Emergence Of New Knowledge Research Articles

Current technologies of response assessment in rectal cancer after neoadjuvant treatment: A review

Improvement of the multidisciplinary approach to the treatment of rectal cancer over recent years has led to the fact that in specialized high-volume oncology clinics it is possible to achieve a complete pathomorphological response to neoadjuvant therapy in a third of patients. The emergence of new knowledge about the development of tumor complete response and the accumulation of clinical experience opens up possibility for the wider use of an organ-sparing approach. Undoubtedly, making such a critical strategic decision requires reliable and effective tools for complete response predicting. This review is devoted to methods for assessing tumor response in patients diagnosed with rectal cancer. A look at the problem is presented from the perspective of modern methods of medical imaging, molecular and genetic studies, the study of the characteristics of the immune response, and a new look at clinical data. New data can form the basis for new patient selection algorithms for personalized treatment protocols for rectal cancer, thereby improving long-term results and quality of life for patients.

Implementation of a Pedagogical Model of Ocean Citizenship: Students’ Perspective

Abstract This article evaluates the implementation of the pedagogical model by Schio and Reis (2024), aimed at promoting ocean citizenship within basic education. The evaluation is based on a pilot project from the 2021/2022 school year, which involved 543 students, aged 10 to 11, from 10 Blue Schools located along the Portuguese coast. This paper reports on phases 3 and 4 of the Design-Based Research cycle, corresponding to the implementation and evaluation phases of the pedagogical model. Preliminary results allowed us to verify the emergence of new knowledge, skills, values, critical thinking and attitudes, reflecting the development of ocean citizenship competencies among students. These outcomes affirm the model’s applicability and its potential to seamlessly integrate ocean citizenship into the basic education curriculum. However, it was observed that the activism dimension requires additional emphasis. Further testing in diverse educational settings is crucial to refine the model, adjust to local nuances and maximise its impact on nurturing future generations committed to ocean sustainability.

Participatory design in telehealth research: Practical case examples.

Participatory design (PD) is a methodology that emphasizes user participation in the design of new technologies to leverage change within organizations and services. PD originated in the computer science field in the 1970s and 1980s when new programs and technologies were developed to empower workers, by involving them in decisions that affected them. PD in health research has been proven to change clinical practice. Genuine user involvement that includes all stakeholders, and robust collaborations across sciences, sectors, and disciplines are basic elements of successful research to change clinical practice and to implement novel technical and organizational approaches. This paper summarizes seven case studies involving the use of PD in telehealth research. All cases presented promoted organizational changes supported by health information and communications technology, and have been implemented at either international, national, regional, or local levels. We describe how PD can be applied in health sciences and used to facilitate organizational changes, new perspectives, and new communications methods. The relevance and suitability of PD as a research design in health science is explained, and recommendations for conducting PD studies in telehealth research are presented. In PD, mutual learning and co-creation is facilitated. Consequently, learning from users, rather than studying them, corroborates our understanding and the emergence of new knowledge.

Genetic and Digital Discrimination in Labor Law: Problem Statement

The last few decades have been characterized by the most active development of medicine and genetics, leading to the emergence of new knowledge about the functioning of the human body. The identification of a genetic predisposition to the development of certain diseases requires a rethink of traditional approaches to the use of employee personal data, labor protection, and the balance of public and private interests in labor legislation. This article analyzes approaches to determining the legal nature of genetic information, identifies possible areas of restriction of workers’ rights depending on the identification of hereditary predisposition to certain diseases, draws a line between discrimination based on genetic characteristics and differentiation. In the context of the active digitalization of personnel processes, the risks of possible digital discrimination in the selection and evaluation of employees using artificial intelligence technologies are noted.

Transforming International Marketing Education in the Digital Economy Era: A Paradigm Shift and Targeted Exploration

With the advent of the digital economy era, new technologies have given rise to new economies and business models. This has led to a shift in the economic landscape of business education services, transitioning from the industrial economy to the digital economy. Consequently, the field of business education requires innovation and transformation in its models and methods of instruction due to the emergence of new knowledge and skills. The new economy has brought about fresh objectives and demands for business education, necessitating active adaptation and reform in the teaching of international marketing courses to align with technological advancements and the development of the digital economy. This paper analyzes the background of international marketing course development in the context of the new era, emphasizing the need for a paradigm shift in education. It identifies existing shortcomings in current teaching processes and proposes targeted exploration plans for the reform of international marketing courses.

ВЛИЯНИЕ ПОНЯТИЯ «МЕДИА» НА СОЦИАЛЬНО-ЭКОНОМИЧЕСКУЮ И ПОЛИТИЧЕСКУЮ СФЕРЫ ОБЩЕСТВА В РАМКАХ ТОРОНТСКОЙ ШКОЛЫ КОММУНИКАЦИЙ

The article deals with the theoretical issues of the theory of communication. Information exchange between different systems is an object of communication. The subject field of the theory of communication can always be expanded with the emergence of new knowledge; there is an idea of a holistic, comprehensive development of the object under study with the involvement of data from different sciences. Synthesis of social, natural science and technical knowledge of a communicative nature in the context of the research of the Toronto School.

STRATEGI KOMUNIKASI UNTUK PENGEMBANGAN POTENSI WANITA MELALUI KOMUNITAS VIRTUAL (Studi Kasus Sharing Session Tema Wanita melalui Whatsapp Group Ciledug Female Community )

Nowadays, with the development of information and communication technology, all sectors of life are facilitated by the presence of the internet. . The use of social media as a new media that currently intersects with life and everyday life in all aspects of people's life also certainly has a very high impact on the emergence of new knowledge, both positive in nature or can also provide new experiences that have never been encountered in the real world and Various kinds of virtual communities emerge with various social goals in the group. The urgency of this research is to see the creation of a communication strategy for a virtual group of women through the WhatsApp application with the aim of providing maximum information and education to women, especially those who join the Ciledug Female Community.This research was conducted using a qualitative case study method with in-depth interview data collection techniques and non-participant observation. From the results of the analysis carried out, the Ciledug Female Community has carried out Sharing Session activities in the form of a good and planned communication strategy in accordance with the objectives that the community wants to produce, namely increasing knowledge and understanding of community members in various things that have never been obtained in space other virtual community spheres. The form of communication carried out in the Virtual Ciledug Female Community, especially at the Sharing Session, is sharing on social media, optimizing messages, managing conversations between resource persons and members and creating engagement between sources, committees and CFC members.Keywords: Communication Strategy, New Media, Virtual Community

Strategi Komunikasi Pemasaran Digital Melalui Sosial Media Klinik Sunat Modern Safubot Indonesia

The current development of communication technology has changed people's behavior in obtaining the variousinformation they want and of course also provided the emergence of new ideas and new innovations to simplify thecommunication process. The use of social media as one of the new media which is currently in contact with life anddaily life in all aspects of people's lives also of course has an impact on the emergence of new knowledge which isalso used as a marketing and promotional communication media in various business sectors, including CircumcisionHealth services. Modern Safubot Indonesia. The aim of this research is to determine marketing communicationstrategies through social media for health services, especially the Safubot Indonesia Circumcision Clinic. Theresearch method used in this research is a qualitative method with a case study approach. Safubot Indonesia'smarketing communication strategy planning uses social media using three events, namely, Sustain by alwayscontinuing to grow and develop by presenting information and communication that intersects with digital media.Second, Open New Market by expanding the branch which is a form of marketing communication which is alsocarried out through the Instagram branch. And the third is Open New Service with Safubot trying to open otherclinics with the main brand Safubot, such as business expansion in the field of other health services. Digitalmarketing communication activities are carried out using various social media such as websites, Instagram andYouTube, which include advertising content, sales promotions. , direct marketing as well as public relationsactivities

Professional Nurses’ Experiences Regarding Continuing Professional Development (CPD) Opportunities at Public Hospitals of Limpopo Province, South Africa

Rapid changes in health care, innovative technologies, and the emergence of new knowledge globally led to a need for enhancement in Continuing Professional Development (CPD) opportunities for nurses in public hospitals of Limpopo. However, they need to be empowered with updated knowledge and skills to adapt to these changes to enable them to render quality care to patients, resulting in fewer lawsuits. To explore and describe the experiences of professional nurses regarding CPD opportunities in the public hospitals of Limpopo Province. An exploratory-descriptive design was utilized in this study. Individual semi-structured interviews were used for data collection. Participants comprised 35 professional nurses who were purposely selected. Data collected were audio-recorded and transcribed verbatim. Data was analyzed using Tech’s eight-step data coding process, which led to the emergence of themes and sub-themes. Trustworthiness was ensured through credibility, confirmability, dependability, and transferability. Four themes emerged: Professional nurses’ understanding of CPD, Professional nurses’ views about necessary support needed for CPD, Professional nurses’ related to in-service training being offered, and Identified measures to resolve the challenges. Findings highlight that professional nurses value CPD and view it as important in learning new skills and improving standards of patient care and their self-esteem. Findings included challenges such as poor attendance of CPD activities and, lack of understanding of CPD, lack of access to CPD training, shortage of staff, and lack of funding and support by managers. Offering CPD opportunities regularly enhances knowledge and skills personally and professionally. However, more effective strategies are needed to address the identified challenges. Nurse Managers, Human Resources Departments, and the Department of Health need to be informed and updated on what is required in order to create and sustain effective and attainable CPD opportunities in the public hospitals of Limpopo Province.

A curated gene and biological system annotation of adverse outcome pathways related to human health

Adverse outcome pathways (AOPs) are emerging as a central framework in modern toxicology and other fields in biomedicine. They serve as an extension of pathway-based concepts by depicting biological mechanisms as causally linked sequences of key events (KEs) from a molecular initiating event (MIE) to an adverse outcome. AOPs guide the use and development of new approach methodologies (NAMs) aimed at reducing animal experimentation. While AOPs model the systemic mechanisms at various levels of biological organisation, toxicogenomics provides the means to study the molecular mechanisms of chemical exposures. Systematic integration of these two concepts would improve the application of AOP-based knowledge while also supporting the interpretation of complex omics data. Hence, we established this link through rigorous curation of molecular annotations for the KEs of human relevant AOPs. We further expanded and consolidated the annotations of the biological context of KEs. These curated annotations pave the way to embed AOPs in molecular data interpretation, facilitating the emergence of new knowledge in biomedicine.

Knowledge economy and economic culture in the formation of skills of transport industry staff

Methods. The theoretical and methodological basis of the research is the scientific works of domestic and foreign scientists on the problems of the knowledge economy and economic culture in the formation of skills of the personnel of the transport industry. The research methodology is based on the system approach, within which the following logical, general scientific, theoretical and empirical methods are applied: content analysis – to clarify a number of concepts that characterize the knowledge economy and economic culture in the formation of personnel skills; abstract-logical method – for theoretical generalizations and formulation of research conclusions. Results. Skill formation is necessary in order to reduce the time it usually takes for staff to gain experience in a new location, to quickly «blend» into the team, understand the demands placed on them, and quickly reach the required level of productivity. For a transport company, the skills formed significantly reduce staff turnover, which leads to a reduction in recruitment costs. The use of elements of economic culture as a system education includes professional knowledge, abilities, skills, special intellectual abilities and qualities, moral principles and value norms of personnel for providing transport services to the population. Novelty. Knowledge, qualifications, skills, abilities, competences, development, continuous training of personnel in the conditions of the knowledge economy are considered as integral components of the effective functioning and innovative development of the transport enterprise. The birth of new spheres of economic activity, the emergence of new knowledge and technologies, increased competition, changed the priorities of the development of most transport enterprises, putting people and their skills in the foreground as the main resource of economic growth. Practical value. The development directions of various tools for the effective formation of personnel skills have been formed, which allows to provide the transport enterprise with highly qualified and competitive personnel, able to quickly cope with the assigned tasks, demonstrate a sufficient level of professional competence and experience, become part of the team and find a common language with the direct manager. The importance of the knowledge economy and economic culture for solving tasks that affect the reduction of personnel management costs, the reduction of personnel turnover, and the improvement of the efficiency of its work are substantiated.

Interdisciplinarity in practice: Reflections from early-career researchers developing a risk-informed decision support environment for Tomorrow's cities

The concept of disaster risk is cross-disciplinary by nature and reducing disaster risk has become of interest for various disciplines. Yet, moving from a collection of multiple disciplinary perspectives to integrated interdisciplinary disaster risk approaches remains a fundamental challenge. This paper reflects on the experience of a group of early-career researchers spanning physical scientists, engineers and social scientists from different organisations across the global North and global South who came together to lead the refinement, operationalisation and testing of a risk-informed decision support environment for Tomorrow's Cities (TCDSE). Drawing on the notions of subjects and boundary objects, members of the group reflect on their individual and collective journey of transgressing disciplinary boundaries across three case studies between June–December 2021: operationalisation process of the TCDSE; development of a virtual urban testbed as a demonstration case for the implementation of the TCDSE; and consolidation of frequently asked questions about the TCDSE for communication purposes. The paper argues that (1) the production of boundary objects in interdisciplinary research nurtures relations of reciprocal recognition and the emergence of interdisciplinary subjects; (2) the intrinsic characteristics of boundary objects define the norms of engagement between disciplinary subjects and constrain the expression of interdisciplinary contradictions; and (3) affects and operations of power explain the contingent settlement of interdisciplinary disagreements and the emergence of new knowledge. Activating the interdisciplinary capacities of early-career researchers across disciplines and geographies is a fundamental step towards transforming siloed research practices to reduce disaster risk.

Proposals on Modifying Certain Provisions of GOST R 55194-12

Since the putting in force of GOST R 55194 Electrical Equipment and Installations for a.c. Voltages from 1 to 750 kV. General Methods of Dielectric Tests, 10 years have passed. The vast majority of the provisions of GOST R 55194 still remain relevant and do not require changes. At the same time, technical progress has led to the emergence of new knowledge about the physical nature of discharge phenomena and improvement of methods for digital processing of surge voltages. All this made it necessary to modify certain provisions of this regulatory document. The above refers to the procedure for determining corrections to test surge voltages of external insulation and digital processing of lightning voltage surges with superimposed high-frequency oscillations. As a result of the accomplished studies, new formulas filled with physical content have been proposed for determining the parameter q used to determine corrections for atmospheric conditions. Recently obtained new data on experimental studies of large-scale air insulation structures, insulation systems in SF6 and transformer oil have made it possible to propose a well-grounded expression for the test voltage function k(f), used for digital processing of lightning voltage surges with superimposed high-frequency oscillations.

Managing the Development of University Teachers’ Digital Pedagogical Competencies in Theory and in Practice

The article studies the development of higher educational institution teachers’ digital pedagogical competencies. Considering the current situation of uncertainty in higher education, the rapid change of digital platforms and services, the growing dynamics of changes and the emergence of new knowledge in the sphere of digital didactics, the authors propose a concept of forming a university digital transformation team. To meet the demand for high-quality digital educational products, there are required special organizational solutions, including the creation of pedagogical teams. The purpose of the article is to develop a model for assessing individual and team digital pedagogical competencies, which allows making managerial decisions and eliminating the lack of competencies in a team at the stage of designing digital educational products and services. The study analyzed the existing models of digital pedagogical competencies and drew the conclusion on the need to refine them with specific tools for assessing current individual and team digital pedagogical competencies for the development and implementation of an educational product or project. Based on the model proposed, the paper puts forward a general concept of a professional retraining program, which consists of three areas of assessment: technical, pedagogical, subject (area of research, direction of training). Based on the analysis of Ural Federal University’s experience of implementing distance learning using digital educational resources, the authors give recommendations on how to improve the efficiency of the development teams and the implementation of digital educational products. This publication might be of interest for managers of the higher education system, as well as for scholars and teachers interested in digitalization, digital didactics, digital transformation of universities and individualization of education.

Documenting Change from a Conversation Analytic Perspective: Introduction to the Spring Forum

Since its inception, Conversation Analysis (CA), which aims to describe the fine-grained machinery of talk (Sidnell, 2010), has uncovered an impressive range of “member’s methods”—how members of society accomplish social actions. The “lived work” of participants is, in fact, dynamic and complex: Facing new situations and unforeseen contingencies could inform how participants respond to similar situations in the future. And beyond tracing the emergence of new knowledge and practices, our understanding of member’s knowledge can also be extended by charting how novices of a community of practice develop competence and expand their repertoires. After all, novices do not become experts overnight; documenting the trajectories and evolutions of practices can provide important insights into the very process of becoming a competent member.

АНАЛІЗ ТРАНСФОРМАЦІЙ НАЦІОНАЛЬНИХ ЕКОНОМІЧНИХ ІНТЕРЕСІВ В УМОВАХ РОЗВИТКУ ІНФОРМАЦІЙНОЇ ЕКОНОМІКИ

The article is devoted to the analysis of transformations of national economic interests in the conditions of the development of the information economy. It was noted that the category "information economy" has a broader content than «digital economy». It has been proven that the trigger for the development of the information economy is: innovative digital technologies, information and the latest knowledge. Therefore, according to the author, the information economy is based on the digital economy and has a convergent relationship with the innovation and knowledge economy. The transformation of changes in national economic interests in the conditions of the transition from an industrial economy to an information economy is studied. It was noted that the key national interest in the period of the development of the industrial economy is centered around scientific and technological progress and material production, and in the period of the formation of the information economy - around the increase in data flows, the emergence of new knowledge, access to information technologies, which forms the latest vision of the development of society. Conflicts of national economic interests are outlined as a manifestation of unresolved problems in the development of the information economy. It is noted that the development of the information economy creates new economic, social and cultural value, the transformation of economic interests takes place within the framework of the level organization of the system of economic relations, and as a result, the newest model of society - the information society - is being formed. An analysis of the Western and Eastern models of the development of the information society was carried out, the results of which determined the confrontation between the West and the East in defending their national interests in the conditions of an irreversible and active process of information transformations and the formation of a new world map in the synergistic manifestation of the phenomena of the third, fourth and fifth industrial revolutions. An analysis of the practice of the Ukrainian model of information society development, which is at the initial stage of its formation, has been carried out.

Дитина в сенсорно-пізнавальному просторі: особливості використання технології Lego

The study has found that one of the means of effective learning in modern preschools are LEGO constructors, which have several positive characteristics, differ significantly from other constructors, primarily in terms of their features, functionality, modern technical and aesthetic characteristics and a possibility to use them in different games and for educational purposes. Theoretical analysis of research has shown the existence of a theoretical definition and identification of the characteristics of pedagogical technologies and published methodological approaches to the use of LEGO for the development of design activities of preschool children. Peculiarities of sensory perception of the environment by preschoolers in the conditions of marked design activity are substantiated. The pedagogical technology of children's development in a sensory-cognitive space is revealed, considering the principles of integrity, nature compliance, intensity, diagnostic purposefulness, reproducibility of LEGO constructor in the conditions of preschool education. Research and development work on the introduction of the pedagogical technology in the educational environment of the institution to form ideas about shape, colour, size, spatial orientation in children aged 4-6 years, and to develop their creativity. Potential possibilities of designing as especially important activity of preschool children are proved. It is established that the design process promotes the emergence of new knowledge in children from different spheres, improves the stock of knowledge and skills, stimulates imagination and creative initiative, develops general and fine motor skills, improves self-reasoning, helps discipline and order, has a positive impact on social climate in the group, promotes the development of individual independence, enriches social ties, develops self-esteem, self-confidence, promotes the development of speech, which contributes to success in school. Keywords: preschool children, LEGO constructor, design, pedagogical technology, sensory development, sensory-cognitive space, sensory standards, educational environment.

Connected Cities in Social Isolation: Impact of the Fourth Industrial Revolution facing Pandemic / Cidades Conectadas em Isolamento Social: Impacto da Quarta Revolução Industrial diante da Pandemia

The evolutionary process of the Fourth Industrial Revolution has faced the Coronavirus Pandemic and its challenges in combating the disease. Thus, this article aimed to reflect and indicate how disruptive technological advances allow society to readjust and adapt. In that regard, a revision was carried out which enabled an in-depth analysis of current references on the topic. It was observed that, even in times of social isolation, the community made important publications on the subject. It was also noted the emergence of new knowledge that brings new concepts and points out challenges to be faced and transformations to be carried out. These concepts can be used by public managers, urban planners, engineers and society as a whole to build smart and sustainable future cities.

Diversity, Complexity and Ordinality: Mental Health Services Outside the Institutions-Service Users' and Professionals' Experience-Based Practices and Knowledges, and New Public Management.

In conjunction with the dismantling of psychiatric hospitals, social workers have been commissioned to help service users in their daily living in their homes and in the community. The consequences of these changes for experience-based knowledge and practices in their contexts remain relatively unknown. In this study, eighteen service users and the social workers they described as helpful for them were interviewed. The interviews were recorded, transcribed, and analyzed using Thematic Analysis. The following themes emerged: “Here, there and everywhere”, “Doing, being, becoming”, “Talking” and “Order, planning and improvisation” concerning the contradictions service users and professionals mentioned about their practices and the conditions imposed by managerial methods connected to New Public Management. Finally, “Spontaneous planned complexity” was chosen as our overarching theme to characterize the new knowledge and practices which have been developed. The displacement of the place for the encounter and the introduction of non-medicalized professions have allowed community-based practices and thus the co-creation and emergence of new knowledge about the service users as persons and the professionals as qualified professionals. The challenge remains for managers to have trust in their colleagues and not impose rigid rules, schematized methods, and repeated controls.

Preliminary research in the development of smartphone-based e-module learning materials using the ethno-STEM approach in 21st century education

Education is the most important aspect in building knowledgeable and skilled human resources in the field of technology and 4C Skills known as the 21st century learning paradigm. In addition, education based on local culture related to scientific fields also needs to be considered as it is hoped that the emergence of new knowledge adapted from the local culture. Physics learning should lead students towards the desired learning goals and the role of teaching materials can also influence this. This study aims to obtain information related to the application of smartphone-based E-module using the Ethno-STEM approach. This research is a descriptive study conducted through direct observation at 3 schools with the research sample being students of class XI MIPA and 2 physics teachers in grade 11th and used an instruments in the form of questionnaire and interview sheets. The results of the data analysis show that the application of the Ethno-STEM approach has never been applied in learning. The need for teaching materials that support learning has to be up-to-date, namely smartphone-based E-Modules. Due to this, it is necessary to carry out further research in the form of the development of a smartphone-based Physics E-Module using the Ethno-STEM approach.