Effects Of Acute Coronary Occlusion Research Articles

Changes in the slope of the first major deflection of the ECG complex during acute coronary occlusion

To evaluate the effect of acute coronary occlusion (ACO) during percutaneous coronary intervention (PCI) on the slope of the first major deflection of the QRS complex (the initial QRS slope). Standard ECG signals of 18 patients (89 leads), undergoing PCI were recorded prior to and during ACO. The initial QRS slope was calculated in the baseline state and during ACO. Changes in the standard ECG were detected in 36 of 89 leads (40%). The initial QRS slope during ACO was significantly different from baseline in 74 of 89 leads (83%). The specificity of the change in the slope during ACO was low (29%).

Functional Effects of Acute Coronary Occlusion and Catecholinergic Stimuli on the Isolated Normothermic Hemoperfused Porcine Heart

The aim of this study was to characterize functional parameters in the isolated and normothermic hemoperfused porcine beating heart model after pathophysiological stimuli for extended perfusion periods. Hearts were prepared and connected to a specially developed perfusion equipment, which simultaneously allowed perfusion with warm autologous blood as well as blood dialysis. Two groups were established: group A (12 hearts: no intervention) and group B (6 hearts: occlusion of the ramus circumflexus of the left coronary artery for 2 hours). Blood gas analyses and oxymetry were performed at baseline and every 30 min during a 6 hours perfusion period. Coronary perfusion pressure (CPP) and blood flow (CBF), right and left ventricular pressure, blood and dialyzate pH‐values, and temperature were monitored online by a microcontroller. A steady state regarding the CPP and the CBF was achieved after 1 hour of perfusion for both groups. In group B, CPP increased during occlusion. Comparison of both groups showed no significant differences in the bicarbonate and sodium levels in blood and dialyzate. The potassium concentration in blood and dialyzate increased in both groups constantly during the experiments. No clear alteration of the oxygen consumption was observed. Lactate levels in blood and dialyzate increased during occlusion as did the aspartataminotransferase (AST) venous levels (both determined only for group B). Four concentrations of norepinephrine were injected into the stem of the coronary arteries (10, 20, 40, 80 µg). A clear inotropic effect of this hormone on right and left ventricular pressure was observed. It was concluded that longer perfusion periods and simulation of myocardial infarction for a clinically relevant period can be performed using this model. In addition, right and left ventricular function appear to be well preserved in this model, since the isolated porcine heart responded to norepinephrine stimuli.

The effects of acute coronary occlusion on noninvasive echocardiographically derived systolic and diastolic myocardial strain rates

Purpose To compare the magnitude and rates of change of peak systolic (ϵ ′ SYS) and diastolic (ϵ ′ DIAS) strain rates, as measured using tissue Doppler echocardiography, to pressure and volumes left-ventricular indices during acute coronary occlusion. Methods Six closed-chest dogs had a combination high-fidelity conductance pressure transducer placed into the left ventricle for determination of end-diastolic and end-systolic pressures (EDP and ESP) and volumes (EDV, ESV, and ejection fraction [EF]). Other indices included the time constant of left-ventricular relaxation (τ), +dP/dt max, −dP/dt max, end-systolic pressure/volume index (ESPV). A coronary angioplasty catheter was positioned into the left-anterior descending coronary artery. During coronary occlusion, strain rates and hemodynamic parameters were recorded continuously for 2 minutes. Results During occlusion, significant decreases in strain rates occurred within 30 seconds. Systolic indices (ESPV and +dP/dt max) changed at rates similar to ϵ ′ SYS (each p = NS). Diastolic indices (τ, EDP, EDV, −dp/dt max) also changed at rates similar to ϵ ′ DIAS (each p = NS). However, EF decreased at a significantly slower rate than did strain rates (p < 0.05). CONCLUSIONS: Peak systolic and diastolic strain rates decrease with acute ischemia similar to corresponding indices of left-ventricular systolic and diastolic function. Strain rates may be used in the noninvasive assessment of ischemic-induced left-ventricular dysfunction.

Effect of Acute Coronary Occlusion on the Size of the Dynamically Perfused Coronary Capillary Bed in the Dog

The aim of the present study was to investigate the influence of reduced left anterior descending (LAD) coronary arterial blood flow on the size of the perfused coronary capillary surface area (CCSA) in dogs. The transcoronary hydrolysis (v) of the specific ACE substrate, [3H]benzoyl-Phe-Ala-Pro, was estimated and the parameterAmax/Km(proportional to the size of the perfused CCSA) was calculated. By means of a ligature placed around the LAD, LAD blood flow was transiently reduced to 36.0 ± 4.1 (E1) and 17.4 ± 4.3% (E2) of control; in a separate maneuver the first diagonal branch of the LAD was ligated to achieve 40.0 ± 6.7% (E3) of control flow. Thevvalues remained unchanged at around 0.7 forE1,E2, andE3determinations, suggesting unaltered substrate transit time through the coronary capillary bed.Amax/Kmvalues decreased to 36 ± 5, 17 ± 4, and 47 ± 10% of control forE1,E2, andE3determinations, respectively, reflecting a flow-proportional decrease in CCSA. Values of the transpulmonary measures ofvandAmax/Kmperformed at the beginning and end of the protocol were unchanged. These results support the hypothesis that reduction in coronary blood flow will produce proportional decreases in the size of the CCSA. This new procedure can thus serve as a useful tool for investigating alterations in the size of the CCSA in different species and under various pathophysiologic challenges.

Effects of acute coronary occlusion and previous ischaemic injury on left ventricular wall motion in humans.

OBJECTIVE: To assess the acute effects of single and repeated coronary artery occlusions, during percutaneous transluminal coronary angioplasty (PTCA), on left ventricular long axis function in patients with stable and...

Coronary Artery Collateral Visualization During Acute Coronary Occlusion

Filling of a severely stenosed or totally occluded coronary artery by collateral vessels is often seen during coronary angiography. Of central importance is the rate of development and physiologic significance of collateral vessels during acute coronary occlusion. Percutaneous transluminal coronary angioplasty (PTCA) provides a convenient model to study effects of acute coronary occlusion. 1,2 In this study we used balloon occlusion to evaluate the time course of development of coronary collaterals after acute coronary occlusion and the relation of angiographically demonstrable collateral filling to manifestations of ischemia.

Effects of acute coronary occlusion on hemodynamics in an adjacent coronary artery in dogs

The effects of acute occlusion of 1 coronary artery on flow responses in another were studied in 24 open-chest dogs. Left circumflex (LC) flow was measured with and without LC stenoses before and during reactive hyperemia. In 19 dogs the left anterior descending artery (LAD) was occluded and measurements were repeated after 1 hour (group 1). Four dogs had measurements before and after 1 hour without LAD occlusion (group 2). In group 2 no systemic, left ventricular (LV) or coronary hemodynamic changes were observed after 1 hour. In group 1, an hour after LAD occlusion, heart rate and aortic pressure had not changed but stroke volume decreased slightly (-8 +/- 7%, mean +/- SD, p = not significant) and LV end-diastolic pressure had increased (2 +/- 3 mm Hg, p less than 0.05). Basal LC flow was not changed by less than 90% LC stenosis. Ninety percent LC stenosis decreased LC flow both before and after LAD occlusion. During reactive hyperemia without LC stenosis, LC flow decreased after LAD occlusion in 15 of 19 dogs (from 154 +/- 80 to 141 +/- 75 ml/min, p less than 0.05). With 60 and 80% LC stenoses, LC flow during reactive hyperemia decreased before LAD occlusion (110 +/- 62 and 74 +/- 40 ml/min, respectively), but decreased further (both p less than 0.05) after LAD occlusion (98 +/- 54 and 63 +/- 43 ml/min).(ABSTRACT TRUNCATED AT 250 WORDS)

Comparison of effects of acute coronary occlusion in acutely and chronically denervated canine hearts

Comparison of effects of acute coronary occlusion in acutely and chronically denervated canine hearts

Effects of acute coronary occlusion on the motion and perfusion of the normal and ischemic interventricular septum.

To establish the effect of local and remote myocardial ischemia on interventricular septal motion, 27 open-chest dogs were studied using ultrasound and radioactive microspheres. In 14 dogs the left anterior descending coronary artery was ligated. If the ultrasound beam traversed ischemic septum (proximal LAD occlusion), significant (P less than 0.05) declines in systolic septal velocity (26.4 +/- 2.9 to 6.4 +/- 1.8 mm/sec), and excursion (2.6 +/- 0.3 to 0.7 +/- 0.2 mm) occurred, and systolic thickening was reduced. Similar significant changes were seen when the ultrasound beam traversed nonischemic septum adjacent to the ischemic area (distal LAD occlusion). In 13 additional dogs, circumflex coronary ligation produced posterior ischemia. The mean septal velocity for this group increased significantly (21.8 +/- 2.6 to 26.5 +/- 3.3 mm/sec), as did the septal excursion (2.5 +/- 0.2 to 3.1 +/- 0.4 mm). We conclude that acute LAD occlusion causes a reduction in systolic velocity, excursion, and thickening of both the involved ischemic and the adjacent nonischemic septum. When myocardial ischemia was produced in a part of the ventricle remote from the septum, septal velocity and excursion increased.

Effect of acute coronary occlusion on myocardial nutritional circulation in swine

Page 1069: B. B. Howe and M. M. Winbury, "Effect of acute coronary occlusion on myocardial nutritional circulation in swine." Page 1071: figures 2 and 3 should be reversed.

Effect of acute coronary occlusion on myocardial nutritional circulation in swine.

ARTICLESEffect of acute coronary occlusion on myocardial nutritional circulation in swineBB Howe, and MM WinburyBB Howe, and MM WinburyPublished Online:01 May 1969https://doi.org/10.1152/ajplegacy.1969.216.5.1069This article has been correctedMoreSectionsPDF (1 MB)Download PDF ToolsExport citationAdd to favoritesGet permissionsTrack citations ShareShare onFacebookTwitterLinkedInWeChat Previous Back to Top Next Download PDF FiguresReferencesRelatedInformation Related ArticlesEffect of acute coronary occlusion on myocardial nutritional circulation in swine 01 Dec 1969American Journal of Physiology-Legacy ContentCited ByIn vivo relation of intramyocardial blood volume to myocardial perfusion. Evidence supporting microvascular site for autoregulation.Circulation, Vol. 85, No. 2Effects of acute coronary occlusion on hemodynamics in an adjacent coronary artery in dogsThe American Journal of Cardiology, Vol. 54, No. 8Regional coronary venous flow responses to transient coronary artery occlusion in human beingsJournal of the American College of Cardiology, Vol. 2, No. 1Coronary hemodynamics during percutaneous transluminal coronary angioplastyThe American Journal of Cardiology, Vol. 49, No. 7BLOOD FLOW AND RELATIVE TISSUE OXYGENATION OF NORMAL AND PARTIALLY ISCHAEMIC MYOCARDIUM: EFFECT OF CO 2Clinical and Experimental Pharmacology and Physiology, Vol. 5, No. 6Prolonged epicardial mapping of myocardial infarction: The effects of propranolol and intra-aortic balloon pumping following coronary artery occlusionThe Journal of Thoracic and Cardiovascular Surgery, Vol. 72, No. 6Distribution of myocardial blood flow in the exercising dog with restricted coronary artery inflow.Circulation Research, Vol. 38, No. 2Intracoronary nitroglycerin, pentaerythritol trinitrate and dipyridamole on intramyocardial oxygen tensionMicrovascular Research, Vol. 4, No. 3 More from this issue > Volume 216Issue 5May 1969Pages 1069-1074 Copyright & PermissionsCopyright © 1969 by American Physiological Societyhttps://doi.org/10.1152/ajplegacy.1969.216.5.1069PubMed5768054History Published online 1 May 1969 Published in print 1 May 1969 Metrics

Immediate hemodynamic effects of acute coronary occlusion and their modification by anesthesia

Biplane cineangiography was used to study the effects of an acute reversible circumflex artery occlusion by an implanted exteriorized polyethylene snare in the intact anesthetized dog. Occlusion of the left circumflex coronary artery produced an increase in end-diastolic (43 to 58 ml.) and end-systolic volumes (19 to 37 ml.) in 12 studies. Ejection fraction fell (57 to 36 per cent), whereas stroke volume was often unaltered. A regional loss of contractility in the myocardium supplied by the occluded artery was observed cineangiographically as was late systolic mitral insufficiency, probably as a result of papillary muscle dysfunction.Because different anesthetics produced different control states, the influence of two anesthetics on the hemodynamic response to occlusion were compared. The circumflex artery occlusion with chloralose-urethane anesthesia resulted in a fall in heart rate (149 to 131/min.) and mean blood pressure (134 to 98 mm. Hg) and a rise in left ventricular end-diastolic pressure (9 to 13 mm. Hg). With chloralose-morphine there was a rise in heart rate (84 to 103/min.) and little change in blood pressure (108 to 106 mm. Hg) or left ventricular end-diastolic pressure (6 to 8 mm. Hg). The causes of these differences require further investigation. It is emphasized that when anesthesia cannot be avoided in experimental physiology, the results of the experiment should be carefully reviewed in terms of the anesthetic used.

Hemodynamic effects of acute coronary occlusion

Hemodynamic effects of acute coronary occlusion

Coronary occlusion and embolization: effect on blood flow in adjacent arteries.

ARTICLESCoronary occlusion and embolization: effect on blood flow in adjacent arteriesRM Herzberg, R Rubio, and RM BerneRM Herzberg, R Rubio, and RM BernePublished Online:01 Jan 1966https://doi.org/10.1152/ajplegacy.1966.210.1.169MoreSectionsPDF (1 MB)Download PDF ToolsExport citationAdd to favoritesGet permissionsTrack citations ShareShare onFacebookTwitterLinkedInWeChat Previous Back to Top Next Download PDF FiguresReferencesRelatedInformationCited ByA fresh look at coronary microembolization16 November 2021 | Nature Reviews Cardiology, Vol. 19, No. 4Feasibility and Safety of Low-Dose Intra-Coronary Tenecteplase During Primary Percutaneous Coronary Intervention for ST-Elevation Myocardial Infarction (ICE T-TIMI 49)The American Journal of Cardiology, Vol. 125, No. 4Coronary microembolization and microvascular dysfunctionInternational Journal of Cardiology, Vol. 258Coronary Microembolization and Microvascular Dysfunction *Assessment of the acute effects of glucocorticoid treatment on coronary microembolization using cine, first-pass perfusion, and delayed enhancement MRI11 September 2015 | Journal of Magnetic Resonance Imaging, Vol. 43, No. 4Myocardial Microinfarction after Coronary Microembolization in Swine: MR Imaging CharacterizationRadiology, Vol. 250, No. 3Relation of Hyperemic Epicardial Flow to Outcomes Among Patients With ST-Segment Elevation Myocardial Infarction Receiving Fibrinolytic TherapyThe American Journal of Cardiology, Vol. 101, No. 9Coronary microembolization18 August 2006 | Basic Research in Cardiology, Vol. 101, No. 5N-2-mercaptopropionylglycine, a Scavanger of Reactive Oxygen Species, does not Modify the Early Antiarrhythmic Effect of Ischaemic Preconditioning in Anaesthetised DogsCardiovascular Drugs and Therapy, Vol. 18, No. 6Coronary Microembolization.Circulation Journal, Vol. 67, No. 4Cellular Basis of Physiological and Pathological Myocardial Growth1 January 2011Coronary microembolizationProgress in Cardiovascular Diseases, Vol. 44, No. 3Microembolization in pigs: effects on coronary blood flow and myocardial ischemic toleranceFrank Grund, Hilchen T. Sommerschild, Torstein Lyberg, Knut A. Kirkebøen, and Arnfinn Ilebekk1 August 1999 | American Journal of Physiology-Heart and Circulatory Physiology, Vol. 277, No. 2Digital angiographic impulse response analysis of regional myocardial perfusion. Detection of autoregulatory changes in nonstenotic coronary arteries induced by collateral flow to adjacent stenotic arteries.Circulation, Vol. 89, No. 3Ischemic cardiomyopathy: Pathophysiologic mechanismsProgress in Cardiovascular Diseases, Vol. 33, No. 1Adverse effects of circumflex coronary artery occlusion on blood flow to remote myocardium supplied by a stenosed left anterior descending coronary artery in anesthetized open-chest dogsAmerican Heart Journal, Vol. 113, No. 3Effects of coronary occlusion on flow in the distribution of a neighboring stenotic coronary artery in the dogThe American Journal of Cardiology, Vol. 52, No. 1Coronary hemodynamics during percutaneous transluminal coronary angioplastyThe American Journal of Cardiology, Vol. 49, No. 7Early Arrhythmias and Primary Ventricular Fibrillation after Acute Myocardial Ischaemia in Relation to Pre-existing Coronary CollateralsCholinergic and Purinergic Regulation of Blood Vessels1 January 2011ANGIOGRAPHIC, HISTOMETRIC AND HISTOPATHOLOGICAL STUDIES ON THE INTRAMURAL CORONARY ARTERIES IN THE INFARCTED HEARTPathology International, Vol. 27, No. 4Continuous recording of local myocardial function in normal and ischemic myocardiumBasic Research in Cardiology, Vol. 71, No. 2Expansion of extracellular space in the nonischemic zone of the infarcted heart and concomitant changes in tissue electrolyte contents in the rat.Circulation Research, Vol. 37, No. 6Regulation of coronary blood flowProgress in Cardiovascular Diseases, Vol. 18, No. 2Reflex parasympathetic coronary vasodilation elicited from cardiac receptors in the dog.Circulation Research, Vol. 37, No. 2Experimental myocardial infarctionBasic Research in Cardiology, Vol. 69, No. 2Messung der Kollateraldurchblutung am Hundeherzen mit Hilfe der selektiven Embolisierung eines Coronargef��esPfl�gers Archiv European Journal of Physiology, Vol. 341, No. 3Effect of nitrate infusions on the systemic and coronary circulations following acute experimental myocardial infarction in the intact dogThe American Journal of Cardiology, Vol. 30, No. 4Experimental Occlusion of the Coronary Arteries in the Closed-Chest Dog30 August 2016 | Acta Radiologica. Diagnosis, Vol. 12, No. 5Pathophysiology of ischemic heart diseaseProgress in Cardiovascular Diseases, Vol. 14, No. 3The changes in intramyocardial pressure produced by acute ischemiaThe Journal of Thoracic and Cardiovascular Surgery, Vol. 62, No. 1Coronary MicroembolizationExperimental Myocardial Infarction in the DogCirculation Research, Vol. 25, No. 2Immediate hemodynamic effects of acute coronary occlusion and their modification by anesthesiaThe American Journal of Cardiology, Vol. 22, No. 4Coronary Blood Flow Measurements in the Presence of Arterial ObstructionCirculation Research, Vol. 19, No. 3 More from this issue > Volume 210Issue 1January 1966Pages 169-175 Copyright & PermissionsCopyright © 1966 by American Physiological Societyhttps://doi.org/10.1152/ajplegacy.1966.210.1.169PubMed4955256History Published online 1 January 1966 Published in print 1 January 1966 Metrics

Effects of acute coronary occlusion on performance of right and left ventricles in intact unanesthetized dogs

Changes in the mechanical performance of the right and left ventricles were studied before, during, and after abrupt occlusion of a major coronary artery, by directly recording from indwelling pressure cannulas and flowmeters. Analogue computers were used to derive additional pertinent variables, so that an engineering type of description of ventricular function was inscribed in as many as 22 variables with standard physical units. In 7 of the 9 animals in the series the anterior descending coronary artery was ligated at the time of operation, days or weeks before the experiment. The principal effects of acute occlusion of the left circumflex coronary artery in unanesthetized dogs were a reduction in peak ejection velocity, peak acceleration, and stroke volume of the left ventricle. These changes may be attributed to interference with the left ventricle as an impulse generator, since the pattern of ejection assumed some of the characteristics of the pattern of normal right ventricular outflow. Sustained tachycardia compensated for the reduction in the stroke volume, so that cardiac output was well maintained. The experiments in which large changes in left ventricular performance occurred were suddenly terminated by ventricular fibrillation within minutes or hours of the experimental coronary occlusion.

Effect of acute coronary occlusion upon the movement of Evans blue dye into different areas of pig heart muscle

Because it is rapidly and tenaciously bound to plasma protein, Evans blue dye has found widespread use in the estimation of total body plasma volume by dilution methods. Caster, Simon and Armstrong 1–3 have developed methods for the determination of the Evans blue space in tissue samples, and this has allowed the ready estimation of plasma volumes in each of the tissues of the body. 4 Although there is a slow movement of Evans blue to extravascular positions, kinetic studies suggest that, in large part, this problem can be avoided by injecting the dye no more than 4 to 5 minutes prior to stopping the circulation and removing the tissue samples for analysis. Under these conditions the Evans blue space in a variety of normal rat tissues was found to be quite constant. Hemodynamic alterations caused by gross alteration of the circulating plasma volume or by the injection of large doses of epinephrine resulted in marked changes in the Evans blue space in tissue. 4 The present data relate to an attempt to use this method to study the hemodynamic changes occurring in different portions of the pig heart following coronary occlusion.

Immediate hemodynamic effects of acute coronary artery occlusion.

ArticleImmediate Hemodynamic Effects of Acute Coronary Artery OcclusionRené Wégria, Charles W. Frank, George A. Misrahy, Hsueh-Hwa Wang, Robert Miller, and Robert B. CaseRené WégriaFrom the Department of Medicine, Columbia University College of Physicians and Surgeons, and the Presbyterian Hospital, New York City, Charles W. FrankFrom the Department of Medicine, Columbia University College of Physicians and Surgeons, and the Presbyterian Hospital, New York City, George A. MisrahyFrom the Department of Medicine, Columbia University College of Physicians and Surgeons, and the Presbyterian Hospital, New York City, Hsueh-Hwa WangFrom the Department of Medicine, Columbia University College of Physicians and Surgeons, and the Presbyterian Hospital, New York City, Robert MillerFrom the Department of Medicine, Columbia University College of Physicians and Surgeons, and the Presbyterian Hospital, New York City, and Robert B. CaseFrom the Department of Medicine, Columbia University College of Physicians and Surgeons, and the Presbyterian Hospital, New York CityPublished Online:31 Mar 1954https://doi.org/10.1152/ajplegacy.1954.177.1.123MoreSectionsPDF (874 KB)Download PDF ToolsExport citationAdd to favoritesGet permissionsTrack citations ShareShare onFacebookTwitterLinkedInWeChat Previous Back to Top Next Download PDF FiguresReferencesRelatedInformationCited ByMyocardial Catecholamine Release in Acute Myocardial Ischaemia; Relationship to Cardiac ArrhythmiasContrast VentriculographyDie kontraktile Funktion des �berlebenden Herzmuskels nach Koronarverschlu�Klinische Wochenschrift, Vol. 55, No. 10Circulatory reflexes in myocardial infarction.Heart, Vol. 39, No. 2Attenuation of cardiac sympathetic drive in experimental myocardial ischemia in dogsAmerican Heart Journal, Vol. 93, No. 1Biventricular dynamics during quantitated anteroseptal infarction in the porcine heartThe American Journal of Cardiology, Vol. 36, No. 6Production of Myocardial Infarcts in Animal ExperimentsReflex inhibitory effects of vagal afferents in experimental myocardial infarctionThe American Journal of Cardiology, Vol. 33, No. 7Function of the hypoxic myocardiumThe American Journal of Cardiology, Vol. 32, No. 4Volume Changes of the Left Ventricle during Acute Myocardial Ischaemia in Dogs30 August 2016 | Acta Radiologica. Diagnosis, Vol. 14, No. 5Evidence for a Depressor Reflex Elicited from Left Ventricular Receptors during Occlusion of One Coronary Artery in the CatActa Physiologica Scandinavica, Vol. 88, No. 1Changes in Left Ventricular Performance from Early after Acute Myocardial Infarction to the Convalescent PhaseCirculation, Vol. 46, No. 4Experimental myocardial ischemia and infarctionThe American Journal of Cardiology, Vol. 29, No. 6Left Ventricular Receptors Activated by Severe Asphyxia and by Coronary Artery OcclusionActa Physiologica Scandinavica, Vol. 85, No. 4überlebensquote nach akutem experimentellem Coronarverschluß in Abhängigkeit von Spontankollateralen des HerzensZeitschrift für die gesamte experimentelle Medizin einschließlich experimentelle Chirurgie, Vol. 153, No. 3Immediate hemodynamic effects of acute coronary occlusion and their modification by anesthesiaThe American Journal of Cardiology, Vol. 22, No. 4Cardiovascular alterations during declining and steady-state low cardiac output secondary to coronary insufficiency in the dogThe Journal of Thoracic and Cardiovascular Surgery, Vol. 56, No. 4Effects of interrupted coronary flow upon myocardial metabolism and contractilityProgress in Cardiovascular Diseases, Vol. 10, No. 5SYSTEMIC SHOCK OF CARDIOPULMONARY ORIGINExtracardiac factors contributing to hypotension during coronary occlusionThe American Journal of Cardiology, Vol. 11, No. 2Effects of Selective Coronary Embolization on Coronary Blood Flow and Coronary Sinus Venous Blood Oxygen Saturation in DogsCirculation Research, Vol. 10, No. 5Mechanism of Cardiogenic ShockCirculation Research, Vol. 10, No. 5Untersuchungen zur Pathophysiologie und Therapie des HerzinfarktesArchiv für Kreislaufforschung, Vol. 36, No. 3-4Schock und KollapsDie Coronarerkrankungen. Coronarinsuffizienz, Angina pectoris und HerzinfarktWork capacity of the left ventricle following ligation of the coronary arteryAmerican Heart Journal, Vol. 58, No. 4The mechanism and treatment of shock in acute myocardial infarctionProgress in Cardiovascular Diseases, Vol. 1, No. 2Cardiogenic shockAmerican Heart Journal, Vol. 54, No. 3Durchblutungs�nderungen im Einstromgebiet der Leber bei hypox�mischen MyokardinsuffizienzenPfl�gers Archiv f�r die Gesamte Physiologie des Menschen und der Tiere, Vol. 261, No. 6 More from this issue > Volume 177Issue 1March 1954Pages 123-127 Copyright & PermissionsCopyright © 1954 by American Physiological Societyhttps://doi.org/10.1152/ajplegacy.1954.177.1.123PubMed13148356History Received 30 September 1953 Published online 31 March 1954 Published in print 31 March 1954 Metrics