Eccrine Acrospiroma Research Articles

Sweat gland tumor: A rare diagnosis of eyelid mass- A case report

Eccrine acrospiroma or Nodular hidradenomas are extremely rare sweat gland tumors of eyelid that arise as intradermal nodules from eccrine sweat glands. This case reports documents evaluation of a nodular mass of upper eyelid and its adequate management. Clinical examination followed by wide local excision and histopathologic evaluation of mass was done. Clinically, the mass was diagnosed as sebaceous cell carcinoma of eyelid. Post-operative histopathologic evaluation of the mass was suggestive of benign acrospiroma. Sweat gland tumors constitute of a very small proportion of eyelid tumors which often mimic other malignant tumors of eyelid.

Clinical and morphological features of eccrine acrospiroma: analysis of literature data and case from practice.

Eccrine acrospiroma is a rare benign tumor of the skin arising from the epithelial cells of eccrine sweat ducts. The clinical picture is characterized by its variability, so a detailed morphological study of the operative material is necessary to establish a diagnosis. Differential diagnosis must be carried out with hemangioma, melanoma, infected sebaceous cyst, metastatic skin lesion, and other tumors from elements of the sweat gland. In the article the authors presented the clinical and morphological analysis of own case from practice of large eccrine acrospiroma on the back surface of the left thigh which was diagnosed in a 56-year-old man.

Nodular Swelling with Chronic Discharging Sinus on Leg - An Unusual Presentation of Eccrine Acrospiroma with Cytohistopathological Correlation

Nodular Swelling with Chronic Discharging Sinus on Leg - An Unusual Presentation of Eccrine Acrospiroma with Cytohistopathological Correlation

Eccrine acrospiroma

Eccrine acrospiroma are benign skin tumors of sweat duct origin which are occurring in eyelids. They present as small solid or cystic lesions that are confused clinically with other lesions. This is a case of eccrine acrospiroma with malignant potential of a 90 year-old female with mass over the ventral aspect of the left upper eyelid with bleeding, ulceration, and discharge. This is a rare presentation of histopathological that confirmed eccrine acrospiroma so as to alert the clinician about the differential diagnosis of mass over eye lids. By careful examination, meticulous wide excision and rigorous follow-up potential vision can be restored.

Nodular Hidradenoma: A Forgotten Tumor of the Scalp

Hidradenoma or Eccrine acrospiromas are rare benign tumours that arise from the eccrine sweat gland. Eccrine acrospiromas are nonencapsulated, well-circumscribed, multilobular dermal nodules that may involve the epidermis and extend into the subcutaneous fat. A 30-year-old male patient presented with an asymptomatic progressive swelling on the scalp of 6 months duration. Cutaneous examination: A solitary, non-tender, firm to hard, mobile swelling over the scalp.

Nodular Hidradenoma Mimicking Breast Cancer: Diagnostic Conundrum

A nodular hidradenoma, clear cell hidradenoma or eccrine acrospiroma is an exceedingly rare entity in the breast tissue. It is a benign adnexal cell tumor derived from eccrine sweat gland. To our knowledge approximately thirty cases are reported in English literature. The aim of this article is to raise the awareness of this tumor so that patients can receive appropriate diagnosis and therapy. Herein we report a case of 51-year-old female who underwent complete wide excision of left lateral breast mass. Two years ago the left lateral breast biopsy was diagnosed as an atypical papillary lesion. Essentially, this diagnosis was inconclusive and the breast mass resection followed and the final diagnosis was nodular hidradenoma.

Морфологічні особливості новоутворень ока у собак

Tumors of the eyes in pets are relatively rare. Tumors can adversely affect the functions of the eye, lead to damage to its structures, discoloration, discomfort or changes in the shape of the eyeball. The study of the morphological features of neoplasms of the eye has not only scientific or general biological interest, but also has a purely practical significance.The purpose of our work was to study the frequency of diagnosis, morphological, clinical and macroscopic features of various histological types of eye neoplasms. It was analyzed 178 cases of tumors of different localization in dogs that were admitted to the Department of Pathological Anatomy of the NUP of Ukraine for histological examination from various clinics of veterinary medicine in Kyiv. Neoplasms of the eye were about 3%. The ratio between malignant and benign neoplasms was 1:1. The average age of the sick dogs was 7 years. Most often the eyelids and other parts of the eye's auxiliary apparatus were affected. In only one case, an intraocular tumor was noted. Such statistics are not accurate, as most owners refuse surgical removal of the eyeball. The prevailing clinical form of neoplasm was nodular. Macroscopically, most tumors had a regular oval shape. In one case, an ulcer was found on the surface of the tumor. The melanoma of the uveal tract, the squamous cell carcinoma of the eyelid, the eccrine acrospiroma of the sweat glands of the eyelids, the adenocarcinoma of the sebaceous glands of the eyelids, the hemangioma of the orbit and neurofibroma were diagnosed. Histologically, the neoplasms of the eye did not differ from other similar localizations.The obtained data will supplement the knowledge of researchers of other countries about the histological structure of tumors that are recorded in the eye area, as well as the role of the geographical factor, environmental conditions in the development of oncological pathology.

A Case of Eccrine Acrospiroma With Gastric Metastasis: A Rare Presentation of a Rare Cancer

A Case of Eccrine Acrospiroma With Gastric Metastasis: A Rare Presentation of a Rare Cancer

Göz Kapağında Nodular Hidradenoma

Nodular hidradenoma is a benign cutaneous neoplasm originated from ducts of eccrine sweat glands. It usually presents as slowly enlarging, solitary, freely movable, solid or cystic swelling. İt present most instances measure between 0.5 and 2.0 cm in diameter, although they may be larger. A nodular hidradenoma has ben referred to as a clear cell hidradenoma, an eccrine sweat gland adenoma of the clear cell type, a solid cystic hidradenoma, and an eccrine acrospiroma. We report a case of a nodular hidradenoma in a 23-year-old woman who presented with a nodular swelling in the left lower eyelid. The examination revealed a solitary 6 mmx4 mm sized mass in the lid margin of the left lower eyelid. It was firm to hard in consistency, painless, and did not appear to extend to the deeper underlying tissues. There was no ulceration on the surface. The nodular hidradenoma was diagnosed by excisional biopsy.

Hidradenoma: A Skin Adnexal Tumour, Case Report and Literature Review

Hidradenoma is a cutaneous, often benign tumour of the sweat glands. Also known by various other names such as nodular hidradenoma, eccrine acrospiroma, and solid cystic hidradenoma. A 41 year old man presented with a painless ulcero-proliferative polypoidal swelling over the right lower anterior abdominal wall. Histopathology of the wide local excision of the tumour revealed benign nodular hidradenoma. Benign Nodular Hidradenoma is known by many names such as solid cystic hidradenoma, clear cell myoepithelioma, eccrine sweat gland adenoma, large cell hidradenoma and eccrineacrospiroma. All patients are to be considered potential candidates for curative surgery. The management includes wide local excision with adequate margins to prevent recurrence. It must be differentiated from dermatofibrosarcoma protuberens as management and prognosis differs greatly.

Giant eccrine hidradenoma mimicking a malignant tumor of the salivary gland.

Giant eccrine hidradenoma mimicking a malignant tumor of the salivary gland.

Cytomorphological diagnosis of malignant eccrine tumors: Report of two cases

Though FNAC has been successfully used in diagnosing various neoplastic and nonneoplastic cutaneous lesions, there is a paucity of case reports describing the cytomorphological features of adnexal tumors. We hereby describe the cytological features of two histologically confirmed cases of malignant eccrine tumors. Case number 1 presented with an ulcerated infraclavicular swelling whereas case number 2 presented with a cystic swelling over left foot. FNA and histological examination of the resected specimens was performed using standard techniques. A cytological diagnosis of low grade papillary adenocarcinoma arising from skin adnexal structures was given in case number 1. Aspirate from case number 2 was reported as positive for malignant cells, and histological examination was advised. Histological examination revealed the presence of malignant eccrine acrospiroma in case number 1 and papillary digital adenocarcinoma in case number 2. Careful cytological examination displayed the characteristic of two cell population seen in eccrine tumors in both the cases. Diagnosis of malignant eccrine tumors cannot be made with certainity on cytology alone, hence the need to document the cytological features of these entities is emphasized.

Apocrine hidradenocarcinoma in eyelid with corneal invasion

Abstract Purpose Apocrine hidradenocarcinoma has been named with different terms as apocrine carcinoma, malignant clear cell hidradenoma, nodular hidradenocarcinoma, eccrine acrospiroma, and some others. This wide terminology, together with the rarity of the tumour and variability of the cells that compose it, make it difficult to diagnose. Methods Description of a case. Results 81 years‐old female, with a history of pterygium, subject to enucleation of the eye globe after a preoperative diagnosis of squamous cell carcinoma affecting ocular adnexa, this tumor infiltrated bulbar conjunctiva and cornea. Conclusion Malignant tumours of sweat glands are rare. Among these, hidradenocarcinoma has been described in multiple cutaneous locations and exceptionally in the eye. The frequency is not easy to determine because the terminology that has been used makes difficult to compare the data. In the eye, it may originate from glands of the eyelid or from lacrimal gland. The immunohistochemical study is not important for diagnosis. The neoplastic cells express low molecular weight cytokeratins, and cytokeratin 19. EMA and CEA are expressed in the luminal edge of glandular structures. It is an aggressive tumour, which can widely metastasize and can be cause of death.

Adnexal skin tumors in Zaria, Nigeria

Adnexal skin tumors share many features in common and differentiate along one line. Their detailed morphological classification is difficult because of the variety of tissue elements and patterns seen. They may be clinically confused with other cutaneous tumors. The aim of this report is to review and classify all adnexal tumors seen in a pathology department over a 16-year period. A 16-year retrospective analysis of all adnexal skin tumors seen in a large University Teaching Hospital in Nigeria from January 1991- December 2006. All tissue specimens were fixed in 10% formalin, processed in paraffin wax and stained with Haematoxylin and Eosin. Histology slides were retrieved, studied and lesions characterized. Fifty-two adnexal tumors were seen, accounting for 0.9% of all cutaneous tumors seen within the same period. The median age was 33 years (range: 4 days-70 years). Clinical presentations varied from discreet swellings and nodules to ulcerated masses. Five patients presented with recurrent lesions. Only two cases had a clinical diagnosis of adnexal tumor. Twenty-four (46%) of the lesions were distributed in the head and neck region. Duration of symptoms was 2 months to 15 years (median: 12 months). Tumours of the sweat gland were the commonest--41 (78.8%); they comprised predominantly eccrine acrospiroma (17), characterized histologically by solid nests of round to polygonal cells with clear to eosinophilic cytoplasm, forming tubules in areas. Tumours of sebaceous gland were 7 (13.5%); they comprised mainly Nevus sebaceous of Jadassohn (6), composed of immature sebaceous glands and pilar structures microscopically and a solitary sebaceous adenoma. Tumours of hair follicle were 4 (7.7%) and included trichoepithelioma, characterized microscopically by multiple horn cysts and epithelial tracts connecting abortive pilar structures and a trichofolliculoma. Forty-six lesions (88.5%) were benign and six (11.5%) malignant. Adnexal skin tumors have distinct histological patterns which differentiates them from other cutaneous tumors. They are commonly distributed in the head, neck and trunk. The commonest variants are those of eccrine sweat gland origin. Malignant adnexal tumors are uncommon in our setting.

Eccrine acrospiroma of neck in a 3-year-old female child

Eccrine acrospiroma of neck in a 3-year-old female child

Eccrine acrospiroma of neck in a 3-year-old female child

Eccrine acrospiromas are tumours derived from eccrine sweat gland epithelium. They are usually found in middle-aged people with equal sex predilection. Most of such tumours are found on extremities. We present a case of 3-year-old female child who presented to our institute with a swelling in neck just above the medial end of right clavicle. Thorough clinical, laboratory and radiological investigations were carried out. Taking into consideration the age of the patient and other clinical features a diagnosis of sebaceous cyst of neck was arrived at. The mass was excised under general anaesthesia and sent for histopathological examination. The pathological report established a diagnosis of benign eccrine acrospiroma. The patient has no complaint postoperatively and has been advised to be on regular follow up due to reported cases of recurrence and malignant transformation. Such case of eccrine acrospiroma is rare and has never been reported in the literature and thus should be kept in mind while dealing with neck swellings especially in children taking into consideration its malignant potential.

Eccrine Acrospiroma of Inguinal Area

Eccrine acrospiroma is a tumor originating from the sweat glands. The computed tomography findings of eccrine acrospiroma in the right inguinal area are presented. In our case, the tumor was seen as a well-defined and ovoid-shaped cystic mass with an internal enhancing solid portion and containing calcifications. Eccrine acrospiroma should be considered in the differential diagnosis of a subcutaneous cystic mass with an internal solid nodule.

Eccrine acrospiroma of breast: mammographic and ultrasound findings

There are two types of sweat glands in the human body: eccrine and apocrine. Eccrine glands are the smaller, numerous glands that are diffusely distributed all over the body and are under thermal control. These are most abundant in axillae, palms and soles. Apocrine glands are the larger glands found in axillae, perineum and mammary glands and are the phylogenetic remnant of the mammalian sexual scent glands. Acrospiroma is a benign sweat gland tumour, traditionally classified as a tumour of eccrine gland origin, however, there has been evidence of apocrine origin in some lesions. We present the ultrasound and mammographic findings in a case of eccrine acrospiroma in the axillary tail of the breast in a 77-year-old woman. There have been a few case reports describing the magnetic resonance imaging (MRI) characteristics of this tumour, but there has been no prior description of the ultrasound findings in the literature to the best of our knowledge.

Giant Eccrine Acrospiroma: A Case Report and Review of the Literature

Acrospiromas are histologically distinct cutaneous tumours of sweat duct origin and usually measure 1 to 2 cm in size. We describe a patient with a large benign eccrine acrospiroma. Case report and literature review. A 50-year-old woman underwent excision of a 5.5×5.0 cm cystic mass located on the left gluteal region, and the resulting defect was closed by a local flap. A diagnosis of benign eccrine acrospiroma was made after histopathological examination. On histological examination, the lesion was characterized by multilobular dermal masses composed of a biphasic cell population. There was no recurrence five months after the operation. Although eccrine acrospiromas are usually benign, they can, on rare occasions, undergo malignant transformation. In addition, the clinical appearance of this lesion is not specific and differential diagnosis from other lesions, both benign and malignant, can only be done after the complete removal of the lesion.

Giant eccrine acrospiroma: A case report and review of the literature

Giant eccrine acrospiroma: A case report and review of the literature