Purpose: Labor intensity reduction and equalization accuracy improvement of cylinder powers of a multi-cylinder diesel locomotive on account of application as a diagnostic parameter, characterizing cylinder power unevenness, — the energy of low-frequency band of spectrum for crankshaft instantaneous angular velocity (CIAV) signal. Methods: Methods of mathematical modeling of diesel crankshaft instantaneous angular velocity, mathematical modeling of diesel engine working process, digital signal processing, spectral analysis, differential calculus and multidimensional non-differentiable function optimization are used in the work. Results: Method for equalization of cylinder powers of a multi-cylinder diesel locomotive that’s based on a continuous monitoring of the spectrum of crankshaft instantaneous angular velocity signal is proposed and justified. Energy of low-frequency band of the signal spectrum of CIAV can be used as a diagnostic parameter, characterizing cylinder load unevenness. The parameter value minimization by means of sequential correction of cyclic fuel supply and fuel advance angle ensures the decrease in the pointed unevenness. Practical importance: The proposed method can be used when adjusting fuel equipment after the repair of a diesel engine as with electronic fuel supply control systems as well as with hydromechanical fuel equipment. The use of the given method excludes the necessity of temperature measurement for exhaust gases and flash pressure measurement in cylinders for fuel equipment adjustment that’s especially important for high-speed diesel engines which cylinder heads’ construction doesn’t provide for indicator cocks. In the engines equipped with electronic fuel control systems, the use of IAV signal spectrum low-frequency band energy as a diagnostic parameter makes it possible to automate fully the equalization process for cylinder load. The result of the proposed method application will be the reduction in the duration and labor intensity of diesel locomotives rheostat tests as well as the rise in diesel locomotives reliability and efficiency at the expense of uniform loading of diesel cylinders.