AbstractFluid flow over rotating disk possesses many potential application in many engineering, biological, electrical, and chemical. Along with nanoparticles flow become more enriched in terms of chemical and physical properties. This study investigates the laminar, unsteady, incompressible flow of a water‐based nanofluid above a rotating, stretchable disk. The nanofluid consists of three distinct nanoparticles (magnetite), (copper), and (silver), under the influence of radiation. The behavior of the nanofluid is modeled using the Tiwari and Das model with generalized slip on the disk surface. The new facet of study is to examines the effects of different parameters including stretching, slip, radiation, skin friction, and Nusselt numbers on the flow dynamics. The fluid motion is driven by the rotation and stretching of the disk. Through appropriate similarity transformations, the governing partial differential equations for the flow and thermal transport processes are transformed into a set of coupled ordinary differential equations. These equations are then numerically solved using bvp4c method in MATLAB. The results indicate that velocities in both the radial and axial directions increase with rising stretching parameters, due which skin friction coefficient mount by . And, Nusselt number of fluid surge by increasing volume fraction of , , nanoparticles respectively. Additionally, the temperature increases with increment in the radiation parameter . An increase in the slip parameter's value results in a reduction in both radial and axial velocities.