Stiffness-related geometric characteristics are closely linked to the performance of structural systems. The influence of foundation stiffness on the soil-structure interaction (SSI) mechanism was investigated by numerical modeling of different building foundations. Numerical tools (PLAXIS 3D and TQS/CAD) were used for decoupling analyses of the interaction between the structural components. Results obtained from instruments installed in a building case study were used to refine the numerical calculations. Linear elastic constitutive models and beam elements were useful in reducing computational processes and ensuring study feasibility. The simulation results provided a satisfactory representation of field observations. Interaction between piles and the environment governs the relationship between foundation stiffness and uniform settlement. Rigid pile groups are achieved with greater pile length, diameter and spacing. This study highlights the different effects of pile geometric parameters on loading and unloading rates in pillars, demonstrating that the SSI mechanism is more sensitive to less rigid foundations, particularly those with greater pile embedment. It was concluded that numerical simulations to predict settlement as realistically as possible require understanding and selecting the most appropriate model and type of calculation.