The Safe and Sustainable by Design (SSbD) concept integrates safety and sustainability of chemicals and materials, throughout their entire life cycle and minimizes their environmental footprint. The European Commission (EC) in 2022 developed a framework to practically apply SSbD. This study investigated the knowledge on SSbD and the operationalization of such framework among the partners of the Partnership for the Assessment of Risks from Chemicals (PARC) program. Forty-one responses from 32 PARC Institutions were collected through a 21 item-online survey. Seventy-three % of the respondents had knowledge of SSbD, although only 49 % reported to have been directly engaged into SSbD projects. The EC-SSbD framework was applied by the 26 % of participants and in 47 % of cases it included a (re)design phase. With respect to the safety and sustainability, the assessment of the hazard, the human health and safety aspects in the production and processing, and the human health and environmental aspects in the final application of the chemical/material was addressed by the 74 %, 52 % and 65 % of the respondents. Lower percentages of positive responses regarded the environmental, social and economic sustainability assessment: 35 %, 20 % and 13 %, respectively. Overall, while the framework provided the necessary building blocks and opportunities for SSbD, concerted and iterative Research, Industry, and Academia efforts are necessary to develop/improve assessment methods, models and tools to make SSbD as an approach to chemical risk assessment and management to protect human health and the environment, and ensure to operate within the planetary boundaries.
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