Cancer treatment in West Africa is shaped by a rich tapestry of traditional practices and modern approaches, reflecting both cultural heritage and contemporary medical advancements. This review explores the historical and current landscape of traditional cancer treatments in the region, emphasizing herbal remedies, spiritual practices, and the integration of traditional and modern medical approaches. Traditional cancer treatments often involve plant-based remedies such as African horned cucumber, baobab tree, and soursop, known for their antioxidant, anti-inflammatory, and potential anti-cancer properties. Spiritual and ritualistic practices, including prayer, energy healing, and sacred rituals, offer holistic support, addressing the psychological and emotional aspects of illness. The review examines the integration of traditional and modern practices, highlighting the potential benefits of a collaborative approach while addressing challenges such as safety, efficacy, and cultural sensitivity. Research efforts are focused on validating traditional treatments through scientific studies, standardizing remedies, and ensuring safety. Socioeconomic and cultural factors significantly influence treatment choices, with traditional medicine often serving as a more accessible and culturally resonant option for many patients. Case studies and community experiences provide valuable insights into the practical application of these treatments and underscore the importance of respecting cultural contexts. This review aims to provide a comprehensive understanding of traditional cancer treatments in West Africa, offering recommendations for future research and practice to enhance cancer care through an integrative and culturally sensitive approach. Keywords: Traditional Cancer Treatments, West Africa: Historical Practices.
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