developing countries. Raising awareness of the risk factors and prevention strategies for female breast cancer is necessary to reduce future burden.

English

Breast cancer (BC) is a public health concern in sub-Saharan Africa with rising incidence and mortality. In Niger, BC is identified as the leading cancer morbidity and mortality within female population. Its epidemiological literature remains limited or not structured. The aim of this work was to summarize evidence in relation to epidemiology of female breast cancer in Niger. The idea was to know how much was published and available on the topic and what the gaps are. This review was conducted by considering all articles published on the epidemiology of breast cancer in Niger using The PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) model. A comprehensive search of material was performed using PubMed/Medline, African Journals Online, (AJOL), Web of Science, Google Scholar and Scopus/Elsevier. In total, 16 articles were initially screened, 14 full text articles were accessed for eligibility and 6 were included in the final review. None of the screened papers had clinical trial methodology or survival analysis. Moreover, no peer reviewed paper was found on breast cancer screening. The output of this review pointed out sustainable gaps in the field of epidemiology and public health research on BC in Niger. The country should have a national screening program and an updated analysis of cancer registry data. Effort is to be done on studies about cancer survival, feasibility and acceptability of alternative screening methods adapted to low-income countries, such as Niger. Key words: Niger, breast cancer, public health, screening.

Epidemiology of Female Breast Cancer in West Jakarta, Indonesia

Background: Breast cancer was the most common cancer in the world. GLOBOCAN 2012 estimated the incidence of female breast cancer in Indonesia was 40.3 per 100,000 and the mortality rate was 16.6 per 100,000. In 2016, Dharmais National Cancer Center was appointed as Regional Population Based Cancer Registry in West Jakarta. West Jakarta was a municipality with 2,281,945 populations, being the 2nd largest population in DKI Jakarta Province. Aim: This study was to evaluate the quality of population based cancer registry data and to describe the epidemiology of female breast cancer in West Jakarta, Indonesia during 2008-2012 and to compare with GLOBOCAN 2012 . Methods: We used population based cancer registry data with ICD - O code C50.0-C50.9 in female who live in West Jakarta. The population based cancer registry data were collected in Dharmais National Cancer Center. We evaluated the quality of population based cancer registry data based on WHO-IARC rules for cancer registry data. Results: The quality of population based cancer registry data were microscopic verification (70%); DCO percentage (20.8%), and unknown age (0%). The trend of female breast cancer was increasing during 2008-2012. Age-standardized rate incidence was 19.3 per 100,000. The most of frequent were in 45-49 years old, not other specific location subtopography (81.5%), the histopathology type was ductal and lobular neoplasm (51.8%), in stage III (44%), and with metastases to bone (34%). The average of length of duration was 29.1 months, most of them were unknown of last status contact (84%). Conclusion: The coverage and quality data of West Jakarta population based cancer registry need to be increased and establish a follow-up system to decrease the unknown last contact status of patients.

Epidemiology of Female Breast Cancer in Ogun State: Intra- and Inter-regional Discuss

This study determined the prevalence of breast cancer in relation to age, reproductive status and population of Ogun State. Out of a total of 816 human cancer presentations observed between 2012 and 2016, 334 (40.9%) female breast cancer (with age range= 23 to 95 years and mean age= 50.3 years) were retrospectively reviewed. Result revealed five breast cancer types: Invasive ductal carcinoma (IDC), ductal carcinoma in situ (DCIS), Paget cell disease, medullary carcinoma and mucinous carcinoma. Invasive ductal carcinoma was the predominant breast cancer type (94.9%) while year 2016 had the highest number of breast cancer presentations (47%) at p<0.001). Result also showed that age range of 41-50 years and 61-70 years had the highest prevalence and incidence of breast cancer, respectively (p<0.001). Reproductive age (23-45 years) had the highest frequency of invasive ductal carcinoma and Paget cell disease when compared with other age groups (p<0.001). Result also showed interesting differences in prevalence of breast cancer types in Ogun State compared with other regions. The result revealed that IDC, DCIS, Medullary carcinoma, Mucinous carcinoma and Paget's cell disease are more prevalent in South-West, South-East, North-West, South-East, North-Central regions, respectively. In conclusion, our findings suggest that breast cancer occurrence is greatly influence by age, reproductive status and location.

The Descriptive Epidemiology of Female Breast Cancer: An International Comparison of Incidence, Survival and Mortality.

The Descriptive Epidemiology of Female Breast Cancer: An International Comparison of Incidence, Survival and Mortality.

P133 Evocative epidemiology of female breast cancer in Delhi, India

P133 Evocative epidemiology of female breast cancer in Delhi, India

The descriptive epidemiology of female breast cancer: An international comparison of screening, incidence, survival and mortality

BackgroundThis paper presents the latest international descriptive epidemiological data for invasive breast cancer amongst women, including incidence, survival and mortality, as well as information on mammographic screening programmes. ResultsAlmost 1.4 million women were diagnosed with breast cancer worldwide in 2008 and approximately 459,000 deaths were recorded. Incidence rates were much higher in more developed countries compared to less developed countries (71.7/100,000 and 29.3/100,000 respectively, adjusted to the World 2000 Standard Population) whereas the corresponding mortality rates were 17.1/100,000 and 11.8/100,000. Five-year relative survival estimates range from 12% in parts of Africa to almost 90% in the United States, Australia and Canada, with the differential linked to a combination of early detection, access to treatment services and cultural barriers. Observed improvements in breast cancer survival in more developed parts of the world over recent decades have been attributed to the introduction of population-based screening using mammography and the systemic use of adjuvant therapies. ConclusionThe future worldwide breast cancer burden will be strongly influenced by large predicted rises in incidence throughout parts of Asia due to an increasingly “westernised” lifestyle. Efforts are underway to reduce the global disparities in survival for women with breast cancer using cost-effective interventions.

Breast Cancer MichellMichael Cambridge, UK Cambridge University Presspp. 268 2010ISBN: 978-0-521-51950-2

Free AccessBook reviewBreast CancerA K BanerjeeA K BanerjeeSearch for more papers by this authorPublished Online:5 Mar 2014https://doi.org/10.1259/bjr-83-993-808aSectionsPDF/EPUB ToolsAdd to favoritesDownload CitationsTrack Citations ShareShare onFacebookTwitterLinked InEmail AboutThis volume is the latest in the series of multidisciplinary monographs on contemporary issues in cancer imaging. Breast cancer is the commonest cancer affecting women worldwide. Over the past 20 years, it has been a high profile health issue in western nations, with regular media coverage and debate over breast cancer screening programmes for this much-feared condition.This book takes a very multidisciplinary approach to the subject of breast cancer and is a valuable contribution for all those who are involved with this disease. Since Leborne’s early work on mammography, diagnostic imaging in breast disease has continued to develop at a rapid pace. In the past 20 years, with the advent of screening and improved techniques such as digital mammography, ultrasound and newer techniques such as MRI, imaging and management of the disease has almost altered beyond recognition.In this multi-authored text, all aspects of this disease are covered, including epidemiology, pathology and treatment. The chapter on the epidemiology of female breast cancer is a particularly useful introduction to the risk factors for this condition. A book like this could not ignore the subject of breast screening and this is dealt with succinctly, while still including the relevant statistical information.Other chapters cover advances in x-ray mammography, breast ultrasound and MRI imaging. Pathological contributions are not given short shrift. Current issues around the pathology of duct carcinoma in situ are discussed and the difficulties involved are made clear. There is an excellent chapter on the radiological assessment of the axilla and also newer techniques, such as positron emission tomography and its role in the assessment of breast cancer. The final chapter covers the advances in the adjuvant treatment of early breast cancer.Overall, the multidisciplinary discussion of breast cancer is highlighted in this book and everyone involved in the diagnosis and management of these patients would benefit from reading this volume. I found this book extremely useful; it is up-to-date and extensively referenced. It is not solely about diagnostic imaging and, as such, will appeal to all members of the multidisciplinary team involved in looking after patients with this disease. Previous article Next article FiguresReferencesRelatedDetails Volume 83, Issue 993September 2010Pages: 723-e197 2010 The British Institute of Radiology History Published onlineMarch 05,2014 Metrics Download PDF

Epidemiology of Male Breast Cancer

AbstractBreast cancer in men is a rare disease, accounting for ∼1% of all breast cancer cases. Although the epidemiologic literature regarding female breast cancer is extensive, relatively little is known about the etiology of male breast cancer (MBC). This review is intended to summarize the existing body of evidence on genetic and epidemiologic risk factors for breast cancer in men. Overall, the epidemiology of MBC presents similarities with the epidemiology of female breast cancer. Major genetic factors associated with an increased risk of breast cancer for men include BRCA2 mutations, which are believed to account for the majority of inherited breast cancer in men, Klinefelter syndrome, and a positive family history. Suspected genetic factors include AR gene mutations, CYP17 polymorphism, Cowden syndrome, and CHEK2. Epidemiologic risk factors for MBC include disorders relating to hormonal imbalances, such as obesity, testicular disorders (e.g., cryptorchidism, mumps orchitis, and orchiectomy), and radiation exposure. Suspected epidemiologic risk factors include prostate cancer,prostate cancer treatment, gynecomastia, occupational exposures (e.g., electromagnetic fields, polycyclic aromatic hydrocarbons, and high temperatures), dietary factors (e.g., meat intake and fruit and vegetable consumption), and alcohol intake.

Descriptive epidemiology of female breast cancer in Tianjin, China

Objective To observe trends in the changes of incidence and mortality of female breast cancer patients in Tianjin, and evaluate the effect of these trends on prevention.

Genetic epidemiology of female breast cancer

Population-based studies of the genetic epidemiology of female breast cancer have shown that only a small proportion of familial aspects of the disease can be explained by what is currently known about its causes. These include mutations in the genes BRCA1 and BRCA2, associated with a 10- to 20-fold increased risk of developing breast cancer. There may be genetic or environmental factors that modify cancer risks in mutation carriers, not necessarily in the same way as they do in non-carriers. The ‘typical BRCA1/2 family’ consists of a ‘sporadic case’, not a multiple-case family. There are likely to be other dominantly- and even recessively-inherited genetic risks, including those influencing intermediate markers like mammographic densities. Unravelling all the causes of familial aggregation will be a major step in understanding the causes of female breast cancer.

Review article: epidemiology of male breast cancer. A meta-analysis of published case-control studies and discussion of selected aetiological factors.

Male breast cancer is a rare tumour in all parts of the world. About 1% of all breast cancers occur in men, but the male/female ratio is higher among black than among white populations. This effect can be seen in US cancer registries and even more markedly in African data. A positive correlation exists on a population scale between male breast cancer and prostate cancer. Seven case-control studies of male breast cancer are available, and a pooled analysis was conducted of the most commonly suspected risk factors. Male breast cancer appears to be associated with marital status: Mantel-Haenszel exposure odds ratio (EOR) for never married = 1.6; 95% confidence limits (CL) = 1.1, 2.3, religion (EOR for being Jewish = 2.1; 95% CL = 1.4, 3.2), previous breast pathology (EOR for positive history of benign breast disease = 2.7; 95% CL = 1.7, 4.2), gynaecomastia (EOR for positive history = 6.2, 95% CL = 3.4, 11.4), previous testicular pathology (EOR for positive history = 2.2; 95% CL = 1.5, 3.3), previous liver diseases (EOR for positive history = 1.6; 95% CL = 1.0, 2.4) and family history of breast cancer (EOR for first-degree relative with breast cancer = 2.5; 95% CL = 1.7, 3.7). No association is found with smoking history. Other potential risk factors such as reproductive history, education, occupation, anthropometric variables, association with various diseases, and specific exposures such as drug use, were not systematically evaluated in all studies and provide sometimes contradictory results, possibly due to small numbers of exposed subjects. Overall, the analytical epidemiology of male breast cancer presents similarities with the epidemiology of female breast cancer, with a potential role of factors related to hormonal status, relative hyperoestrogeny in men being potentially linked to increased risk of disease. Genetics may also play a role, with high risk linked to a familial history of breast cancer, and with a major risk in patients with Klinefelter's syndrome.