Retinopathy Edema Research Articles

Review on the Role of Macular Edema in Retinopathy, Blindness and Automated Diagnosis Methods

INTRODUCTION: Macular edema is not a disease itself, but, a very common condition in most of the retinal diseases, such as diabetic retinopathy, retinal vein occlusion, hypertensive retinopathy, age-related macular edema, etc. and post-ocular surgery.OBJECTIVES: We have discussed how macular edema plays an important role in blindness in case of various retinal blood vascular diseases and post-ophthalmic surgery. We have analyzed vast state-of-the-art methods for retinal abnormality detection.METHODS: The proposed method uses a semi-automated macula segmentation approach and Local Binary Pattern features to train k-Nearest Neighbor classifier and performs binary classification.RESULTS: We have achieved 80% accuracy and 90% sensitivity in classifying normal and abnormal retina.CONCLUSION: We justified the notion that it will be beneficial to have a method that can analyse the macula region and alert if there is any abnormality near that region to prevent vision loss.

Error in Figure 4F in: Spectral-Domain Optical Coherence Tomographic Assessment of Severity of Cystoid Macular Edema in Retinopathy of Prematurity

Error in Figure 4F in: Spectral-Domain Optical Coherence Tomographic Assessment of Severity of Cystoid Macular Edema in Retinopathy of Prematurity

Spectral-Domain Optical Coherence Tomographic Assessment of Severity of Cystoid Macular Edema in Retinopathy of Prematurity

To investigate whether the severity of cystoid macular edema (CME) in neonates who were 31 to 36 weeks' postmenstrual age, as viewed by spectral-domain optical coherence tomography (SD-OCT)imaging, predicts the severity of retinopathy of prematurity(ROP) or is related to systemic health. Of 62 prematurely born neonates in a prospective institutional review board-approved study, 42 met the following inclusion criteria: at least 1 SD-OCT imaging session prior to 37 weeks' postmenstrual age and prior to ROP laser treatment, if a laser treatment was performed,and an ophthalmic ROP examination at or after 41 weeks' postmenstrual age, evidence of complete retinal vascularization in zone III, or documentation through telephone report of such information after transfer of care.Measures of CME severity, including central foveal thickness,retinal layer thicknesses, and foveal-to-parafoveal thickness ratio in 1 eye per subject, were compared with ROP outcomes: laser treatment, maximum plus disease,and maximum ROP stage. Systemic health factors were also correlated. Cystoid macular edema was present in 50% of neonates. Multiple elongated cystoid structures within the inner nuclear layer were most common. The presence of CME was not associated with ROP outcomes. The central foveal thickness, the thickness of the inner retinal layers, and the foveal-to-parafoveal thickness ratio were higher in eyes that required laser treatment or that developed plus disease or ROP stage 3. Cystoid macular edema was not clearly associated with systemic factors. Cystoid macular edema is common in premature infants screened for ROP before 37 weeks' postmenstrual age, with the most common SD-OCT phenotype ofa bulging fovea from multiple elongated cystoid spaces. Detection of CME is not associated with ROP severity; however,tomographic thickness measurements could potentially predict a higher risk of requiring laser treatment or developing plus disease or ROP stage 3. Systemic health factors are probably not related to the development of CME.