Research has documented a strong link between constructing episodic simulations-vivid imaginations of specific events-and empathy. To date, most studies have used episodic simulations of helping someone to facilitate affective empathy and promote helping intentions, but have not studied how episodic simulations of another's distressing situation affect empathy. Moreover, affective empathy encompasses both personal distress (i.e., an egocentric experience of distress in response to another's circumstances) and empathic concern (i.e., compassion for another), but we do not know how episodic simulations affect each component. To address these questions, we ran three experiments testing how different episodic simulations influenced personal distress and empathic concern, and thereby willingness to help. In Experiment 1 (N = 216), we found that participants who constructed episodic simulations of another's situation reported increased personal distress (but not empathic concern) and increased helping intentions compared to a control group; additional analyses revealed that personal distress mediated the simulation effect on helping. Furthermore, in Experiment 2 (N = 213), we contrasted episodic simulation of helping versus the distressing scenario; we found no differences in personal distress or helping intentions, but simulating helping led to higher empathic concern. Experiment 3 (N = 571) included both simulation conditions and a control condition; we fully replicated our findings, additionally showing that simulating a helping interaction increased personal distress, empathic concern, and helping intentions relative to the control condition, which consisted of prior work. Taken together, our work illustrates how distinct forms of episodic simulation differentially guide empathic responding and highlights the importance of personal distress in motivating helping. (PsycInfo Database Record (c) 2024 APA, all rights reserved).