Being the core of the ejector refrigeration system, an ejector with a suitable mixer, conical–cylindrical or cylindrical, is key to high-energy-efficiency and low-carbon systems. To promote the scientific selection of mixers for ejectors based on the theoretical models that have been validated by experiments, the evolution laws of the entrainment ratios in the two types of ejectors are studied under various operating conditions. Furthermore, the influence mechanism of the mixer structures on the entrainment ratio of the ejector is elucidated by comparing the distribution characteristics of the entropy generation rate, pressure lift proportion, and entropy generation rate of the per-unit pressure lift in the two types of ejectors. The efficiencies of the conical-cylindrical mixer ejector and cylindrical mixer ejector exist a crossover, which makes the entrainment ratio of the conical–cylindrical mixer ejector smaller under small compression ratios but larger under large compression ratios. By changing the cylindrical mixer into a conical one, on the one hand, more pressure rise will be distributed in the diffuser, which helps to reduce the entropy increase rate in the pressurization process; on the other hand, the wall impulse effect of the conical mixer will lead to an increase in entropy generation rate of per-unit pressure lift, resulting in a growing entropy generation rate of boosting. The dominant roles are not the same with changing compression ratios, which leads to different relationships of entrainment ratio between the cylindrical and conical mixer ejectors.