In the modern world, the use of novel technologies in architecture has become highly significant and transformative for human-environment interactions. One of the most critical concerns in architecture is achieving optimal forms and selecting suitable materials for effective design across diverse climatic zones. Also, adopting innovative climate design methods in public spaces, such as educational buildings, is essential due to their strategic urban locations and diverse user populations. Therefore, the research conducted in this study focuses on two main aspects: optimizing building form based on energy consumption and solar radiation received by vertical surfaces, and, selecting appropriate nanomaterials for building surface to reduce energy usage and maintenance costs. This study begins with theoretical foundations, defining the key terms through a comprehensive review of relevant literature. Then, four identical classroom modules with consistent height and floor levels are proposed, and Energy Plus software is used to evaluate the energy consumption based on a module simulation in initial forms of square and rectangle with varying proportions. The best module and orientation is determined using specified climatic data of the coldest and the hottest days of the year. Further, investigations involve combining these modules in various layouts, emphasizing those that align with the functional requirements of educational spaces. Finally, two parameters of energy consumption and solar radiation on vertical surfaces are measured during specified time interval between sunrise and sunset. The results indicate that among the four proposed modules, the 18x18 module with a north-south orientation is the most optimal in the semi-arid climate of Tehran, and therefore, Type 3 layout demonstrates the best performance for energy consumption. This is while by incorporating selected nanotechnology (self-cleaning nanomaterial paint), energy usage decreases in all layouts, regardless of the season.