Abstract. The increasing population growth, heterogeneous distribution of water resources and periodical drought in the search for finding new sources of water is inevitable. Today, the use of treated wastewater is an important management option in the planning of water resources in many countries. Drip irrigation system is the best method for using treated wastewater. Emitters clogging are the most important drawback of the systems using treated wastewater. Clogging results in reducing the efficiency and distribution uniformity coefficient in drip irrigation. Therefore, a physical model of drip irrigation was designed and made for studying the effect of flushing frequency on the clogging reduction of Micro Flapper emitter and irrigation tapes. The mean discharge, discharge variations coefficient, and Christiansen's coefficient of distribution uniformity were used as indices for evaluating the clogging of the emitters. The results indicated that when using treated wastewater, the clogging of the emitters increased with time but their distribution uniformity reduced. Moreover, the research indicated that flushing at the end of irrigation season significantly causes increasing emitters’ discharge. In addition, it was found that monthly flushing results in the higher distribution uniformity coefficient and less discharge variations coefficient in Micro Flapper emitter and irrigation tape. The effect of flushing frequency and emitter type on the percentage of discharge reduction and discharge variations coefficient of the emitters was significant at one percent statistical level.