Effectiveness Of Conservative Treatment Research Articles

Standards for providing emergency care at the prehospital and early hospital stages for patients with mechanical jaundice

Mechanical jaundice is a condition characterized by obstructive disorders in the biliary system, posing a diagnostic challenge that requires advanced visualization techniques and laboratory tests for accurate diagnosis. This article explores the role of biochemical markers, presents an analysis of the algorithm for laboratory diagnosis and visualization techniques in order to stratify patients with jaundice syndrome, and conduct timely and effective conservative treatment with further surgical interventions. A comprehensive diagnostic and therapeutic algorithm has been developed whose use by emergency physicians at the prehospital and early hospital stages will lead to a rapid and qualitative elimination of biliary obstruction, a reduction in the level of complications, and the achievement of optimal treatment outcomes for patients.

Daflon 500mg is used for the treatment of all grades of hemorrhoids

Background: Hemorrhoidal diseases are very common diseases found in surgical outpatient clinics, affecting populations all over the world. Treatments for the different grades of hemorrhoids include lifestyle changes, conservative medical therapy, and operative interventions. Objective: To assess the conservative treatment response of all grades of hemorrhoidal disease (grades 1-4) to a venotonic agent (Daflon 500mg). Patients and Methods: This is a prospective observational study of 196 patients with hemorrhoids, conducted during the period from January 2015 to January 2020, All treated with the standard dose of a venotonic agent (Daflon 500mg). An observation of the reduction and disappearance of the signs and symptoms of the different grades of the disease was done at 1, 3, and 6 months. Results: The mean age of the patients was 46.6 (range 14–85) years. The majority (41.84%) were diagnosed with grade III hemorrhoidal disease and 30.1% with grade II disease; Grade I and Grade IV constitute 9.69% and 18.37%, respectively. excellent improvement observed in about 72.45%, temporary response seen in 15.82% of cases. Conclusion: Daflon 500 mg is an effective first-line conservative treatment for all four grades of hemorrhoidal diseases, including grade 4, which has a 44.74% permanent response rate. This medical treatment, in turn, reduces the chance of surgical intervention and its complications.

The transdifferentiation of human dedifferentiated fat cells into fibroblasts: An in vitro experimental pilot study.

Skin grafting is a common method of treating damaged skin; however, surgical complications may arise in patients with poor health. Currently, no effective conservative treatment is available for extensive skin loss. Mature adipocytes, which constitute a substantial portion of adipose tissue, have recently emerged as a potential source of stemness. When de-lipidated, these cells exhibit fibroblast-like characteristics and the ability to redifferentiate, offering homogeneity and research utility as "dedifferentiated fat cells." We conducted an in vitro study to induce fibroblast-like traits in the adipose tissue by transdifferentiating mature adipocytes for skin regeneration. Human subcutaneous fat tissues were isolated and purified from mature adipocytes that underwent a transformation process over 14 days of cultivation. Microscopic analysis revealed lipid degradation over time, ultimately transforming cells into fibroblast-like forms. Flow cytometry was used to verify their characteristics, highlighting markers such as CD90 and CD105 (mesenchymal stem cell markers) and CD56 and CD106 (for detecting fibroblast characteristics). Administering dedifferentiated fat cells with transforming growth factor-β at the identified optimal differentiation concentration of 5 ng/mL for a span of 14 days led to heightened expression of alpha smooth muscle actin and fibronectin, as evidenced by RNA and protein analysis. Meanwhile, functional validation through cell sorting demonstrated limited fibroblast marker expression in both treated and untreated cells after transdifferentiation by transforming growth factor-β. Although challenges remain in achieving more effective transformation and definitive fibroblast differentiation, our trial could pave the way for a novel skin regeneration treatment strategy.

Analyze, design, develop, implement, and evaluate approach to develop a pelvic floor muscle training guidebook to treat stress urinary incontinence in women.

Stress urinary incontinence (SUI) is a common problem that affects the quality of life of women worldwide. Pelvic floor muscle training (PFMT) is an effective conservative first-line treatment for SUI. However, low compliance with PFMT is one of the main reasons for therapeutic failure. Indirect supervision using a guidebook may improve PFMT outcomes. To develop a PFMT guidebook using the analyze, design, development, implementation, and evaluation (ADDIE) method. A guidebook was developed from July 2020 to April 2021 using the ADDIE method. This prospective study used mixed methods, namely qualitative analysis, focus group discussions, and in-depth interviews, and involved various experts from urogynecology, urology, medical rehabilitation, and physiotherapy departments. A pilot study was conducted on patients with SUI to evaluate the effectiveness of the guidebook. The ADDIE method was successfully implemented to develop the PFMT guidebook. The formative evaluation of the ADDIE steps mainly focused on the PFMT technique, content clarity, illustration, design, and color choice of the book. After the pilot study, the guidebook significantly improved IIQ-7, 1-hour pad test, and perineometer scores. However, the pilot study showed no significant improvement in UDI-6 scores. The PFMT guidebook developed using the ADDIE method improved outcomes in patients with SUI.

The effectiveness of cervical rehabilitation interventions for pain in adults with myogenic temporomandibular disorders: A systematic review and meta-analysis.

Little evidence exists for the most effective conservative treatment approach for adults with myogenic temporomandibular disorders (MTMD). We aim to assess the effectiveness of cervical rehabilitation interventions on pain intensity and sensitivity in adults with MTMD compared to comparison intervention such as placebo, sham treatment, education or no intervention. For this systematic review and meta-analysis, we searched PubMed, EMBASE, Medline, PEDro databases, forward and backward citations and grey literature studies through PROSPERO, clinical trials and data registries without language or date restrictions between inception and 1 December 2021. We selected randomised controlled trials (RCTs) based on adult populations with MTMD who had a cervical rehabilitation intervention which was defined as any conservative intervention targeting the anatomical structures of the cervical spine. The primary outcome measures for pain were self-reported pain intensity and pain sensitivity through the pressure pain threshold (PPT) of the masseter and temporalis muscles. Secondary outcome measures of maximal mouth opening (on MMO) were included. Included studies were assessed for bias with the Cochrane risk of bias tool for randomised trials. Evidence from RCTs was synthesised to determine treatment effect size as differences between standardised mean difference (SMD) for changes in pain intensity, PPT and MMO comparing adults with MTMD who were treated with cervical rehabilitation interventions compared to a control group. This study is registered on Prospero, number CRD 42021289299. Our general search yielded 2647 studies where seven RCTs met eligibility criteria with low to some concerns in their risk of bias. Pain intensity (five studies, n = 223, SMD -0.98, 95% CI -1.67 to -0.28, I2 = 79%), PPT of the masseter muscle (six studies, n = 395, SMD 0.64, 95% CI 0.43 to 0.86, I2 = 90%) and the temporalis muscles (five studies, n = 295, SMD 0.76, 95% CI 0.07 to 1.45, I2 = 84%) showed large treatment effect estimates favouring cervical rehabilitation interventions compared to no treatment, sham cervical treatment, patient education or non-cervical neuromuscular techniques. Compared to control interventions, one type of cervical rehabilitation intervention, cervical manual therapy alone or in combination with a neck exercise program was associated with statistically significant, large treatment effect estimates on pain intensity (four studies, n = 203, SMD -1.52, 95% CI -2.50 to -0.55). This review found that in the short-term, cervical rehabilitation interventions especially upper cervical MT alone or in combination with a neck exercise program are effective in improving multiple pain outcomes in adults with MTMD. However, further research is needed to measure the long-term effects of this type of intervention.

Comparing the effectiveness of pulsed radiofrequency treatment to lumbar dorsal root ganglion according to application times in patients with lumbar radicular pain: protocol for a randomised controlled trial

IntroductionLumbar radicular pain (LRP) is a common symptom characterised by a sharp, shooting or lancinating sensation localised to one or more dermatomes of the lumbar spine. Despite its high prevalence...

Stress Urinary Incontinence in Young Female Athletes- From Prevalence to Treatment- A Review

Urinary incontinence is a prevalent issue among females aged 15-65, with prevalence rates ranging from 10% to 55%. Stress Urinary Incontinence (SUI) is the most common form in young athletes, with rates ranging from 0% (golf) to 80% (trampolinists). Activities like jumping, landing, and running can cause leakage due to an increase in intraabdominal pressure. This study aimed to identify management strategies and the prevalence of SUI in teenage female athletes. A literature search was conducted on studies conducted between 1990 and the present, excluding abstracted and non-open access studies. The research found that the chance of urinary stress incontinence in young and nulliparous female athletes in sports ranges from 0% (golf) to 80% (trampolinists). These activities, including gymnastics, long jumps, track and field, and ball activities, significantly impact their standard of existence, psychological situation, and athletic performance. Effective conservative treatment options for SUI include behavioral and lifestyle modifications, pelvic floor exercises, and core strengthening exercises. Female athletes require significantly stronger pelvic floor muscles than inactive females, and contraction of these muscles should occur as the inner core muscles are engaged. Future studies, instruction, and focused therapies are needed for female athletes with SUI.

New Infiltration Technique in the Treatment of the Plantar Fascia Syndrome Based on Platelet-Rich Plasma.

Pain in the attachment of the plantar fascia in the calcaneus represents 10% of all sports injuries, affects 10% of foot runners, and will affect around 20% of the world population. There is no effective conservative treatment for it. This paper justifies a new definition and name for this pathology, Plantar Fascia Syndrome (PFS), presents a methodology for its diagnosis, and presents the clinical and functional effectiveness of a new conservative treatment based on platelet-rich plasma (PRP). In total, 25 patients (from an initial sample of 260) diagnosed with recalcitrant PFS lasting for more than 12 months were treated with a single infiltration of 2 mL of PRP, according to a new technic proposed. The study was approved by the ethical committee for clinical research of the reference hospital. The patients were controlled after 15, 30, 90, and 180 days, reviewing on each occasion pain, thickness of the plantar fascia, and active extension of the ankle joint. A total of 15 days after infiltration, 85% of patients had no clinical signs requiring treatment. After 90 days of infiltration, no patients showed clinical signs. This improvement in the patients' condition lasted for 180 days. All patients after treatment can fully resume normal activity with no pain.

Supportive Care in Older Lymphoma Patients to Reduce Toxicity and Preserve Quality of Life.

The treatment paradigm in older patients with malignant hemopathies is the choice between an effective conservative treatment that preserves quality of life and an intensive, potentially curative treatment with more toxicities. For each patient, it is important to determine the risk/benefit ratio. The patient should be involved in the discussion, sufficiently informed and able to express himself and his expectations in terms of quality of life. However, this informed consent is conditioned by the ability of the patient to understand the risks and benefits of the treatment. Decline in quality of life is an important parameter for older patients with cancer and many prospective trials have now confirmed the impact of different side effects of treatment, such as recurrent hospitalization, loss of autonomy in daily activities, loss of contact with grandchildren and loss of cognitive functions. Interventions oriented to vulnerabilities detected in the older patients (by comprehensive geriatric assessment) and an optimal approach, including preventive measures to reduce treatment-related toxicity and mortality, are directly correlated to improvement in quality of life.

Conservative treatment of cholelithiasis: the effectiveness of the use of ursodeoxycholic acid

Relevance. Conservative treatment of cholelithiasis is most effective in the early stages of the disease. The use of ursodeoxycholic acid preparations is most justified, taking into account the pathogenesis of the disease. Effective conservative treatment can prevent the development of postcholecystectomy syndrome, the most common complication of surgical treatment. This is a socially significant task.Goal. Conducting conservative treatment with ursodeoxycholic acid to a patient with GI with dynamic monitoring and evaluation of the effectiveness of the therapy. Identification of early signs of the development of cholelithiasis and prevention of factors of the development of concretions in the gallbladder.Materials and methods. A patient with newly diagnosed cholelithiasis was prescribed ursodeoxycholic acid preparation under the control of laboratory and instrumental research methods. Dynamic observation of the patient was carried out during 1 year of treatment, and the previous results of ultrasound examination were also analyzed, which made it possible to identify predisposing factors of stone formation. The appointment of the drug ursodeoxycholic acid made it possible to achieve the goal – to «dissolve» gallstones. Regular ultrasound examination, even in the absence of clinical manifestations, is one of the methods for detecting cholelithiasis at an early stage – biliary sludge in the gallbladder.

The Effect of Karkatibeejadi Churna by Internal Administration in Mutraghata with special reference to Benign Prostatic Hyperplasia

Benign Prostatic Hyperplasia is a non-malignant enlargement of the prostate gland caused by excessive growth of prostatic tissue. The main symptoms of BPH include hesitancy, frequency, urgency, weak stream urination, straining and nocturia. These together termed as LUTS. We cannot see a single disease in Ayurveda which shows all the features of benign prostatic hyperplasia. Mutragranthi is one among the 12 types of Mutraghatas which can be compared with benign prostatic hyperplasia due to its similarities in morphological, anatomical, and clinical features. Lower urinary symptoms in patients are very troublesome which affects their daily routine and sleep pattern and a negative impact on their quality of life. Embarrassment and the treatment cost prevent them to take timely treatment. In modern system of medicines, the treatment of BPH is done by conservative and surgical therapies. These methods have significant complications and are too expensive. Karkatibeejadi churna is mentioned in Bhaishajyaratnavali in Mutraghata prakarana. The ingredients of this Choorna are easily available and easy to prepare and consume. This case study was done in a participant of age 67 years with symptoms of benign prostatic hyperplasia which was confirmed by USG in search of an effective, cost effective conservative treatment. The Choorna was given for 60 days and assessments were done on 0th, 16th 31st, 46th and 61st days and the result showed significant reduction in symptoms, prostate volume and post void residual urine of benign prostatic hyperplasia.

Pelvic Health Content in Canadian Entry-To-Practice Physiotherapy Programs: An Online Survey.

Pelvic health physiotherapy is an emerging and sensitive area of practice that offers effective conservative treatment for pelvic health conditions. Canadian entry-to-practice curriculum guidelines accord programs considerable flexibility regarding incorporating pelvic health content, which may lead to differences between programs and diverse levels of competence among new graduates. The purpose of this study was to determine the nature and extent to which pelvic health content is incorporated in entry-to-practice physiotherapy programs in Canada. We conducted a descriptive cross-sectional e-survey of representatives from Canadian entry-to-practice physiotherapy programs. Ten out of 15 Canadian programs participated. Programs incorporated pelvic health content throughout the required curriculum (n = 9) and in optional courses (n = 6). All participating programs covered musculoskeletal-related conditions, urinary incontinence, and pelvic pain conditions, and included anatomy and physiology, clinical reasoning, subjective assessment and pelvic floor muscle training topics. Three programs trained students in internal pelvic floor techniques in elective courses. All programs covered cisgender women populations, however, transgender populations were seldom covered. This study provides an understanding of pelvic health curricular content that can serve as a first step towards standardizing and improving entry-level pelvic health training in Canada.

A global assessment of forest integrity within Key Biodiversity Areas

Forest ecosystems cover one third of the terrestrial land surface, with those that are still functioning and largely intact being critically important for the conservation of threatened and endemic biodiversity. Key Biodiversity Areas (KBAs) are sites contributing significantly to the global persistence of biodiversity; >16,000 KBAs have been identified to date, almost half of which are of importance to forest species, including one-fifth that are important for one or more globally threatened species. It is important to track changes in forest integrity within KBAs to determine which important areas are under the greatest threat (so as to identify the actions needed), and also to track the overall effectiveness of conservation interventions. We utilised the Forest Landscape Integrity Index (FLII), which has been mapped globally at a 300 m resolution, to measure trends in forest integrity across 6844 KBAs of importance for forest biodiversity. In total 54 % (3.9 million km2) of these KBAs was forested, of which 44 % (1.7 million km2) is considered still to be of high integrity. South America, Africa and Asia were regions with the largest areas of high integrity forest within KBAs, while Oceania and Australasia had proportionally the highest amount of high forest integrity within their KBAs. We found that forest integrity was proportionally higher in larger KBAs, KBAs with larger proportions of forest, KBAs located close to other forested KBAs, and in protected KBAs. Unprotected and partially protected high-integrity forested KBA areas (making up 26 % of the current forested KBA estate) are among the highest priorities for assessing required conservation actions, including restoration to increase connectivity and reduce fragmentation and edge effects, and/or efforts to expand protected areas or other effective area-based conservation measures' (OECMs).

Quantifying population-level conservation impacts for a perpetual conservation program on private land

Area-based targets, such as percentages of regions protected, are popular metrics of success in the protection of nature. While easily quantified, these targets can be uninformative about the effectiveness of conservation interventions and should be complemented by program impact evaluations. However, most impact evaluations have examined the effect of protected areas on deforestation. Studies that have extended these evaluations to more dynamic systems or different outcomes are less common, largely due to data availability. In these cases, simulations might prove to be a valuable tool for gaining an understanding of the potential range of program effect sizes. Here, we employ simulations of wetland drainage to estimate the impact of the United States Fish and Wildlife Service Small Wetlands Acquisition Program (SWAP) across a ten-year period in terms of wetland area, and breeding waterfowl and brood abundance in the Prairie Pothole Region of North Dakota, South Dakota, and Montana. Using our simulation results, we estimate a plausible range of program impact for the SWAP as an avoided loss of between 0.00% and 0.02% of the carrying capacity for broods and breeding waterfowl from 2008–2017. Despite the low programmatic impact that these results suggest, the perpetual nature of SWAP governance provides promising potential for a higher cumulative conservation impact in the long term if future wetland drainage occurs.

Exploring the potential role of health resort medicine in the management of breast cancer-related lymphedema: a viable alternative for innovative rehabilitation opportunities?

Lymphedema is a chronic and progressive disorder of the lymphatic system that impairs the return of lymphatic fluid. Breast cancer treatment can cause breast cancer-related lymphedema (BCRL), with axillary lymph node dissection and regional lymph node radiation being established risk factors. BCRL can cause severe morbidity, disability, and reduced quality of life. Early detection and treatment are essential to prevent the disease from progressing and causing complications. According to the International Society of Lymphology, complex decongestive therapy (CDT) is the most effective conservative treatment for lymphedema. Aquatic exercise is a safe and effective form of therapeutic CDT exercise that can improve joint range of motion, reduce pain, and positively impact limb volume. Additionally, health resort medicine and thermal mineral-rich waters may provide synergistic benefits for therapeutic exercise programs. Therefore, we believe that consideration should be given to whether the spa setting could represent a viable alternative for the rehabilitation of BCRL patients.

Poster 177: Does Prior Ipsilateral Steroid Injection Affect Outcomes After Rotator Cuff Repair?

Objectives: Rotator cuff pathology is a common problem, affecting approximately 17 million individuals in the US. Among professional and competitive athletes, only 49.9% have returned to play at the same level as before their injury. Initial treatment often includes corticosteroid injections, but some patients continue to have pain resulting in surgical treatment. Although steroids are the mainstay of conservative treatment, recent studies have shown concerns for increased rates of postoperative infections and revision surgeries after RCR. This study aimed to determine the effect of prior ipsilateral steroid injection on outcomes following arthroscopic rotator cuff repair. Methods: A retrospective chart review was performed on 295 patients who underwent rotator cuff repair by a single fellowship-trained orthopedic surgeon from 2017-2019. Of the 225 patients that met inclusion criteria and underwent analysis, 42 patients were in the injection group (IG) and 183 in the control group (CG). Demographics, range of motion (ROM), patient-reported pain and satisfaction (0- 10), subjective shoulder value (SSV), complications and reoperations were compared between groups. Delta ROM and strength were defined as postoperative ROM minus preoperative ROM. Complications were defined as reoperations, retears, or subsequent infection. Statistical analysis included chi-square and student t-tests. Results: The cohort consisted of 57.4% males with an average age of 58.3, BMI of 29.5, and mean follow-up of 7.3 months. The mean time from injection to surgery was 5.6 months. There were no significant differences in demographics between the injection and control group. Preoperatively, the injection group had a significantly greater median supraspinatus strength (p=0.002), summed strength (p=0.003), forward elevation (p=0.003), abduction (p=0.005), and active external rotation (p<0.001). This was specific to injections received within the 12 months before surgery. Postoperatively, there were no significant differences between the groups on measures of pain, shoulder function, shoulder strength, range of motion, or SSV. The frequency of complications was also comparable between the no injection and injection group, having similar rates of persistent pain, limited ROM or stiffness, numbness or tingling, weakness, cervicalgia, adhesions, retear, and upper extremity DVT, and postoperative infections. Conclusions: The results of our study indicate that ipsilateral shoulder injection within one year of arthroscopic rotator cuff repair improves preoperative functional outcomes, namely improvements in forward flexion, abduction, external rotation, and relative strength. Despite enhancements preoperatively, postoperative measures of strength, range of motion, and complications are comparable between groups, which persists when analyzing the timing and number of injections. These results support the use of subacromial corticosteroid injections as an effective conservative treatment prior to rotator cuff repair. However, there is still a lack of consensus on how close in proximity to surgery it is safe to receive an injection and what preoperative patient characteristics may be more likely to benefit from injection prior to surgery. Future studies are needed to assess the short-term impact of corticosteroid injections on outcomes of rotator cuff repair, particularly in athletes.

Effects of customized insoles with medial wedges on lower extremity kinematics and ultrasonographic findings in plantar fasciitis persons

The customized insole is widely recommended as an effective intervention for pain reduction and foot function improvement in plantar fasciitis persons. However, it is unclear whether the additional correction of medial wedges could change the kinematics from the only insole. The objectives of this study were thus to compare customized insoles with and without medial wedges on lower extremity kinematics during gait and to determine the short-term effects of the customized insole with medial wedges on pain intensity, foot function, and ultrasonographic findings in plantar fasciitis persons. A within-subject, randomized, crossover design within motion analysis research laboratory was conducted among 35 persons with plantar fasciitis. Main outcome measures included joint motions of the lower extremity and multi-segment foot, pain intensity, foot function, and ultrasonographic findings. The customized insole with medial wedges produced less knee motion in the transverse plane and hallux motion in all planes during the propulsive phase than that without medial wedges (all p < 0.05). After the 3-month follow-up, the insoles with medial wedges decreased pain intensity and increased foot function. Abnormal ultrasonographic findings also decreased significantly after the 3-month treatment of insoles with medial wedges. Customized insoles with medial wedges seem superior to those without medial wedges on both multi-segment foot motion and knee motion during propulsion. Positive outcomes from this study supported the use of customized insoles with medial wedges as an effective conservative treatment in patients with plantar fasciitis.Trial registration: TCTR20210928006 (28/09/2021).

Aesthetic Conservative Management of Fluorosis Affected Teeth with Resin Infiltration: Case Report

Aims: The scientific case report aims to show recent technique of minimally invasive procedure for aesthetic resolution in moderate to severe fluorosis affected teeth.&#x0D; Presentation of Case: A clinical case of severe fluorosis was treated with microabrasion followed by resin infiltration. A commercial resin was applied on the facial surfaces of the anterior teeth resulting in masking of spots and re-establishing color uniformity.&#x0D; Discussion: The procedure proved to be a good option to mask spots associated with moderate to severe fluorosis. Moreover, it is a relatively quick, inexpensive and minimally invasive treatment.&#x0D; Conclusion: This case report demonstrates that the microabrasion and resin infiltration technique is an effective conservative aesthetic treatment. It minimizes an individual’s tooth discoloration when diagnosed with moderate to severe levels of dental fluorosis and has shown a good outcome even after twelve months.

Current Physical Therapy Management and Clinical Evaluation for Achilles Tendinopathy

Achilles tendinopathy (AT) is common in both the general population and athletes, especially in running and jumping sports. The incidence of AT is 43% in athletes, but as high as 83% in middle-distance runners. However, 30% of patients have a sedentary lifestyle. Currently, the physical therapy (PT) is an effective conservative treatment and more widely population. Objective this review article is update the most effective physiotherapy treatment and the most validity and reliability clinical evaluation for AT. Destination is to provide physical therapist guideline for select appropriate clinical practice. The results of the literature review found that key treatment recommendation for AT is to follow an eccentric exercise protocol, which is the most common intervention for the management of functional limitations in AT. Extracorporeal shockwave therapy (ESWT) is the most commonly used next step when patients do not respond to eccentric exercise. Also, eccentric exercise combined with ESWT and eccentricexercise combined with ankle joint mobilization can improve immediately enhance their quality of life more than either treatment alone. Clinical evaluation can utilize many tools but the VISA-A questionnaire was developed as a validity and reliability assessment for AT. A limitation of the VISA-A questionnaire is that it was designed for athletes only, and so is inappropriate for the general population. The FAOS questionnaire has been accepted as a valid and reliable tool for evaluating foot and ankle injuries. Clinical evaluation is recommended to choosethe appropriate assessment tool each patient (for the general population or athletes).

Utero-Vesical Fistula Closure after 3 Weeks Treatment with Intravenous Mesenchymal Stem Cells Infusion: Case Report

Objective: To describe the evolution of Utero-Vesical Fistula (UVF) of one patient who received conservative treatment using intravenous (IV) infusion of 120x106 Adipose tissue Mesenchymal Stem Cells (ADMSCs). Clinical case report: A 36-year-old female presented with postcesarean hematuria 3 hours after an emergency c-section was performed consequently to placental abruption during labor. The primary measure was to use a transurethral Silastic 18F Foley catheter to prevent bladder expansion. The catheter remained for 21 days. Evaluation through Computerized Tomography Cystography (Cysto-CT) revealed failure to close the fistula. The decision to inject ADMSCs as an IV single dose was done. Three weeks after this intervention no blood was seen in the urine drainage bag. Complete resolution of UVF was confirmed with a control CT urogram. Result: Total closure of UVF. Conclusions: The IV infusion of ADMSCs proved to be a plausible and effective conservative treatment of UVF.