The radio frequency circuit will generate strong electromagnetic interference in the process of signal transmission, and its own resistance to electromagnetic interference is weak, and the radio frequency circuits operating in the same electromagnetic environment are prone to mutual interference. Therefore, it is necessary to analyze the electromagnetic interference effect of radio frequency circuits, and then find effective suppression measures, build a good public electromagnetic environment, realize electromagnetic compatibility, and ensure the reliability of signal transmission. This research first briefly introduces electromagnetic interference and electromagnetic compatibility and then analyzes the key points of electromagnetic interference suppression in radio frequency circuits. On this basis, the specific application of electromagnetic interference suppression and electromagnetic compatibility technology of radio frequency circuit is discussed. It can serve as a guide for the design of the radio frequency circuit by analyzing the characteristics and suppression mechanism of the electromagnetic interference of the radio frequency circuit. To ensure the suppression impact of electromagnetic interference, various suppression measures are broadly implemented in accordance with the three components of electromagnetic interference. The electromagnetic compatibility-based design of RF circuits can reduce the mutual interference of RF circuits in the system and guarantee the stability and dependability of signal transmission.