Chromium metal is a potential toxin released by various industries as by products. Reduction of the same costs an ample amount of manpower and wealth. Alternate, economical, efficient, and sustainable form of chromium reduction while generating electricity is a boon that microbial fuel cell (MFC) has provided to man. It paves way for an attractive technique to process hazardous elements. Nature as well as the type of electrode modulates the efficiency of reduction and power production. Many previously published studies have reviewed chromium removal from effluents as well as through MFCs, but utilization of nanoparticle-based MFC for chromium removal has not been exclusively done before. Hence, the objective of the current review is to provide exclusive study on nanoparticle-assisted MFC for chromium reduction. Reputed published data from the past 5years have been studied meticulously to compare the best outcomes of MFC in chromium removal. Chromium is found to be removed mostly in double-chambered MFC with a maximum removal of 100% when iron is used as an electrode. Removal of the same has led to generation of maximum power of 1965.4 mW m-2 when palladium nanoparticles are used at the electrode. Removal rates of Cr(VI) from a mixture of NiCo2O4, MoS2, and graphite felt in a dual-chamber MFC showed an 8.13% increase after 24h of light exposure. Another efficient setup used MoS2 nanosheets and Alpha-FeOOH nanoparticles in a dual-chamber MFC to completely remove Cr(VI) and achieve a high removal ratio of 91.45%. The current study reviews the recent updates in chromium reduction through MFC and its significance in future as a potential instrument for bioremediation and energy source.