Magnetized non-Newtonian models nowadays have attracted many researchers because it is an exciting field in the collaboration of material science, fluid dynamics, and applied physics. Their unique properties and adaptability render them invaluable across various technological and industrial applications, promising further innovations as research advances. This research unveils the intricate rheological and thermal behavior of magnetized non-Newtonian nanofluids undergoing peristaltic motion. The study aims to enhance engineering design techniques for optimal biophysiological performance by incorporating second-order slip, convective conditions, and temperature-dependent thermal conductivity. The Buongiorno nanofluid model is adopted to investigate heat and mass transfer phenomena, while the Prandtl non-Newtonian fluid model is employed to comprehend the complex rheological characteristics of the fluid. A long-wavelength approximation with a low Reynolds number was employed to simplify the governing equations. Analytical solutions have been obtained by solving the nonlinear transformed equations using the Homotopy perturbation technique. The findings are validated with previous literature and indicate that magnetic fields play a key role in controlling peristaltic flow behavior and nanofluid pumping rates. Moreover, the interplay between non-Newtonian rheology and nanofluid parameters significantly affects temperature distribution patterns. An increase in the species Biot number and thermophoresis parameter leads to improved concentration behavior. Conversely, a reversible trend is noted with the augmentation of the Prandtl number, Eckart number, variable thermal conductivity, and Brownian motion parameters. This research provides new insights into magnetohydrodynamic transport mechanisms in peristaltic systems. The modeling approach, coupled with analysis, lays the background for improved fluid circulation, oxygen delivery, waste removal, and nutrient transport in biomedical applications. Specifically, the findings are important for advancing the design of peristaltic pumps tailored for targeted drug delivery and optimizing fluid flow within gastrointestinal tracts.
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