Efficacy Of Ab Interno Trabeculectomy Research Articles

Long-term Effectiveness of Trabectome (Ab-interno Trabeculectomy) Surgery.

ABSTRACTAimTo evaluate the long-term safety and efficacy of ab-interno trabeculectomy with trabectome for the treatment of glaucoma.Materials and methodsData collected for 339 eyes which included demographics, intraocular pressure (IOP) measurements using Goldmann applanation tonometry, best-corrected visual acuity (BCVA), visual field results, optic nerve status, gonioscopic findings, prior glaucoma procedures, number of glaucoma medications and pain level. The main data points of interest were preoperative IOP vs. postoperative IOP and BCVA, medication use, pain status, and complications.ResultsOf the 339 eyes that underwent trabectome, we found a statistically significant reduction in IOP (p < 0.01) at final follow-up (average = 18.35 months) of nearly 23%, with a complication rate of 5.86%. Furthermore, this reduction was maintained up to 8 years post procedure. LogMAR visual acuity was significantly improved in 69% of eyes at the final visit (p < 0.05), while only 1.77% of cases saw a significant reduction. Based on these findings, we determined a success rate of around 80% to 100 months following trabectome.ConclusionTrabectome is a safe and effective long term for most forms and severities of glaucoma.How to cite this articleBendel RE, Patterson MT. Long-term Effectiveness of Trabectome (Ab-interno Trabeculectomy) Surgery. J Curr Glaucoma Pract 2018;12(3):119-124.

Evaluation of the long-term results of trabectome surgery.

The aim of this study was to investigate the safety and efficacy of ab interno trabeculectomy which is a minimally invasive glaucoma surgery, in the late period, performed via trabectome instrument. A total of 70 eyes followed up with a diagnosis of open-angle glaucoma (OAG) and undertaken trabectome surgery were included in the study. Preoperative and postoperative intraocular pressures (IOPs), number of the drugs used, and complications were retrospectively investigated and the data were evaluated. The criteria of success were accepted as an IOP value ≤21mmHg or ≥30% reduction in IOP and no need for a second operation. Mean IOP was decreased by 38% from a preoperative value of 28.77±5.34 to 17.62±2.81mmHg at the end of 18months. Likewise, mean drug usage was decreased by 48% from a preoperative value of 3.3±1.01 to 1.7±1.16 at the end of 18months. Both decreases were statistically significant (p<0.05). Postoperative success rates were 82.8% in the 6th month, 81.4% in the 9th month, 77.1% in the 12th month, and 70% in the 18th month. Most common complication observed was intraoperative reflux hemorrhage and no serious complication was observed. Trabectome surgery is an effective and safe method in early-stage open-angle glaucoma types that cannot be controlled despite maximal medical therapy. This procedure is a proper surgical option in patients targeted for moderate IOP without the need for a topical medication or with less drug usage.