Abstract Oryzalin (3,5-dinitro N4, N4-dipropylsulfanilamide), oryzalin/chloramben (3-amino-2,5-dichlorobenzoic acid) combinations, and diphenamid (N,N-dimethyl-2,2-diphenylacetamide) were evaluated for their influence on root quality of sweet potato [Ipomoea batatas (L.) Lam.] at harvest and during storage. Mineral analysis and foliage dry matter were evaluated with no significant differences observed between the oryzalin rates, diphenamid, and the controls. Soluble carbohydrates, reducing carbohydrates, ascorbic acid, and carotene content were not influenced by the herbicidal treatments. Intercellular space values were all within an acceptable range at harvest storage. The 3 rates of oryzalin utilized were not detrimental to quality and comparable to the diphenamid, weedy control, and cultivated control treatments.