The current industrial wireless sensor network (IWSN) cluster routing methods suffer from energy inefficiency. Designing efficient cluster-based routing protocols is crucial for improving network performance and energy efficiency. Therefore, this paper first designs a new clustering model to achieve efficient cluster head (CH) selection and data transmission performance by comprehensively considering multiple key factors such as CH energy, base station (BS) distance, packet loss rate, and data delay. Based on this clustering model, a novel cluster routing protocol based on Gaussian mutation adaptive artificial fish swarm algorithm (GAAFSA) is proposed. At the same time, a new Gaussian mutation strategy and an adaptive strategy were introduced to effectively promote the protocol to avoid local optima and prevent premature convergence. The GAAFSA based cluster routing protocol was experimentally compared with five popular schemes, namely CMSTR, D2CRP, EEHCHR, ESCVAD and BAFSA. The results showed that the proposed protocol outperformed the other four schemes in terms of network energy consumption, system lifetime, data transmission reliability, and latency. Specifically, GAAFSA has improved network lifespan by at least 15.68%, BS received packets by at least 7.46%, and reduced packet loss rate by at least 15.28%. Therefore, GAAFSA effectively optimizes network performance and extends network lifespan, greatly reducing energy loss within the network and significantly improving network quality of service (QoS).