Effects Of Vacuum Sealing Drainage Research Articles

Effects of Vacuum Sealing Drainage Combined with Ilizarov Bone Transport Technique in the Treatment of Tibial Traumatic Osteomyelitis.

BackgroundThe aim of this study was to analyze the efficacy of vacuum sealing drainage combined with Ilizarov bone transport technique in the treatment of tibial traumatic osteomyelitis and risk factors for postoperative pin infection.Material/MethodsWe enrolled 78 patients with tibial traumatic osteomyelitis admitted at the First People’s Hospital of Kashgar from January 2015 to September 2017 and treated with vacuum sealing drainage combined with Ilizarov bone transport technique.ResultsAfter combined treatment, SAS and SDS scores decreased significantly, while SF-36 scores increased significantly. Comparisons showed that there were significant differences in the scores of patients after treatment (P<0.05). Univariate analysis showed that there were no significant differences in gender, BMI, hypertension, diabetes mellitus, COPD, smoking index, alcohol abuse history, or residence (P>0.05). There were significant differences in age, fracture type, fixation type, pin loosening, and indwelling time between the 2 groups (P<0.05). Multivariate logistic analysis showed that age, fracture type, fixation type, pin loosening, and indwelling time were independent risk factors for pin infection. Age, fracture type, fixation type, pin loosening, and indwelling time are independent risk factors for pin infection in patients with tibial traumatic osteomyelitis.ConclusionsCombination of vacuum sealing drainage with Ilizarov bone transport technique can effectively improve the condition of tibial traumatic osteomyelitis, improve the quality of life of patients, and reduce the occurrence of adverse emotions of patients. Age, fracture type, fixation type, pin loosening, and indwelling time are independent risk factors for pin infection in patients with tibial traumatic osteomyelitis.

Effects of simple vacuum sealing drainage on the prevention and treatment of the subcutaneous effusion after breast cancer radical correlation

Objective To evaluate the curative effects of vacuum sealing drainage equipment on prevention and treatment of subcutaneous effusion after breast cancer radical correction. Methods A total of 122 cases of breast cancer patients from June 2006 to June 2012 were randomly divided into control group (n=62) and intervention group (n=60). The patients of control group underwent the conventional drainage while the patients of intervention group received the vacuum sealing drainage. The situation of subcutaneous effusion, infection, skin flap necrosis, decannulation time as well as day flow conditions in two groups were observed and compared. Results The incidence of subcutaneous effusion, infection and skin flap necrosis in control group were 12.9%, 6.4%, 8.1% respectively. In intervention group, the incidence rate of subcutaneous effusion was 1.7%, and no infection, and skin flap necrosis had been observed (χ2=7.90, 8.31, 9.12; P<0.01). The extubation time and day flow conditions in control group was(6.8±2.3)d and (70±38)ml, while the intervention group were (10.5±3.1)d and(105±28)ml with statistical significance (t=2.10, 3.95; P<0.05). Conclusions Simple vacuum sealing drainage device can not only prevent the subcutaneous effusion, infection and skin flap necrosis after breast cancer radical correction, but also can realize the early extubation, therefore it is worthy of promotion in clinical. Key words: Vacuum sealing drainage; Breast neoplasms; Subcutaneous effusion; Nursing

Vacuum sealing drainage combined with open bone grafting for treatment of chronic osteomyelitis

Objective To investigate the clinical effects of vacuum sealing drainage (VSD) combined with open bone grafting in treating chronic osteomyelitis.Methods The study enrolled 15 cases of chronic osteomyelitis treated by multiple debridement and VSD between February 2008 and November 2011.Whether necrotic wounds and abnormal effusion existed were identified and whether granulation tissues were fresh were determined.Open grafting with autologous iliac was performed provided that the wound infection was controlled and fresh granulation tissues appeared.Dressing change continued until fresh granulation began to grow on the surface of bone grafts and thin grafts were used to cover the wound after bone exposure disappeared.Results Mean period of follow-up was 22 months (range,14-58 months).Mean duration of therapy was 60 days (range,45-90 days).Mean period of VSD was 35 days (range,21-59 days).Controlled infection,diminished dead cavity,and healed wounds were achieved in 14 cases without relapse,but infection remained uncontrolled in 1 case.Conclusion VSD combined with open bone grafting is an effective method to control infection and facilitate growth of fresh granulation tissues and healing. Key words: Osteomyelitis; Bone transplantation; Negative-pressure wound therapy

Effects of vacuum sealing drainage on wound healing and plasma fibronectin

Objective To observe the changes in the levels of plasma fibronectin (Fn) before and after vacuum sealing drainage (VSD) in the treatment of wounds,and study the action mechanism of VSD.Methods The plasma samples were collected from 20 patients with soft tissue defect for determination of plasma Fn levels before and after the treatment with VSD.The growth of granulation tissue,the wound area and the wound healing were observed,and their correlation with plasma Fn level was analyzed.Results Before and after the treatment with VSD,the plasma Fn levels were (244.52 ± 27.02) and (277.69 ±28.34) mg/L (P ＜0.05),and wound granulation tissue score was (2.35 ± 0.89) and (4.73 ± 1.24)(P ＜ 0.05),respectively.The wound granulation tissue score was positively correlated with the plasma Fn level (r =0.883,P ＜ 0.05).The wound area after treatment [(165.58 ± 37.35) cm2] was significantly reduced as compared with that before treatment [(206.30 ± 43.40) em2,P ＜ 0.05],and negatively correlated with the plasma Fn level (r =-0.661,P ＜ 0.05).Conclusion VSD can increase the plasma Fn level,speed up wound granulation tissue growth,and promote wound healing. Key words: Vacuum sealing drainage; Fibronectin; Wound healing

Effects of vacuum sealing drainage on oxygen partial pressure and wound healing in rabbits

Objective To investigate the effect of vacuum sealing drainage (VSD) with different negative pressures on variation of oxygen partial pressure (PtO2 ) and wound healing in the rabbits.Methods Twelve rabbit wound models were made and randomly (random number) divided into two groups, namely vacuum group ( n =6 ) in which rabbits were treated with VSD by different negative pressures ( - 75 mmHg, - 125 mmHg, - 225 mmHg and - 350 mmHg) for 7 days, and routine treatment group ( n =6). At each interval of measurement, variation of PtO2 was measured by oxygen partial pressure admeasuring device, and area of VSD dressing and surface of wound were measured by vernier caliper, and growth of anaerobic bacteria was detected by bacterial culture, and morphological change and the course of wound healing were observed under by light microscope after HE tissue staining. Meanwhile anther two groups (n =6, in each) were set for comparing, including normal group, sham operation group. Results Average PtO2 value of vacuum group was in the range of ( 1.87 +0. 19) kPa to ( 1.54 ±0. 21 ) kPa which was decreased gradually in 7 days under different negative pressures. Average PtO2 value of routine treatment group and normal group were ( 2. 82 ± 0. 37 ) kPa and ( 5.79 + 0. 50 ) kPa, respectively which weresignificant higher than that in vacuum group ( P ＜ 0. 01 ). PtO2 was fell to 80. 94％ of its original value after VSD for 5 seconds, and continued the downward trend with the increasing of negative pressure at the same interval of measuring. Area of VSD dressing significantly decreased to 65. 36％ of its original area after VDS for5 minutes (P＜0.01). Surface of wound was minimized to 62. 82％ of its original area after VSD for 7 days ( P ＜ 0. 01 ), and variations of those in - 350 mmHg group were significant greater than those in other groups ( P ＜ 0. 01 ). There was no evidence of anaerobic bacteria growth in vacuum group during this experiment. Conclusions PtO2 could be down-regulated by VSD significantly without growth of anaerobic bacteria, and minimization of VSD dressing at - 350 mmHg was significantly helpful to reduce the area of wound for promoting the healing. Key words: Vacuum sealing drainage; Wound; Oxygen partial pressure; Anaerobic bacteria; Healing; Infection