Abstract: Big data, enterprise digitalization, and e-commerce all have one thing in common: they were born from the Internet. Since the onset of the 21st century, the global Internet industry has experienced rapid growth, with e-commerce emerging as a key player. Participants in e-commerce engage with both the global online marketplace and the physical market, utilizing modern communication networks and information technology to conduct business activities through e-commerce platforms or service platforms. E-commerce embodies characteristics such as market globalization, rapid transactions, virtualization, and cost-effectiveness, making it highly favored by enterprises. Presently, e-commerce relies heavily on robust databases, as well as the data collection, processing, and analysis capabilities of big data. This reliance compels traditional enterprises to undergo digital transformation. This study delves into the impact of big data and enterprise digitalization on the e-commerce industry, exploring the mechanisms underlying their influence on cross-border e-commerce. By examining these dynamics, the study aims to provide insights into the evolving landscape of e-commerce and the transformative potential of big data and digitalization in shaping its future trajectory.