Effect Of Monensin Supplementation Research Articles

Effect of Monensin Supplementation in the Bovine Diet on the Composition and Anaerobic Digestion of Manure with and without Screening

Effect of Monensin Supplementation in the Bovine Diet on the Composition and Anaerobic Digestion of Manure with and without Screening

Effects of monensin supplementation on rumen fermentation, methane emissions, nitrogen balance, and metabolic responses of dairy cows: A systematic review and dose-response meta-analysis

To investigate the effects of supplemental monensin administration on the metabolic responses of dairy cows, a systematic review and dose-response meta-analysis were conducted. Initially, 604 studies were identified through comprehensive database searches, including Google Scholar, Scopus, Science Direct, and PubMed, using key words related to dairy cows, monensin, and metabolic outcomes. After a 2-stage screening process, 51 articles with a total of 60 experiments were selected for meta-analysis based on criteria such as study implementation date between 2001 and 2022, presence of a control group that did not receive monensin supplementation, reporting of at least 1 outcome variable, and presentation of means and corresponding errors. The meta-analysis used the 1-stage random-effects method, and sensitivity analyses were performed to assess the robustness of the results. The results showed that the administration of monensin at a dosage of 19 to 26 mg/kg was inversely related to methane emissions and that the administration of monensin at a dosage of 18 to 50 mg/kg resulted in a significant decrease in dry matter intake. Administration of monensin at doses of 13 to 28 and 15 to 24 mg/kg also resulted in a significant decrease in ruminal acetate proportion and an increase in propionate proportion, respectively, with no effects on ruminal butyrate, NH3, or pH levels. We found no effects on blood parameters or nitrogen retention, but a significant negative correlation was observed between monensin supplementation and fecal nitrogen excretion. Based on the analysis of all variables evaluated, the optimal dose range of monensin was estimated to be 19 to 24 mg/kg.

Effects of monensin supplementation on lactation performance of dairy cows: a systematic review and dose–response meta‑analysis

The aim of this study was to conduct a comprehensive review with meta-analysis to determine the effects of the dose–response relationship between monensin supplementation and dairy cow performance and milk composition. Results from 566 full-text articles and 48 articles with 52 studies were meta-analyzed for pooled estimates. Monensin supplementation up to 23 ppm increased milk production, with the optimal dose being 12.6 ppm. Monensin supplementation at doses ranging from 16 to 96 ppm increased milk production in the prepartum phase (− 28 to 0 day relative to calving). From 60 to 150 DIM, monensin supplementation up to 21 ppm had a significant positive effect on this outcome, while supplementation in the 37 to 96 ppm range caused a decrease in this variable. At 0 to 60 and > 150 DIM, monensin supplementation had no effect on milk yield. At dosages of 22 to 96 ppm, 12 to 36 ppm, and below 58 ppm and 35 ppm, respectively, monensin supplementation resulted in significant decreases in dry matter intake (DMI), milk protein percentage, milk fat percentage, and milk fat yield. Overall, based on the results of this meta-analysis and considering all variables, the recommended optimal dose of monensin could be about 16 ppm.

"Effect of Monensin Supplementation on Growth Performance of Crossbred Male Kids"

"Effect of Monensin Supplementation on Growth Performance of Crossbred Male Kids"

Effect of Monensin Supplementation on Serum Biochemical and Liver Specific Enzymes Activities in Early Lactating Buffalo (Bubalus Bubalus)

Effect of Monensin Supplementation on Serum Biochemical and Liver Specific Enzymes Activities in Early Lactating Buffalo (Bubalus Bubalus)

Effects of monensin supplementation and wheat pasture maturity on forage intake and digestion characteristics of cows grazing winter wheat pasture.

Effects of monensin supplementation and wheat pasture maturity on forage intake and digestion characteristics of cows grazing winter wheat pasture.

064 Effect of monensin supplementation on Brahman cow performance and postpartum follicular development

064 Effect of monensin supplementation on Brahman cow performance and postpartum follicular development

Effects of haylage and monensin supplementation on performance, carcass characteristics, and ruminal metabolism of feedlot cattle fed diets containing 60% dried distillers grains1

The objectives of this research were to determine the interaction of monensin and haylage supplementation for steers fed 60% dried distillers grains (DDGS) on 1) mineral status, performance, and carcass characteristics, and on 2) ruminal pH, H(2)S, and short-chain fatty acid concentrations. In Exp. 1, Angus-cross steers (n=168; BW=277 ± 67 kg) were blocked by BW and allotted in a 2 × 2 factorial arrangement of treatments to 24 pens. Dietary treatments were 1) 0 mg of monensin/kg of diet + 0% haylage, 2) 33 mg of monensin/kg of diet + 0% haylage, 3) 0 mg of monensin/kg of diet + 10% haylage, and 4) 33 mg of monensin/kg of diet + 10% haylage. The remainder of the diet was 60% DDGS, 10% corn silage, 15% supplement, and corn (either 5 or 15%) on a DM basis. When supplemented with 0 mg of monensin/kg of diet, added haylage increased ADG by 5.7%, whereas when supplemented with 33 mg of monensin/kg of diet, added haylage increased ADG by 13% (P < 0.01). No interactions of monensin and haylage were observed for DMI or G:F (P ≥ 0.36). Haylage inclusion increased (P < 0.01) DMI and decreased (P < 0.01) G:F. No interactions (P > 0.05) on plasma mineral concentrations were observed; however, over time, plasma Cu concentrations decreased (P < 0.01), whereas plasma ceruloplasmin and S concentrations increased (P < 0.01). There were no treatment effects (P ≥ 0.08) on carcass characteristics. Cattle fed the 60% DDGS diets benefitted from increased dietary forage, and the effects of monensin and forage were additive for ADG and final BW. In Exp. 2, ruminally fistulated steers (n=8; BW = 346 ± 34 kg) were used in a replicated 4 × 4 Latin square design and were randomly assigned to the diets used in Exp. 1. Haylage inclusion increased ruminal pH from 1.5 through 12 h postfeeding, and the effects of monensin supplementation were additive (P < 0.05). From 1.5 through 9 h postfeeding, steers fed 33 mg of monensin/kg of diet tended to have reduced (P ≤ 0.10) concentrations of H(2)S when compared with steers fed 0 mg of monensin/kg of diet. Acetate:propionate ratios at 6 h postfeeding were 0.94, 0.93, 1.29, and 1.35 for diets 1 to 4, respectively (P < 0.01); total lactate was decreased regardless of treatment (range: 0.94 to 1.42 µmol/mL). Sulfuric acid in DDGS, not ruminal short-chain fatty acids, may be responsible for the low rumen pH observed and may influence the maximum inclusion of DDGS in cattle diets. Monensin supplementation decreased H(2)S concentration and may decrease the risk of polioencephalomalacia for cattle fed high-DDGS diets.

Effects of Monensin on metabolic profile and feeding behavior of transition dairy cows (2011)

Thirty-two Holstein transition cows were used to determine the effects of monensin (Rumensin, Elanco Animal Health, Greenfield, IN; 400 mg/cow daily) on metabolism and feeding behavior. Cows were assigned randomly, based on calving date, to control or monensin treatments (n = 16 per treatment) 21 days before their expected calving date, and cows remained on treatments through 21 days in milk. Feeding behavior and water intake data were collected daily. Blood samples were collected at 8 different time points during the experimental period. Monensin decreased mean and peak plasma ketone concentrations, and also decreased time between meals before and after calving. No effects of monensin supplementation were observed on milk production or other metabolic traits. Furthermore, we observed no treatment effects on disease incidence, although sample size was small for detecting such effects.; Dairy Day, 2011, Kansas State University, Manhattan, KS, 2011; Dairy Research, 2011 is known as Dairy Day, 2011

Monensina para bezerros ruminantes em crescimento acelerado: 1. Desempenho

Os efeitos da suplementação de monensina no desempenho, nas características e na composição de carcaça, na coloração da carne e análise econômica parcial do experimento foram analisados após 120 dias de experimentação, utilizando 20 bezerros inteiros holandeses, com peso e idade médios, respectivamente, de 90,8 kg e 80 dias. Os tratamentos foram 0; 0,4; 0,8; e 1,2 mg de monensina/kg PV (peso vivo). Foram encontrados resultados com aumento dos níveis de monensina para ganho de peso (1,064; 1,312; 1,372; e 1,252), ingestão de matéria seca (4,158; 4,774; 5,028; e 4,752), ganho em perímetro torácico (32,60; 37,00; 39,80; e 36,60) e altura na cernelha (19,42; 23,64; 23,68; e 23,18), sendo os valores mais elevados obtidos com a dose de 0,8 mg de monensina/kg de PV. A conversão alimentar não diferiu entre tratamentos. As carcaças analisadas após o abate de todos os bezerrros, no término do experimento, também mostraram resultados vantajosos em rendimentos, com a aplicação da monensina, não apresentando alterações em sua composição. A avaliação econômica mostrou maiores benefícios com o uso do ionóforo, recomendando-se seu emprego no manejo alimentar de bezerros machos leiteiros.

The effect of monensin supplementation on ruminal ammonia accumulation in vivo and the numbers of amino acid-fermenting bacteria

When nonlactating Holstein cows (685 +/- 59 kg) were fed chopped timothy hay (9% CP, 7.0 kg/d) 12 times daily, the steady-state ruminal ammonia concentration was 2.6 mM, and the specific activity of ammonia production by mixed ruminal bacteria was 27.4 nmol/mg of protein-1.min-1. The addition of soybean meal (53% CP, 1 or 2 kg/d) to the basal diet caused a linear increase in ruminal ammonia (7.0 and 12.4 mM, respectively; P < .001), but there was only a small increase in the specific activity of ammonia production (30.7 and 33.8 nmol/mg of protein-1.min-1, respectively; P < .05). The addition of monensin (350 mg/d) to the diets caused more than a 30% decrease (P < .01) in ruminal ammonia at all levels of soybean supplementation, and there was a similar decrease (P < .001) in the specific activity of ammonia production. Before monensin addition, the most probable number of bacteria that could utilize peptides and amino acids, but not carbohydrates, as an energy source for growth was 5.8 to 7.0 x 10(6)/mL. When monensin was added to the diets, these bacteria decreased (P < .001) nearly 10-fold. Based on these results, it seemed that monensin inhibited highly active amino acid-fermenting ruminal bacteria, and this inhibition, in turn, decreased ruminal amino acid deamination and ammonia production. Because monensin did not increase soluble protein, peptides, or amino acids in ruminal fluid, it did not seem that the decrease in ammonia increased flow of dietary amino N to the lower gut.(ABSTRACT TRUNCATED AT 250 WORDS)

Effect of monensin on total volatile fatty acid production by steers fed a high grain diet.

Four rumen-fistulated steers, averaging 315 kg during two experimental periods were used in a replicated 2 X 2 Latin square study designed to determine the effects of monensin supplementation on rumen volatile fatty acid (VFA) production, pH and liquid volume. A 72% steam-flaked, sorghum grain diet was fed twice daily at 0700 and 1700 h at 2.0% of live body weight. Production rates were determined at 11 times during a 24-h feeding cycle by short-term in vitro incubations of whole rumen contents. Monensin increased moles/100 mol (P less than .05) and production rate (mumoles X liter-1 X min-1; P greater than .01) of propionate and depressed moles/100 mol (P less than .01) and production rate (P less than .05) of butyrate. Moles of acetate/100 mol were not affected (P greater than .05) by monensin. Daily propionate production (moles) was increased (P less than .01) by 37% by monensin. Monensin increased total production of acetate (11%) and total VFA production (16%), both nonsignificantly. Both rumen pH and liquid volumes were increased nonsignificantly by monensin.

A note on the effect of monensin supplementation on growth and food utilization in young calves

ABSTRACTThe effect of monensin supplementation on suckling male dairy calves was studied on a commercial farm. Twenty-eight calves were given monensin supplements from the age of 1 week and compared with a similar group not given monensin. During a 52-day suckling period, the supplemented calves gained 0·12 faster, with little difference in the conversion ratio of metabolizable energy into live weight. During the subsequent 42 days, there was no difference in daily gain, but the supplemented animals were 0·064 more efficient in the conversion of metabolizable energy into live weight.

Effect of monensin supplementation on growth, feed digestibility and utilization in young calves

ABSTRACTTwo feeding trials were carried out with Israeli Friesian male calves, commencing at an average age of 7 to 10 days, and covering a suckling period of 30 days followed by a further 90 days. A conventional starter, or one that contained cotton hulls, was used. In each experiment one group of 10 animals served as a control and a similar group was monensin-supplemented. No coccidia were found in the animals. In experiments 1 and 2 monensin supplementation was associated with increased daily gains of 10% and 47% during the suckling period and of 6% and 17% during the next 90 days, but only the differences obtained in experiment 2 were significant. In both experiments, dry-matter intake relative to body weight was higher with monensin supplementation in period 1, but reduced in period 2. The effect of monensin on molar proportions of acetic and propionic acids was smaller than that reported by previous authors for older cattle.A separate digestibility trial showed that monensin administered to suckling calves, either with milk replacer or directly into the rumen, improved dry-matter digestibility, increased the excretion of amylase, and tended to reduce that of trypsin and chymotrypsin.