Effects Of Aerial Parts Research Articles

Effect of Aerial part and Root Extracts from Ferulago mughlae Pe?men and Ferulago sandrasica Pe?men Quézel Growing in Turkey on Erectile Dysfunction in Streptozotocin-Induced Diabetic Rats

Effect of Aerial part and Root Extracts from Ferulago mughlae Pe?men and Ferulago sandrasica Pe?men Quézel Growing in Turkey on Erectile Dysfunction in Streptozotocin-Induced Diabetic Rats

Effect of aerial part and root extracts from Ferula orientalis L. growing in Turkey on erectile dysfunction in streptozotocin-ınduced diabetic rats

Effect of aerial part and root extracts from Ferula orientalis L. growing in Turkey on erectile dysfunction in streptozotocin-ınduced diabetic rats

Effect of Aerial Parts and Root Extracts from Four Ferulago Species on Erectile Dysfunction in Streptozotocin-Induced Diabetic Rats

Effect of Aerial Parts and Root Extracts from Four Ferulago Species on Erectile Dysfunction in Streptozotocin-Induced Diabetic Rats

Therapeutic effects of aerial parts of Smyrnium cordifolium ethanolic extract on ethylene glycol-induced kidney calculi in rats

Introduction: In this study, the effects of the ethanolic extract of aerial parts (stem and leaves) of Smyrnium cordifolium (S. cordifolium) Boiss on the ethylene glycol(EG)-induced kidney calculi in rats was investigated. Materials and methods: Thirty-six male Wistar albino rats were randomly divided in 6 groups. Group I (normal control), Groups II (control of EG) to VI received EG 1% v/v in water for 28 days. Animals in Groups III and IV (preventive groups) received ethanolic extract of stem and leaves of S. cordifolium in 200 mg/kg and 400 mg/kg orally in water for 28 days, respectively. Groups V and VI (treatment groups) received extract in 200 mg/kg and 400 mg/kg orally in water from 15th to 28th day, respectively. Results: Results showed that the level of urine oxalate, blood urea and creatinine in EG group vs. normal control significantly increased (P<0.001). Extract did not show significant effect on urinary oxalate, urine volume and other blood biochemical parameters in the treatment groups (V and VI). Provision of extract resulted in significantly lower levels of urine oxalate and higher level of volume, serum creatinine and blood urea in III and IV groups as compared with Group II (P<0.05). Conclusion: These observations enable us to conclude that the ethanolic extract of aerial parts of S. cordifolium Boiss is effective against EG induced urinary calculi in rats.

Anti-Inflammatory and Anti-Allergic Effects of Adenophora triphylla var. japonica Extract

Asthma is an increasing global health problem, and novel strategies to prevent or ameliorate the condition are needed. The purpose of the present study was to evaluate the anti-inflammatory and anti-asthma effects of Adenophora triphylla var. japonica extracts. We investigated the molecular mechanism underlying the effects of 80% ethanol extracts (AE) of A. triphylla on lipopolysaccharide (LPS)-stimulated RAW 264.7 cells. AE treatment inhibited pro-inflammatory cytokines such as TNF-α and IL-6 as well as nitric oxide (NO) production in LPS-stimulated RAW 264.7 cells. In particular, NO and pro-inflammatory cytokine production was suppressed more effectively by aerial parts (AE-A) than roots (AE-R) of A. triphylla. Quantitative RTPCR assay showed that AE reduced mRNA levels of iNOS and COX-2. We also evaluated the anti-asthmatic effects of AE-A in an ovalbumin (OVA)-induced BALB/c mouse model. AE-A supplementation significantly reduced the amounts of airway eosinophils, IL-4 and IL-13 levels in BALF, and IgE levels in serum as compared with untreated, OVA-induced mice. These results suggest that AE-A can be considered as a therapeutic agent to potentially relieve asthma.

Evaluation of analgesic and Anti-inflammatory effects of aerial parts of Breynia rhamnoides Muell. Arg

The plant Breynia rhamnoides Muell. Arg (family-Phyllanthaceae/Euphorbiaceae) was reported to have numerous potent constituents and the same plant was used for many traditional medicines. Phytochemical analysis of ethanolic extracts of Breynia rhamnoides revealed the presence of many active compounds such as flavonoids, glycosides, phenolic compounds, terpenoids, steroids and saponins. Present work describes the extraction and evaluation of analgesic and anti-inflammatory activities of aerial part extract of Breynia rhamnoides . Acute toxicity studies were performed as per OECD-423 guidelines. Toxicity signs and symptoms were not observed. Anti-inflammatory activity was evaluated by carrageenan-induced paw edema model and analgesic activity by Eddys hot plate method and Acetic acid induced writhing method in Wistar albino rats. The extract exhibited significant anti- inflammatory and peripheral analgesic activity.