This paper presents an adaptive path-tracking control of autonomous ground vehicles with sideslip effects and time-varying input delays. To handle the problem of unknown time-varying input delays, the vehicle kinematic model is transformed into a novel chain model, and a delay-based auxiliary integral term is introduced for the estimation of the unknown terms caused by time-varying delays. To avoid modeling errors caused by existing linear approximation methods, a new adaptive path-tracking control strategy is proposed, such that the optimal tracking performance is achieved by appropriately adjusting certain design parameters. In addition, the inherent complexity explosion issue is avoided with the aid of a boundary estimation strategy. All signals of the closed-loop systems are guaranteed to be bounded. Simulation results illustrate the effectiveness of the method proposed.