Effect Of Bronchodilator Treatment Research Articles

EVALUATION OF TREATMENT BRONCHODILATORS AND CORTICOSTEROIDS IN COPD INPATIENT IN HOSPITALS DR. MOEWARDI SURAKARTA JANUARY 2016-JUNE 2017

Chronic Obstructive Pulmonary Disease (COPD) is one of the cause of mortality and morbidity in worldwide. This study aims to determine the pattern of treatment of bronchodilators with or without corticosteroids and their effects on changes carbon dioxide pressure in blood (PCO2) and oxygen pressure in blood (PO2) in COPD patients of inpatient in RSUD Dr. Moewardi Surakarta January 2016-June 2017. This research is a retrospective descriptive research design, data collecting by tracking medical records patients with 195 samples. The results showed that treatment of COPD patient using single bronchodilator of 30,8%, bronchodilator combination of 57,1%, bronchodilator combination with corticosteroid of 1% and corticosteroid equal to 91,3%.Effect of bronchodilator treatment without corticosteroids on changes in the largest largest PCO2 change of 14.8%, the smallest change in PCO25.9%, the largest PO2 change was 19%, the smallest PO2 change was 5.6%, whereas in patients who received bronchodilator treatment with corticosteroids there was the largest PCO2 change of 87.4%, the smallest PCO2 cha

Clinical effect of bronchodilator treatment on patients with chronic obstructive pulmonary disease

Objective To discuss clinical effect of bronchodilator treatment on patients with chronic obstructive pulmonary disease. Methods According to the exclusion criteria, 106 patients were selected and randomly divided into two groups, the control group were given glucocorticoid therapy, the study group was given glucocorticoid+bronchodilator treatment; lung index, including forced expiratory volume in one second, forced vital capacity, and the percentage of forced expiratory volume in one second of forced vital capacity of the two groups were compared, and the patient's clinical curative effect was observed. Results The patients of the study group of three indicators: forced expiratory volume in one second, forced vital capacity, forced expiratory volume in one second of forced vital capacity percentage were(1.6±0.8)L,(3.4±0.4)L,(48.6±2.3)%,which were higher than those of the control group, the differences were statistically significant(P<0.05); The total effective rate of the study group was 96.3%,which was higher than 81.2%of the control group,the difference was statistically significant(P<0.05). Conclusion The clinical effect of glucocorticoid+bronchodilator on patients with chronic obstructive pulmonary disease is good, which can effectively improve patient forced expiratory volume in one second, forced vital capacity, forced expiratory volume in one second percentage of forced vital capacity, and can avoid illness development, significantly improve the treatment efficiency. Key words: Chronic obstructive pulmonary disease; Bronchodilator; Clinical effect

Effects of bronchodilators on the behavior of pulmonary resistance and dynamic compliance as functions of respiratory frequency.

The effects of bronchodilator treatment (intravenous atropine or inhaled metaproterenol) on the behavior of pulmonary resistance (RL) and dynamic compliance (Cdyn) as functions of respiratory frequency were studied in patients with chronic obstructive pulmonary disease and in apparently normal smokers. No systematic changes in the frequency-dependent behavior of RL and Cdyn were observed after bronchodilator treatment; the degree of frequency dependence increased in some subjects, and decreased or remained unchanged in others. The present results suggest that the effects of bronchodilators on the relationships between lung mechanical properties and respiratory frequency are not based on a single mechanism, but probably reflect the interaction of multiple factors possibly associated with the bronchodilator treatment.