Effect Of Chlorhexidine Mouthwash Research Articles

EFFECT OF 0.2% CHLORHEXIDINE GLUCONATE ON GINGIVAL HEALTH AMONG ORTHODONTIC PATIENTS- A RANDOMIZED CLINICAL TRIAL

Objectives: The objective of this study was to compare the eff ect of chlorhexidine mouthwash on gingival health in orthodontic patients using manual brushing as a control in terms of reduction in gingival and bleeding indices scores.Methods and materials: This randomized clinical trial was conducted on August 2021 to December 2021 at Department of Orthodontics, Bacha Khan Dental College, and Hospital Mardan. A sample size of 50 orthodontic patients divided into two groups. Group A (experimental) and enrolled 25 participant ,and Group B (control) enrolled 25 participants used non-probability convenient sampling technique. Group A used chlorhexidine mouth wash along with manual brushing while in group B the participants maintained oral hygiene with manual brushing only. Patient’s age between 12 to 35 years, undergoing fi xed orthodontic treatment, with no anterior composite restorations and no decalcifi cation of teeth were included. At baseline and after period of one month the gingival and bleeding indices were recorded. Comparison of mean gingival and bleeding indices score was done between both groups using Paired T test. P≤0.05 was considered significant.Results: The mean gingival index score was less in cases using Chlorhexidine (1.77±0.75) than control group (2.19±0.52) statistically signifi cantly (P=0.026, 95% CI =0.053, 0.786). Similar results were found for bleeding index (P=0.034, 95% CI =0.027, 0.670). The females (n=29, 58%) were more than males (n=21, 42%). The mean age was 19.94±4.48 years with range from 13 to 34 years. The comparison of age (P=0.066), baseline gingival index (P=0.397) and bleeding index (0.377) were not diff erent statistically.Conclusion: Chlorhexidine mouth wash additional to the daily oral hygiene regimen can reduce gingivitis in orthodontic patients.

Evaluation effect of chlorhexidine and green tea mouthwash on saliva pH and plaque index

Aims: Applying mouthwash has an important role in reducing caries when compared to other prevention methods. The purpose of this study is to compare saliva pH and plaque index before and after using chlorhexidine mouthwash and a mouthwash with green tea extract. Materials and Methods: Forty dental students were randomly assigned to two groups (chlorhexidine and green tea mouthwash). A week before research getting started and during that, the students were asked to use normal diet and Bass brushing method. Salivary pH and plaque index of the participants were measured before, 1 week, and also 2 weeks after the use of mouth washes. Then, the data were analyzed based on Friedman, Mann–Whitney, and repeated-measures ANOVA tests. Results: The mean pH was significantly different in the three times of 1 week prior, during, and 2 week after the treatment for the green tea group (P = 0.01). However, there was no significant difference in the chlorhexidine group (P = 0.211). The mean of new plaque in both chlorhexidine green tea groups was significant (P < 0.001). The mean of plaque formation at <48 h in chlorhexidine and in green tea was both significant (P < 0.001). Conclusion: The effect of chlorhexidine mouthwash and green tea on salivary pH and plaque index was the same in a week. However, the effect of green tea was more than that of chlorhexidine in a 3-week application.

The effect of chlorhexidine mouthwash on bacterial microcolonies in recurrent tonsillitis

The effect of chlorhexidine mouthwash on bacterial microcolonies in recurrent tonsillitis

Short-Term Impact of Two Kinds of Vegetables to Exogenous Total Nitrate and Nitrite Intake: Is Antibacterial Mouthwash Influential?

Background:Nitrate is a compound with adverse effects on human health that can exist also in vegetables. This study aimed to determine the intake of total nitrate/nitrite from lettuce and carrot as high and low nitrate content, respectively. Moreover, the effect of chlorhexidine mouthwash on the elimination of the nitrite level in saliva and urine was surveyed.Methods:This study was designed as a crossover based on the randomized selection method. Thirty-nine participants were divided into two groups; the lettuce and carrot juice consumers (control group). The case group was consumed these two vegetables, while they used antibacterial mouthwash. The background of nitrate/nitrite of the participants was determined before exposure. The intake of total nitrate and nitrite via lettuce and carrot juice consumption was investigated. The Griess colorimetric reaction was used for nitrate and nitrite determination in samples.Results:Total nitrate concentrations in case and control groups were detected 0.79 and 0.78 mM in saliva and 1.78 and 1.38 mM in urine after lettuce consumption, respectively. However, it was determined 1.55 and 2.43 mM in saliva and 2.92 and 3.04 mM in urine after carrot ingestion. Salivary nitrite concentration 0.53 mM was decreased to 0.45 mM after antibacterial mouthwash application (P-value <0.05).Conclusions:This study indicated that the intake of total nitrate/nitrite via leafy vegetables was higher than rooty ones. The chlorhexidine mouthwash is an appropriate recommendation to reduce the nitrite concentration in the human body for preventing the probable side effects of nitrate metabolites such as N-nitrosamines forming.

Comparison of the effects of chlorhexidine mouthwash with jaftex in periodontal index

Comparison of the effects of chlorhexidine mouthwash with jaftex in periodontal index

Comparison of the Antibacterial Effects of Chlorhexidine Mouth Washes with Jaftex Mouth Wash on Some Common Oral Microorganisms : An in Vitro Study

Comparison of the Antibacterial Effects of Chlorhexidine Mouth Washes with Jaftex Mouth Wash on Some Common Oral Microorganisms : An in Vitro Study

Clinical and Microbiological Effects of Chlorhexidine Mouth Wash, Chlorhexidine, Metronidazole and Combination Gel on Patients Undergoing Fixed Orthodontic Treatment-A Comparative Study

Clinical and Microbiological Effects of Chlorhexidine Mouth Wash, Chlorhexidine, Metronidazole and Combination Gel on Patients Undergoing Fixed Orthodontic Treatment-A Comparative Study

Genotoxic Effects of Chlorhexidine Mouthwash on Buccal Epithelial Cells

Objective: To study the genotoxic effect of Chlorhexidine mouthwash on buccal epithelial cells in chronic gingivitis patients. Methods: Chronic gingivitis patients(n=50) who were exclusively on mechanical plaque measures were taken as Controls(Group A) and chronic gingivitis patients who were on mechanical plaque measures along with adjunct 0.2 % Chlorhexidine mouthwash (n=50) were taken as Cases (Group B). Buccal epithelial cells were taken from these patients and were collected in a buffer and the centrifuged at 8000 rpm for 5 minutes. The cells were fixed with cold methanol (100%). The slides were kept at 37°C overnight and then stained with 5% Giemsa stain. The micronuclei frequency was calculated by observing 2000 nucleated cells per individual slides under microscope. Results: The average micronuclie frequency in Cases (4.62 ± 0.433) was approximately eight folds greater as compared to the Controls (0.6 ± 0.125). However, the total number of micronucleated cells that were present in Cases and Controls were 140 and 28 respectively. This study was statistically significant with p<0.01. Conclusion: Our findings with the micronucleus test indicate that the use of anti plaque agent chlorhexidine induces DNA damage resulting in genotoxicity.

A prospective clinical evaluation of the longevity of resorbable sutures in oral surgical procedures

The objectives of this prospective randomized study were to clinically evaluate the longevity of resorbable sutures (chromic catgut and vicryl) and determine the effect of chlorhexidine mouth wash on their absorption time in oral surgical procedures. Both sutures were of size 3/0 with round body needle and were placed using the standard technique. One hundred patients selected for the study were divided into two groups of 50 patients each (vicryl and chromic catgut groups). Each group was subsequently subdivided into chlorhexidine (17 cases); warm saline mouth wash (17 cases) and warm water mouth wash (16 cases (control). The sutures were placed during various minor surgical procedures e.g. third molar surgery (65 cases), incisional biopsy (7 cases), excisional biopsy (8 cases), sutured lacerations (10 cases) and malar elevations through intraoral upper buccal sulci approach (8 cases) and 2 cases of cystic enucleations. The mean longevity of chromic catgut for chlorhexidine was 11.4 days with a range of 5-16 days. The patients, who used warm saline mouth wash, had a mean longevity of 11.7 days with a range of 7-24 days. The mean longevity of vicryl in patients that used chlorhexidine was 22.7 days, with a range of 14-36 days and that of warm saline mouth wash was 24.5 days with a range of 14-47 days. The resorbable sutures investigated have a mean longevity, which was slightly shorter than the figure stated by the manufacturer. Chlorhexidine was found to have no appreciable effect on absorption time of the sutures.

Effect of chlorhexidine mouth wash and fluoridated mouth wash on mechanical properties of orthodontic arch wires (An in vitro study)

Effect of chlorhexidine mouth wash and fluoridated mouth wash on mechanical properties of orthodontic arch wires (An in vitro study)

P145 Effect of chlorhexidine mouth-wash on presence of Lactobacillus spp. in saliva of patients with chronic periodontitis

P145 Effect of chlorhexidine mouth-wash on presence of Lactobacillus spp. in saliva of patients with chronic periodontitis

Clinical effects of chlorhexidine mouth washes on patients undergoing orthodontic treatment

clinical effects of chlorhexidine mouth washes on patients undergoing orthodontic treatment

Clinical effect of chlorhexidine mouthwashes on patients undergoing orthodontic treatment

Background: This study compared the short-term clinical effect of 0.12% chlorhexidine digluconate as an adjunct to regular oral hygiene practices. Material and method: This study done on 26 adolescent (ages 11 to 15 years) undergoing orthodontic treatment. Thirteen subjects were experimental (CHX) and other 13 were control (C) groups. Baselines values were recorded 10 days after prophylaxis which include plaque index PL.I, gingival index G.I gingival fluid flow (G.F.F.) and discoloration index (D.I). Both groups (CHX and C) received soft tooth brushes with instruction to brush twice daily as well as CHX mouth rise twice daily with 15ml for 60 seconds for experimental groups .Reevaluation were performed 1, 2, 3 months after baseline except for the D.I which was only assessed at 3 months. Result: no difference between groups was seen at baseline for any of the parameters. The changes of PL.I, G.I. G.F.F. at 1, 2, 3 month were statistically significant in the case of experimental groups, as the changes in the months. The D.I shows high scores in the experimental group as compared to control group but they were not statistically significant. Conclusion: The data shows that the use of CHX in addition to regular oral hygiene habits was effective in reducing plaque and gingivitis in adolescent undergoing orthodontic treatment.

A 4-month study on the effect of chlorhexidine mouth washes on 50 soldiers.

abstract – Aqueous solutions of chlorhexidine salts have been used as mouth washes to supplement routine oral hygiene in a group of young adults for a period of 4 months. In the first part of the study (2 months) the effect of plaque formation and gingival condition in the presence of calculus and rough surfaces was studied. Under such circumstances the chlorhexidine mouth washes reduced the amount of plaque on an average of 66%, whereas the gingival inflammation was reduced by 24% in the same period. In the next 2 months the effect of chlorhexidine was studied on scaled and polished teeth. The plaque reduction was now 84% and the Gingival Index values were reduced by 43% after subgingival scaling. No effect on gingival inflammation adjacent to pockets exceeding 3 mm was observed.

Side effects of chlorhexidine mouth washes.

abstract – The side effects of chlorhexidine mouth washes have been evaluated in a group of 50 soldiers during a period of 4 months. Previous publications have shown the effects on plaque formation and gingival conditions. The present paper discusses unfavorable side effects. When rinsing with 0.2 and 0.1 % chlorhexidine gluconate and acetate, some desquamations and soreness in the oral mucosa were observed. Twelve per cent of the tooth surfaces and 62 % of the silicate fillings were discolored, while 36 % of the test persons developed discolored tongues in the experimental period. Because of the side effects, there. are some objections to uncritical use of chlorhexidine in preventive dentistry. A close control is necessary; and until more information is gained, the use of chlorhexidine mouth washes is recommended for short periods only. Other methods of application must be studied.