Efficient Glucose Detection Research Articles

Novel stylophora coral-like furan-based Ni/Co bimetallic metal organic framework for high-performance capacitive storage and non-enzymatic glucose electrochemical sensing

With the development of power supplies for wearable devices, electrode materials with dual functions have received extensive attention. Herein, we report a strategy of preparing stylophora coral-like Ni/Co bimetal metal organic framework (MOF) with furan-based derivatives as ligands through the simple solvothermal method, which can be utilized as a dual-function electrode material to build supercapacitors and non-enzymatic glucose sensing. It can be found that the high molecular stacking properties of the rigid furan ring skeleton combined with the unique stylophora coral-like morphology can greatly improve the charge transfer efficiency of the electrode reaction process, and the structure of the bimetallic node can effectively adjust the three-dimensional electronic structure, making high capacitive performance during charge storage. The specific capacitance of the furan-based bimetallic MOF material is as high as 531 C g−1 at a current density of 1 A g−1 with a high capacitance retention rate of 83.4% after 5000 cycles. In addition, the glucose sensing performance is analyzed and an outstanding sensitivity value of 366 µA mM−1 cm−2 is achieved with a low limit of detection (2 μM). The as-synthesized furan-based bimetallic MOF material is a promising candidate for electrochemical supercapacitors and efficient glucose detection.

Morphology control in oxygen-rich nanotubular titania for enzyme-free glucose detection

The necessity of research in food and nutrition and the emergence of diabetes mellitus call for fast and efficient glucose detection. Here, series of highly sensitive non-enzymatic photoelectrochemical glucose sensor based on engineered titanium dioxide nanotube arrays has been synthesized using a simple electrochemical approach to tune nanotubes morphology in a way that the highest sensitivity factor (525.5 µAmM−1cm−2) and saturation concentrations (0.18 mM) achieved in the photoelectrochemical sensor. The formation of oxygen-rich titanium oxide was confirmed by several techniques. Dependent on the growth condition, nanotube length changed from 1.9 to 8.4 µm while their inner diameter varied from 78 to 156 nm. According to the results, TiO2 nanotube arrays anodized for 4 h at 60 V presented the highest saturation concentration of 0.18 mM, which can be used for high glucose level demand cases. On the other hand, nanotubes anodized for 6 h at 50 V obtained the highest sensitivity factor of 525.5 µAmM−1cm−2 with an excellent detection limit and saturation level of 0.1 mM, which is beneficial for purposes involving slight changes in analyte amount. Both optimized sensors presented reasonable selectivity and stability providing optimum tubular TiO2 nanostructure morphology for developing non-enzymatic photoelectrochemical sensors.

Efficient glucose detection in anaerobic solutions using an enzyme-modified electrode designed to detect H2O2: implications for biomedical applications

The finding that a ‘first generation’ glucose oxidase modified poly(o-phenylenediamine) coated Pt electrode, designed to detect H2O2, responded to glucose in N2-saturated solutions with a sensitivity similar to that of air-saturated media is of cosiderable significance for the application of biosensors in biological systems where O2 availability is severely restricted.