Enucleation Of Cyst Research Articles

The efficacy of Nano-crystalline hydroxyapatite combined with parathyroid hormone versus Nano-crystalline hydroxyapatite alone on healing of bone defect after cyst enucleation: a randomized clinical trial (RCT)

The efficacy of Nano-crystalline hydroxyapatite combined with parathyroid hormone versus Nano-crystalline hydroxyapatite alone on healing of bone defect after cyst enucleation: a randomized clinical trial (RCT)

Combined removal of ovarian teratoma and oocyte retrieval by laparoscopic surgery under regional anesthesia

To describe the simultaneous laparoscopic approach for teratoma removal and oocyte retrieval performed under regional anesthesia in a woman, desiring to preserve fertility. The patient included in this video gave consent for publication of the video and posting of the video online including social media, the journal website, scientific literature websites, and other applicable sites. Video case report demonstrating the clinical management and laparoscopicteratoma removal combined with oocyte retrievalaccomplished underregional anesthesia. University tertiary care hospital. We present a case of a 31-year-old woman who referred to our Fertility Center with a previous history of right salpingo-oophorectomy for mucinous ovarian cystadenoma and the presence of a large ovarian teratoma of ten centimeters of the contralateral ovary. The ovarian stimulation started in the early follicular phase. Not being able to visualize follicular growth during the ovarian stimulation, it was decided to adopt fixed protocol with antagonist on the 5th day and to proceed, on 15th day, with a laparoscopic pick-up and simultaneous removal of the cyst. Laparoscopic surgery was performed: the left ovary appeared larger in size for the presence of the suspicious mature dermoid cyst and multiple follicles, previously not identified at ultrasound imaging. The follicles contained oocytes that were aspirated with an aspiration needle of 17 G connected to a craft suction pump. Then, practicing the stripping technique, an enucleation of the ovarian cyst was performed. Surprisingly, the removal of the cyst revealed other follicles that were readily aspirated. The patient remained awake during the entire procedure and a low pressure of 10 mmHg was maintained at 15° of Trendelenburg position. A total of seven follicles were aspirated, seven oocytes were retrieved, and six mature oocytes were cryopreserved. The cyst was totally removed and no intracavitary spillage was caused. Simultaneous laparoscopic approach for teratoma removal and oocyte cryopreservation should be considered an effective fertility preservation strategy in patients in whom the presence of an ovarian neoformation does not allow visualization of growing follicles by ultrasound. Laparoscopic oocyte retrieval under regional anesthesia is a safe and well-tolerated technique and should be considered for patients where the transvaginal approach could not be performed.

Enucleation vs Marsupialization of dentigerous cysts in children

Dentigerous cysts are common developmental odontogenic cysts found in the oral cavity. They are often discovered incidentally on dental X-rays or noticed as asymptomatic swellings. These cysts forms from reduced enamel epithelium that remains attached at the cementoenamel junction around the crown of an unerupted or impacted tooth. Although most dentigerous cysts are developmental, in young patients, they may also arise due to inflammation, often arising from decay in the primary teeth. Treatment options for dentigerous cysts range from marsupialization to complete removal, depending on the effect of the cyst on surrounding structures. The loss of a permanent tooth during the treatment of a dentigerous cyst can significantly impact a child's oral development. This article discusses 2 cases of primary teeth associated with cysts and their different treatment options.

Enucleation and Intentional Replantation of Paradental Cyst on The Lingual Side of The Second Molar: A Case Report

Enucleation and Intentional Replantation of Paradental Cyst on The Lingual Side of The Second Molar: A Case Report

Treatment Modalities and Rehabilitation Procedures of Dentigerous Cyst Among the Paediatric Population - A Systematic Review of Case Reports

BACKGROUND: The dentigerous cyst which wraps around the impacted teeth is the most prevalent developmental odontogenic cyst among the Paediatric population in India. Various treatment modalities were proposed previously, such as enucleation, marsupialization, fenestration, or a combination technique with or without preservation of the affected dentition. OBJECTIVES: The aim of the Paediatric dentist should rely on the preservation of permanent teeth. Hence, this systematic review aimed to evaluate the prevalence and describe the different treatment methods and rehabilitation techniques conducted following the surgical excision of dentigerous cysts among the Paediatric population in India, which is significant to Paediatric dentists. METHODS: Systematic review registered under PROSPERO following PRISMA guidelines. Thorough search was done in PubMed, EMBASE, ProQuest and Cochrane Library. RESULTS: The results showed that the dentigerous cyst occurred commonly in the age group of children aged 6 – 10 years (72.22%), with a male predilection (80.56%). The complete cyst enucleation with the removal of milk teeth and permanent dentition (52.78%) was preferred more than the preservation of the affected dentition. After complete enucleation of the cyst in only 57.89% of cases, rehabilitation procedures were planned. The results showed that proper rehabilitation was not planned in many cases, which may lead to poor oral hygiene maintenance and early space loss. CONCLUSIONS: It is important for the Paediatric Dentist to know the importance of preserving the permanent teeth or plan a wise rehabilitation procedure to replace missing teeth to maintain the proper oral health of the children. Keywords: Dentigerous Cyst, Paediatric Dentistry, Enucleation, Marsupialization, Oral Rehabilitation.

Application of topical 5-Fluorouracil to reduce the recurrence of odontogenic keratocyst: A prospective study with 2-year follow-up

ObjectivesThe purpose of this prospective study was to evaluate the effect of topical 5-Fluorouracil as an adjunct therapy in reducing the recurrence of odontogenic keratocyst. MethodsForty-eight patients with proven incisional biopsy as odontogenic keratocyst were included in this clinical study. The patients were divided into two equal groups, the test group patients were treated with 5-Fluorouracil cream after cyst enucleation. However, the control group patients were treated with cyst enucleation only. Recurrence (yes/no) was the primary outcome variable evaluated by clinical signs of inflammation, swelling, or pain within a 2-year follow-up. The pain was measured on a visual analogue scale, and swelling was measured pre-surgically using vertical and horizontal references, 1 week, 1 month, 3 months, 6 months, 12 months, and 24 months. Computed tomography was performed pre-surgically and 24 hours post-surgically, at 12-month, and 24-month intervals to evaluate local bone density. The T-test was used to compare between two studied groups. ResultsPost-surgical follow-up showed uneventful wound healing in both groups with no clinical signs of recurrence or swelling, pain results demonstrated that patients have decreased records throughout the observation periods with no significant difference between both groups. Normal sensation was encountered in all patients except for one patient in the control group who showed no sensation (score 2). Post-surgical radiographic findings revealed a considerable shift in bone density in all patients of both groups at the site of excised lesions during the follow-up periods compared with immediate post-surgical radiographs. However, the test group patients demonstrated a significant increase of bone density between different evaluation periods (P = 0.001) than the control group. ConclusionConservative enucleation of odontogenic keratocyst combined with topical application of 5-Fluorouracil is an effective treatment with lower recurrence rates, less morbidity, and normal bone healing.

Decoding Cystic Lesions in Mixed Dentition through Step-by-step Diagnosis

Abstract Radicular cysts are the most often documented inflammatory cysts in the adult population, although their incidence in children is regarded as unusual. This study presents a 12-year-old female patient, who had an asymptomatic radicular cyst along with a retained and decayed deciduous tooth in the left posterior mandibular area, the cyst. The patient underwent cystic enucleation after a clinical and radiographic evaluation which led to a provisional diagnosis that was corroborated by the histological findings. In this article, the differential diagnosis and treatment of a radicular cyst in a pediatric patient is discussed.

Characteristics of impacted mandibular third molar-related lesions.

This study identifies factors for differential diagnosis among lesions by retrospectively comparing panoramic and cone-beam computed tomography images and analyzing the characteristics of lesions associated with impacted mandibular third molars (IMTs). A retrospective cohort study was conducted in patients who simultaneously underwent IMT extraction surgery and related benign tumor resection or cyst enucleation at our institution from 2017 to 2021. To compare the characteristics of each group, two comparative analyses were conducted. The first comparison considered the most frequently observed lesions associated with IMTs: dentigerous cysts, odontogenic keratocysts (OKCs), and ameloblastoma. The second comparison involved placing dentigerous cysts, which have a relatively low recurrence rate, into group A and placing OKC, ameloblastoma, and odontogenic myxoma, which have high recurrence rates, into group B. Significant differences in the size of the lesion were found in the order of ameloblastoma, OKC, and dentigerous cyst (P <0.05). The buccolingual width of ameloblastoma differed significantly from that of the other groups, with no significant difference observed between the OKCs and dentigerous cysts (P=0.083). Patient age and lesion size differed significantly among lesion types associated with IMTs, with younger age and larger lesions for OKCs and odontogenic tumors. OKCs are likely to have a larger mesiodistal width than dentigerous cysts. The buccolingual width of ameloblastomas was larger than those of dentigerous cysts and OKCs.

Odontogenic cysts in the maxillary sinus: A case series

In this article, we present a series of three patients who reported to the department with different chief complaints. The patients underwent the necessary basic and advanced radiological investigations which showed presence of cysts along with impacted teeth in the maxillary sinus, following which all the patients were subjected to cyst enucleation under GA and the surgical specimens were sent for histopathological examination for definitive diagnosis.

Bone defect reconstruction after radicular cyst enucleation with bovine bone graft and protein rich plasma: A case report

Background: Radicular cyst enucleation and reconstruction with bone graft is a surgical procedure used to remove a cyst that has formed around a tooth root. The procedure involves making an incision in the gum tissue to expose the cyst, removing the cyst and any affected bone, and then filling the resulting defect with a bone graft. The bone graft is typically taken from the patient's own body, such as from the chin or the iliac crest, and is used to promote new bone growth and help stabilize the surrounding teeth. After the procedure, the gum tissue is sutured back into place, and the patient may be prescribed pain medication and antibiotics to help manage any discomfort or infection. The success of the procedure depends on the size and location of the cyst, as well as the patient's overall oral health. Purpose: To aim management of cyst enucleation and reconstruction bone defect with bovine bone graft and protein rich plasma (PRP). Case(s): A female 19 years old with the chief complaint of the patient have caries io the lower left jaw tooth. The patient complains of frequent oedemmon left cheek site. On panoramic radiologic examination, a radiolucent lesion with a radiopaque border was found in the apical region of tooth 36. Case Management: The patient underwent enucleation of cyst and bone defect reconstruction with general anaesthesia. After 14 days, the sutures were removed and the wound were healed. Conclusion: This case of radicular cyst can be used for guideline with enucleation of radicular cyst and bone defect reconstrtion

Comparing the effect of Leukocyte PRF (L-PRF) and Advanced PRF(A-PRF) added to nanohydroxyapatite on osseous regeneration after maxillary cyst enucleation (Randomized controlled trial)

Comparing the effect of Leukocyte PRF (L-PRF) and Advanced PRF(A-PRF) added to nanohydroxyapatite on osseous regeneration after maxillary cyst enucleation (Randomized controlled trial)

Cleidocranial dysplasia associated with dentigerous cyst-review of literature and case report of two siblings.

Cleidocranial dysplasia (CCD) is a developmental anomaly of the skeleton and teeth which may be inherited, be transmitted as dominant characteristics in either male or female or even appear spontaneously. A case was reported in the department of oral medicine and radiology of two sisters age 17 and 19 years old with a chief complaint of milk teeth not falling since childhood. They presented specific physical and oral findings in common which suggested the idea of an undiagnosed syndrome. The sisters showed CCD characteristics including short stature (4 feet) and frontal bone resorption indicating delayed closure of fontanels. The stature is moderately shortened with the neck appearing long and narrow and the shoulders markedly dropped. Dental abnormalities such as retention of primary dentition, multiple supernumerary teeth, and delayed eruption of permanent dentition. OPG showed the presence of multiple impacted permanent and supernumerary teeth with radiolucency involving the crowns of impacted teeth revealing a cystic lesion. Lateral cephalogram also revealed the presence of multiple impacted teeth. The provisional diagnosis of CCD with dentigerous cyst was given. The enucleation of cyst was done and submitted for histopathological examination. Histopathologically, the soft tissue section suggested the features of dentigerous cyst. The final diagnosis of CCD associated with dentigerous cyst was confirmed.

Optimal time to definitive enucleation of large cysts following marsupialization: A single center, retrospective study

ObjectivesOptimal time to enucleation following marsupialization of large odontogenic mandibular cysts is undefined. We aim to assess volume reduction throughout follow-up, to indicate optimal time to enucleation. Secondary objectives include the identification of factors influencing cyst reduction. Study designWe retrospectively enrolled 15 patients with mandibular cysts of different histological types treated with marsupialization at our center between 2018 and 2022. Cyst volume was assessed with cone-beam computed tomography (CBCT) and a semi-automatic segmentation algorithm, at baseline and between 6 and 8 months post marsupialization. ResultsThe overall mean cyst volume reduction percent (VR%) was 57.7 % or 0.2 % per day. VR% at 8 months was significantly higher than those assessed at 6 and 7 months (67.1% vs 47.1 %, p = 0.003). Time to CBCT was the only independent variable influencing cyst VR%. ConclusionOur study proves that the optimal time to enucleation for mandibular cyst is 8 months, independent of histological cyst type, patient age, baseline cyst volume and the number of pre-operative residual bone walls.

Assessment of bone regeneration after maxillary radicular cyst enucleation with or without bone grafting materials: a retrospective cohort study

ObjectiveThe limitations of spontaneous bone healing underscore the necessity for exploring alternative strategies to enhance bone regeneration in maxillary radicular cyst cases. This retrospective study aimed to assess the impact of a bone substitute material (i.e., Bio-Oss) on bone volume regeneration following maxillary radicular cyst enucleation using cone-beam computed tomography (CBCT).Materials and methodsSeventy-three patients with maxillary radicular cysts were divided into two groups: one undergoing guided bone regeneration (GBR) with Bio-Oss and absorbable collagen membrane (n = 35), and the other receiving cyst excision alone (n = 38). Volumetric measurements using Amira software on CBCT scans evaluated bone regeneration, with cystic lesion shrinkage rates calculated. Intergroup comparisons utilized independent sample t-tests (P < 0.05), and linear regression analysis assessed the influence of preoperative cyst volume and group on bone healing.ResultsBoth groups showed similar success rates in bone formation at the 12-month follow-up, with no significant differences between them (mean (SD), control: 75.16 (19.17) vs. GBR: 82 (20.22), P > 0.05). Linear regression analysis revealed a negative correlation between preoperative cyst volume and bone regeneration in both groups (P < 0.05).ConclusionBio-Oss may not significantly enhance bone augmentation in maxillary radicular cysts. In addition, preoperative cyst volume negatively affected the shrinkage rate of cystic lesions.Clinical relevanceClinicians should consider patient-specific factors such as anatomy and lesion size when determining the need for bone substitute materials. Future research could focus on optimizing treatment protocols and alternative regenerative strategies to improve patient outcomes in maxillary cyst cases.

A Unique Clinical Appearance of Upper Maxillary Premolar associated with Dentigerous Cyst: Case Report

During dental development, a variety of hereditary and environmental variables interact to cause dental abnormalities. The etiology may involve multi-tiered, multi-directional, and multi-factorial processes. Fusion is a dental anomaly that happens during tooth development, where two separated teeth bud fuse together to form a single tooth. The morpho-differentiation or histo-differentiation stages of tooth development, genetic and environmental variables can induce developmental dental abnormalities. A clinical resemblance of a "double-headed" maxillary second upper left premolar with two crowns, formed on the both coronal and apical root end or whether it is just a hypercementosis of apical root discovered after surgical extraction and enucleation of cyst. Investigations to confirm such unique findings were performed. This case report discusses the importance of clinical, radiographic and laboratory investigations to confirm the unique appearance of the maxillary second premolar.

MED15::TFE3 fusion renal cell carcinoma with extensive cystic change: A clinicopathologic and molecular genetic study of 2 cases, with an emphasis on differential diagnosis.

TFE3-rearranged renal cell carcinomas (RCCs) harbor gene fusions between TFE3 and 1 of many partner genes. MED15::TFE3 fusion RCC is rare, often cystic, and easily misdiagnosed. This study aimed to characterize 2 cases of MED15::TFE3 fusion RCC with extensive cystic change using fluorescence in situ hybridization and targeted RNA sequencing. Both patients were young adult women aged 29 and 35 years. Radiologically, both presented with a cystic Bosniak category II renal lesion. The cysts measured 9.3 cm and 4.8 cm in greatest dimension. Both patients underwent cyst enucleation, and neither had tumor recurrence or metastasis at 26 and 6 months of follow-up, respectively. Microscopically, both tumors were entirely cystic, with thick, fibrous cystic walls lined by small clusters of cells with clear to eosinophilic cytoplasm and uniform, round nuclei with inconspicuous nucleoli. There were also small aggregations of similar clear cells within the cystic walls. Foci of basement membrane-like material depositions were noted in 1 case; calcifications were observed in both cases. Both cases demonstrated nuclear positivity for PAX8 and TFE3 and cytoplasmic staining for Melan-A; HMB45, CAIX, and CK7 were negative. Fluorescence in situ hybridization revealed that both tumors were positive for TFE3 rearrangements. RNA sequencing identified MED15::TFE3 gene fusions in both cases. The main differential diagnosis of MED15::TFE3 fusion RCC includes multilocular cystic renal neoplasm of low malignant potential and atypical renal cysts. Molecular confirmation of TFE3 fusion is essential for establishing the correct diagnosis.

Maxillary Sinus Augmentation and Implant Installation in Patients With Pseudocysts and Mucous Retention Cysts.

This case study systematically assessed diverse approaches to sinus augmentation in the presence of sinus pathology. Three patients were carefully selected and categorized as pseudocyst (PsC) (type 1), mucous retention cyst (MRC) smaller than 20mm (type 2), and MRC larger than 20mm in size (type 3). All patients underwent sinus augmentation procedures, with each case utilizing a unique surgical approach. Spontaneous drainage was performed for the patient with PsC (type 1), followed by uncomplicated sinus augmentation. For the patient with an MRC smaller than 20mm (type 2), aspiration of the cyst contents preceded sinus augmentation. Conversely, the patient with a larger MRC (type 3) underwent cyst enucleation followed by sinus augmentation after complete recovery of the sinus membrane. No complications were noted in any of the cases, and follow-up revealed stable implant installation at the site of sinus augmentation. Within the constraints of this study, the choice of surgical procedure, whether involving spontaneous drainage, aspiration, or enucleation, should be guided by an anticipated pathologic diagnosis and the size of the sinus cyst. This informed approach empowers clinicians to make well-informed decisions for the best possible outcomes and sustained results. Overall, this study offers valuable insights for clinicians seeking to optimize sinus augmentation procedures in the presence of sinus pathology.

Odontogenic keratocyst involving the maxillary antrum: A case report

Odontogenic keratocyst (OKC) is a benign neoplasm of the jaw with a common occurrence in the mandibular ramus area characterized by aggressive behavior and a high recurrence rate. This lesion rarely occurs in the maxilla. The aim of this report is to discuss the case of a 27-year-old male who suffered from OKC in the left maxillary antrum, which includes surgical management of the case with cyst enucleation and chemical cauterization.

Myoclonic Movement After Mandibular Cyst Enucleation Under General Anesthesia, A rare case report during COVID-19 pandemic

Myoclonic movement is not common side effect after general anaesthesia. Since we use various intravenous agents during general anaesthesia recently, it is troublesome to find out the exact cause of this neurologic complication

Using autogenous tooth sticky bone graft repair mandibular third molar dentigerous cyst osseous defects

BackgroundDentigerous cyst are most common odontogenic cyst and they frequently occur at the mandibular third molar. Their asymptomatic long medical history always resulted in severe bone resorption at the distal aspect of the adjacent second molar. BonMaker® ATB demonstrate an excellent autogenous bone graft candidacy. The aim of this study is to share a single team’s experience of dentigerous cyst osseous defect repairing by applying autogenous tooth sticky bone graft.MethodIn total, 18 patients with dentigerous cyst, which was arised from mandibular third molar unilaterally, were enrolled in this study. Enucleation of dentigerous cyst was performed extracting with involving teeth under general anesthesia. Autogenous tooth sticky bone graft was prepared using extracted tooth and autogenous fibrin glue. Subsequently, grafting was performed above covering with concentrate growth factors. Patients were followed up at sixth months.ResultsThey were eleven male and seven female patients. Their ages ranged from 20 to 40 years, with a mean of 31 years. Primary wound healing of all sites was achieved in all the patients. Sixth months postoperative radiographic assessment show that dentigerous cysts osseous defects of seventeen patients were good bone filling and ossification. One patient occurred slight bone resorption at the distal aspect of the adjacent second molar.ConclusionWithin the limitation of sample size and retrospective nature of the present study, autogenous tooth sticky bone graft demonstrates one of the best alternative alveolar bones repairing graft.