Background: the aim of the study is to evaluate the postoperative complications following tympanostomy tube insertion for children with otitis media with effusion and the effect of adenoidectomy on the complications. Methods: This is a case series study on 78 patients who underwent Shepard tympanostomy tube insertion, adenoidectomy was done for 52 of them. The operated cases for the period between March 2016 to March 2017 were included in the study, the patients were followed up postoperatively by a thorough otoscopic examination (by microscope or endoscope) at 1 week and at 1 month. Further control examinations were done once in every 3 months for further two years. Results: Seventy four children enrolled in the study, 43 were male and 31 were female, aged 3- 12 years. Early otorrhea occurred in (0.7%), late otorrhea occurred in (4.7%), granulation tissue was seen in (2.0%), early extrusion in (3.4%), plugged tubes in (0.7%), persistent perforation in (1.4%), myringosclerosis in (22.3%), atrophy in (0.7%). In three patients; two complications occurred in the same ear as follows: late otorrhea and myringosclerosis in the same ear in (1.4%), late otorrhea and persistent perforation in (0.7%), early otorrhea and atrophy in (0.7%). In our study medial displacement, retraction and cholesteatoma were not seen. Conclusions: Shepard tympanostomy tube insertion is an effective and safe procedure; nevertheless, it is associated with complications. Over all complications were less in patients who underwent tympanostomy tube insertion with adenoidectomy, especially late otorrhea.