Elevated Index Values Research Articles

Foreign Migrants in the Moscow Agglomeration: Spatio-Temporal Analysis Based on Mobile Network Operator Data

Using mobile network operator data, the study analyzes the modern ethnic landscape of the Moscow agglomeration formed by foreign migrants. Their total number and monthly dynamics from October 2021 to October 2022 were analyzed. Foreigners’ main areas of residence were identified, the ethnic diversity of municipalities was assessed, and the main types of settlement pattern of national-ethnic communities were identified. The study showed that the total number of foreign migrants in the agglomeration reaches 1.8 mln people, or 9% of the total population, remaining almost unchanged against the backdrop of the events of 2022, including the special military operation. The share of foreigners is minimal in closed administrative-territorial units (below 3%), and it is also small in the remote parts of Moscow Region, as well as in expensive areas of the capital. At the same time, eight municipalities in the agglomeration have crossed the 17% mark, the so-called tipping point, reflecting a sharp increase in the risks of interethnic conflicts and ghettoization of the urban space. The two most noticeable areas of increased concentration of foreign migrants have been identified in the southeast at the junction of Moscow and Moscow oblast (Lublino–Kotelniki) and in New Moscow (Mosrentgen–Sosenskoe). Calculation of the Ekkel’ ethnic mosaic index has confirmed the presence of pronounced interethnic contact zones here. Elevated index values were also noted in most areas of the center and southwest of the capital, which, with a lower share of foreign residents, is associated with a high density of office buildings, diplomatic institutions, and universities. Analysis of the settlement patterns of national-ethnic groups of migrants revealed three types determined in accordance with the adaptive capabilities of ethnic communities. A diffuse, relatively uniform settlement pattern is characteristic of both the largest ethnic groups (citizens of Tajikistan, Uzbekistan, and Kyrgyzstan) and those most culturally close to the local population (immigrants from Ukraine and Belarus). A concentric settlement pattern (in residential areas of Moscow and satellite cities) is typical of relatively large ethnic groups from post-Soviet countries (citizens of Azerbaijan, Armenia, and Georgia). The local type is characteristic of small ethnic communities that gravitate towards certain areas of the capital.

Laryngopharyngeal Reflux Scoring in a Pediatric Population

In recent years, the prevalence of laryngopharyngeal reflux has risen, especially among pediatric patients. The diagnosis of laryngopharyngeal reflux relies on patient history and clinical assessment using the Reflux Finding Score and Reflux Symptom Index as crucial diagnostic tools. Some studies have proposed a link between pepsin and laryngopharyngeal reflux, potentially triggering palatine tonsil hypertrophy. Our study aimed to investigate the correlation between laryngeal and pharyngeal manifestations of laryngopharyngeal reflux through two questionnaires and the presence of pepsin in saliva and palatine tonsils in a pediatric population. Pepsin in saliva was detected using a Western blot method, while immunohistochemistry assessed its presence in palatine tonsils. Although no statistically significant differences in Reflux Finding Score and Reflux Symptom Index were found between the immunohistochemistry-positive (IHC-positive) and immunohistochemistry-negative (IHC-negative) groups, median reflux symptom index and Reflux Finding Score values consistently trended higher in the IHC-positive group. This suggests a potential connection between elevated index values and pepsin presence in tonsillar tissue. Further investigations are essential to fully comprehend the clinical implications of these findings.

Bannwarth's syndrome: serum and CSF IgG antibodies against Borrelia burgdorferi examined by ELISA.

A newly identified spirochete, Borrelia burgdorferi, has recently been established as the causal agent of chronic meningoradiculitis (Bannwarth's syndrome, BS). An etiological diagnosis can be obtained by specific antibody determination. To detect intrathecally produced Borrelia antibodies, we examined paired serum and CSF samples from 10 BS patients and 41 controls. CSF/serum IgG specific antibody indices were calculated by relating the CSF/serum ratio of specific antibody activity to the CSF/serum ratio of total IgG and of albumin; 8/10 BS patients compared to 4/39 controls had elevated index values. In only one of the 4 positive controls could spirochetal infection be excluded. We conclude that determination of specific antibody indices is a reliable and sensitive diagnostic test for nervous system B. burgdorferi infection.