EBSCO Information Services Research Articles

The Efficacy of Manual Therapy on Musculoskeletal Pain in Menopause: A Systematic Review.

(1) Background: The aim of this review was to evaluate the effects of manual therapy for musculoskeletal pain in menopausal women. (2) Methods: A comprehensive search of manuscripts published from inception until 29 February 2024 was conducted on PubMed, EBSCO Information Services (EBSCOhost), Physiotherapy Evidence Database (Pedro), Web of Science, Scientific Electronic Library Online (SciELO), Cochrane Central Register of Controlled Clinical Trials, and Scopus using Medical Subject Headings (MeSH) and free terms. Randomized controlled trials (RCT) investigating the effects of manual therapy for musculoskeletal pain in postmenopausal women were included. Articles published in non-English or non-Portuguese languages, case reports, expert opinions, dissertations, conference papers, and gray literature were excluded. Studies were screened for population, musculoskeletal pain, intervention, and pain outcome by two independent reviewers using an ad hoc data extraction form. (3) Results: A total of 5 RCTs (4 with high risk of bias and 1 with low risk of bias) were included (total sample = 245), addressing thumb carpometacarpal osteoarthritis, thoracic kyphosis, chronic neck and backache, knee osteoarthritis, and sternocostal joint pain. The combined results of these studies showed improved musculoskeletal pain in menopausal women; duration of the follow-up was between 4 weeks to 6 months. Conclusions: The majority of studies included in this systematic review were effective in reducing musculoskeletal pain in menopausal women. These results come mainly from studies with a high risk of bias with small sample sizes, and the most representative follow-up period was short-term. Therefore, the results of this systematic review should be interpreted with caution.

Impact of Race, Socioeconomic Status, and Geography on Healthcare Outcomes for Children With Sickle Cell Disease in the United States: A Scoping Review.

A large proportionof patients with sickle cell disease (SCD) identify as Black or African American (AA). Social bias and stigma in healthcare outcomes for children with SCD are impossible to explore without considering the impact of racial/cultural identity, socioeconomic status (SES), and geography. It is important to understand the current influences of social movements, expanded health insurance coverage, and telehealth on these variables when considering healthcare outcomes for patients with SCD. The objective of this study was to determine the roles of racial identity, SES, and geography in healthcare outcomes for the pediatric population of children with SCD in the United States (US). This study is a scoping review following Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. The databases utilized included Cochrane, CINHAL, Medline, and Nursing and Allied Health Collection, all accessed through the EBSCO Information Services. Studies met the following inclusion criteria: published in English, pediatric patients residing in the US, and published between 2017 and 2022. Search terms included "sickle cell" AND "pediatric", which were then combined with "minority" OR "racial" OR "rural" OR "urban" OR "poverty" OR "income" OR "socioeconomic status". The initial search yielded 635 unique articles, with 17 articles meeting full inclusion criteria. Overall, it was clear that there are examples of positive effects of race, low SES, and rural geographic location on positive health outcomes, though a large number of studies oscillated between showing negative associations or no association at all. Barriers to care for patients with SCD are multifaceted, making it difficult to isolate and analyze the impact of individual variables. Many studies demonstrated the significance of family, community, and institutional relationships as positive support for patients with SCD. This review highlights the need for additional research on the healthcare outcome benefits of patient/familial support groups aiming to bring together patients who share racial experience and SCD diagnosis regardless of SES and geography.

Pathways to Research in Business and Economics

Pathways to Research in Business and Economics developed by EBSCO Information Services is part of a suite of subject-specific modules targeted to students starting out in research. The product contains peer-reviewed research summaries by accomplished scholars in their field. Each summary is approximately 3,000 words in length, is written in plain language, includes bibliographies with further reading, and is kept up to date. The summaries are assigned to 19 subjects and cover a wide range in business and economics, with the topics Strategy, Accounting and Finance, and Technology and Innovation the most frequently represented. Users can access the content via the EBSCO Stacks platform, EBSCOhost, or EBSCO Discovery Service.

Examining Physical Wellness as the Fundamental Element for Achieving Holistic Well-Being in Older Persons: Review of Literature and Practical Application in Daily Life.

This review examines the impact of physical activity, nutrition, and sleep evaluations on the physical wellness (PW) and overall well-being of older individuals. A comprehensive search was conducted in databases like PubMed, Google Scholar, and EBSCO Information Services. The search spanned from January 2000 to December 2022, resulting in 19,400 articles, out of which 98 review articles met the inclusion criteria. Through the analysis of these articles, key characteristics of the literature were summarized, and opportunities to enhance the practical application of physical activity (PA), nutrition, and sleep evaluations in the daily lives of older persons were identified. Regular physical activity is crucial for older persons to maintain their physical, mental, and emotional well-being and prevent age-related health issues. Older persons have specific nutritional needs, including increased protein, vitamin D, calcium, and vitamin B12 intake. Poor sleep quality in older persons is associated with negative health outcomes such as cognitive decline, physical disability, and mortality. This review emphasizes the significance of considering physical wellness as a fundamental element for achieving holistic well-being in older persons and highlights the importance of physical activity, nutrition, and sleep evaluations in improving their overall health and well-being. By understanding and implementing these findings, we can enhance the quality of life and promote healthy aging in older persons.

Clinical Outcomes of Anticoagulant Therapy in COVID-19 Patients with Pre-Existing Cardiovascular Diseases: A Systematic Review.

The COVID-19 infection caused by SARS-CoV-2 is a healthcare crisis that has led to unparalleled disruption and has impacted healthcare services, leading to significant morbidity and mortality in the worldwide population. Insufficient data on the management of COVID-19 complications such as hypercoagulability and the controversy about the benefits of anticoagulant therapy are major challenges encountered by clinicians, especially for patients with pre-existing cardiovascular diseases (CVD), and are still debatable. Therefore, we endeavored to conduct a systematic review to assess the clinical outcomes of prior anticoagulant therapy in patients with COVID-19 having pre-existing CVD. Electronic searches of the PubMed database and EBSCO Information Services were carried out, and all relevant articles were employed. Seven articles with data from 21,989 subjects were included. Despite the promised clinical outcomes of anticoagulant therapy, the results of the current systematic review indicated insignificant improvements in the reduction of mortality rate or ICU admission among patients with COVID-19 having pre-existing CVD. Furthermore, direct oral anticoagulant (DOAC) were favored over vitamin K antagonists (VKAs) due to better action and less side effects. In conclusion, the findings are controversial as we did not statistically analyze the results. The data showed inconsistent information with no clear effect of anticoagulant use before patient hospitalization or decreasing COVID-19 severity, particularly in those with CVD. Further studies including randomized controlled trials are required to describe the best course as well as optimal dose of anticoagulant use in the treatment of patients with COVID-19, particularly those with comorbidities such as CVD.

Seven Benefits of Employing Dynamic Health in Clinical Settings

Dynamic Health™, from EBSCO Information Services, is an evidence-based clinical decision support resource designed for quick retrieval of diagnosis and treatment information at the point of patient care.

Updated Evidence in Management of Cleft Lip and Palate: Simple Review Article

The most common oro-facial congenital deformity reported in live newborns is a cleft of the lip, palate, or both. The objective of this study was to the updates in management, and outcomes of cases of cleft lip and/or palate. PubMed and EBSCO Information Services will be chosen as the search databases for the publications used within the study. Topics concerning the updates in management, and outcomes of cases of cleft lip and/or palate, published in English around

Pediatric Fulminant Hepatic Failure: Systematic Review

Abstract: Fulminant hepatic failure FHF in children is a rare but often fatal condition. Our understanding of this disorder is limited due to the disorder's rarity. The majority of FHF cases in children have no known cause. The mechanisms by which hepatocytes undergo cell death are unknown. The aetiology and degree of CNS involvement influence the outcome. The study aims to summarize current evidence on the prevalence, risk factors and management approaches of irritable bowel syndrome in Saudi Arabia. For article selection, the PubMed database and EBSCO Information Services were used. All relevant articles relevant to our topic and other articles were used in our review. Other articles that were not related to this field were excluded. The data was extracted in a specific format that the group members reviewed. Seven studies were included and affirmed that mortality of fulminant hepatic failure is high, and the commonest aetiology is viral infections, particularly HAV. The peak level of total serum bilirubin, the rate of change of the prothrombin time/daily and ammonia level were significant predictors of mortality.

Prevalence and Risk Factors of Migraine in Children, A Systematic Review

Abstract: The most common main headache disease in children and adolescents is migraine. Migraine in children and teenagers is still diagnosed clinically. The doctor requires a thorough headache history that focuses on the kind, location, intensity, and duration of the pain. Most children's migraines are frontal rather than temporal/occipital and bilateral rather than unilateral, which makes them slightly different from adult migraines. Pediatric migraine can be successfully treated with a personalized regimen combining nonpharmacologic and pharmaceutical treatments. Pediatric patients have succeeded with pharmacological treatments for migraine prevention, including beta-blockers, calcium channel antagonists, serotonin antagonists, antidepressants, and antiepileptics. The study summarises current evidence regarding the Prevalence and Risk Factors of Migraine in Children. For article selection, the PubMed database and EBSCO Information Services were used. All relevant articles relevant to our topic and other articles were used in our review. Other articles that were not related to this field were excluded. The data was extracted in a specific format that the group members reviewed. The frequency of family fights and the amount of free time are two important contributors to the emergence of chronic headaches. The way the parents react to their daughter's headaches appears significant for females. Anaemia, obesity, disorders of the abdomen, and early menarche are a few more health issues connected to childhood headaches. Children frequently experience recurrent headaches, which is a serious medical comorbidity. The findings indicated that chronic migraine significantly contributes to headaches in children and adolescents, with various age groups being more concentrated in terms of headache features and risk factors.

Obesity as A Risk Factor for Breast Cancer and Its Prognosis: Systematic Review

Abstract: Obesity is a significant public health issue, particularly in developed countries such as the United States, where more than 36% of adults are obese. Understanding how obesity affects breast cancer is essential for public health because it is the most common cancer and the second leading cause of cancer death among women in developed countries. Numerous studies show a significantly more vital link between increased body mass index (BMI) and breast cancer incidence. Furthermore, obese women with breast cancer have a higher risk of all-cause and breast cancer-specific mortality than non-obese women. A better understanding of the relationship between obesity and breast cancer is critical because this patient population has unique diagnostic and treatment challenges. The study aims to summarize current evidence regarding the association between obesity and breast cancer as a risk factor and its effect on patients' prognosis. For article selection, the PubMed database and EBSCO Information Services were used. All relevant articles relevant to our topic and other articles were used in our review. Other articles that were not related to this field were excluded. The data was extracted in a specific format that the group members reviewed. Our study included nine studies, all of which indicated a positive correlation with different types of breast cancer as a risk factor. One study reported no effect on prognosis.

PREVALENCE AND PREDISPOSITION FACTORS THAT CAUSE CYTOMEGALOVIRUS ESOPHAGITIS

Background: Cytomegalovirus (CMV)-associated gastrointestinal disorders are typically seen in immune-compromised patients; nevertheless, a few cases have been reported in healthy hosts, despite the fact that the pathogenic mechanisms are yet unknown. Various lesions, including erythematous mucosa, erosions, and ulcers, are brought on by CMV esophagitis, albeit these inflammatory alterations can also be seen in nearby or superficial esophageal malignancies. Cancer patients with late and/or terminal stages of the disease have also been known to develop CMV-associated esophagitis due to immunosuppression brought on by chemotherapy or the physiological demands of the cancer itself.
 Objectives: To identify the prevalence of cytomegalovirus esophagitis, describe the evaluation of cytomegalovirus esophagitis and outline the causes of cytomegalovirus esophagitis.
 Methods: For article selection, the PubMed database and EBSCO Information Services were used. All relevant articles relevant with our topic and other articles were used in our review. Other articles that were not related to this field were excluded. The data was extracted in a specific format that was reviewed by the group members.
 Conclusion: Cytomegalovirus (CMV) esophagitis, which can result from illnesses including human immunodeficiency virus (HIV) infection and treatments like post-organ transplantation, long-term dialysis, and systemic steroid therapy, is mostly brought on by systemic immune deficiency. Primary CMV infection, however, can result in serious organ-specific consequences with high morbidity and fatality rates. In immune-competent people, severe CMV infections can have an impact on practically every system.

FLOATING ELBOW: AN INTEGRATIVE LITERATURE REVIEW

Background: Floating elbow is a rare condition caused by ipsilateral humeral and forearm fractures, resulting in an unstable intermediate articulation. High-velocity or high-energy trauma, such as car accidents or high-angle falls, are the main causes of floating elbow injuries. The multiple injuries, open fractures, and neurovascular injury that occur concurrently are the most common. A clinical and radiological diagnosis has been made. Epiphyseal closure and stiffness are problems associated with fractures of the forearm and elbow.
 Objectives: To state the epidemiology of the floating elbow, assess and describe the classification then summarize the management of the injuries of floating elbow.
 Methods: The PubMed database and EBSCO Information Services were utilized to choose the articles. In our review, all pertinent articles related to both our topic and other articles were used. Other articles that have nothing to do with this subject were not included. The group members looked through a certain format in which the data had been extracted.
 Conclusion: Floating elbow is a rare and intricate injury pattern that can result in a variety of functional consequences. The expression describes joint fractures of the humerus and forearm bones in the same extremity. It may affect both adults and children. This damage pattern has been documented in a few published publications, but none of them include epidemiological data, therefore its prevalence remains unknown. Hence, this systemic article state all that helps in knowing the disease.

PREVALENCE AND RISK FACTORS OF BRONCHIAL ASTHMA IN CHILDREN IN SAUDI ARABIA, A SYSTEMATIC REVIEW

Background: The results of the few epidemiological studies that have been carried out in Saudi Arabia to determine the prevalence of childhood asthma are highly inconsistent. As a result, we did a systematic literature review to assess the frequency of childhood asthma in Saudi Arabia since knowing the prevalence of common bronchial asthma in children will help doctors better grasp the scope of this health problem and inform resource planning.
 Objectives: This study aims to summarize current estimations of the prevalence and risk factors of bronchial asthma among children in Saudi Arabia.
 Methods: The PubMed database and EBSCO Information Services were utilised to choose the articles. In our review, all pertinent articles related to both our topic and other articles were used. Other articles that were unrelated to this field were not considered. The data was extracted in a specific format, which the group members reviewed.
 Conclusion: Bronchial asthma prevalence rates in Saudi Arabia are increasing annually. The highest prevalence rate was found in Al Hafouf region while the lowest was reported in Abha. Risk factors were significantly associated with bronchial asthma as phycological status, smoking family member, socioeconomic status, dust, air pollution, allergens as well as other factors.

PREVALENCE OF SICKLE-CELL DISEASE IN SAUDI ARABIA: A SYSTEMATIC REVIEW

Background: A series of hemoglobinopathies known collectively as sickle cell disease (SCD) contain abnormalities in the gene encoding the beta component of haemoglobin. There are other subcategories that fall under the SCD umbrella, including sickle cell disease (SCD), haemoglobin SC disease (HbSC), and haemoglobin sickle-beta thalassemia (beta-thalassemia positive or beta-thalassemia negative). The prevalence of SCD varies greatly across Saudi Arabia, with the Eastern province having the greatest frequency and the southern regions having the second-highest prevalence. The reported sickle-cell prevalence ranges from 2% to 27%, and in some regions, up to 2.6% of people will have SCD.
 Objectives: The study aims to summarize current evidences regarding Prevalence of Sickle-Cell Disease in Saudi Arabia.
 Methods: For article selection, the PubMed database and EBSCO Information Services were used. All relevant articles relevant with our topic and other articles were used in our review. Other articles that were not related to this field were excluded. The data was extracted in a specific format that was reviewed by the group members.
 Conclusion: Although the prevenance of sickle cell anemia is relatively high due to multiple reasons such as consanguinity, the prevalence of genetic diseases in Saudi Arabia may be significantly lowered during the following decades as a result of premarital screening there. Also, acute chest syndrome in SCD patients is relatively infrequent in Saudi Arabia's Eastern Province, it nonetheless has a major impact on morbidity and death. If patients with African haplotypes are compared, it has a low prevalence and recurrence.

HEMORRHOIDECTOMY VERSES RUBBER BAND LIGATION

According to some estimates, haemorrhoids afflict up to one-quarter of all individuals. There are numerous methods available to manage them, ranging from topical and medicinal medicines to outpatient treatments and surgical techniques to repair or excise. Given the disease's polysymptomaticism, determining which therapy choice is optimal is tough. Hemorrhoid disease treatment is one of the most difficult fields in general surgery, with various approaches utilised to cure this illness. In this research, we contrasted Hemorrhoidectomy verses Rubber Band Ligation results of treatment methods for hemorrhoids. Review the effectiveness and safety of the two most often used conventional treatments for haemorrhoids, rubber band ligation and excisional haemorrhoidectomy, and compare between the clinical results for both procedures. The PubMed database and EBSCO Information Services were utilized to choose the articles. In this review, all pertinent articles related to both our topic and other articles were used. Other articles that have nothing to do with this subject were not included. The group members looked through a certain format in which the data had been extracted. Internal hemorrhoid is a common pathological anorectal appearance, although it is a difficult condition to treat. Internal haemorrhoids symptoms and indicators should be thoroughly explored, as should clinical grading. Individual thinking and clinical considerations should influence the various possibilities for managing internal haemorrhoids and specific therapeutic approaches. At first, lifestyle changes should be made, such as consuming a high-fiber diet, developing sane bathroom routines, and administering phlebotropic drugs. When alternative treatments don't work, surgical methods and outpatient procedures should be used. Therapy management such as Hemorrhoidectomy or Rubber Band Ligation is critical to preventing future consequences from internal haemorrhoids.

ANTICOAGULANTS AND THROMBOLYTICS IN PREGNANCY, A SYSTEMATIC REVIEW

Background: In the developed countries, pulmonary thromboembolism associated with pregnancy (VTE) continues to be the principal cause of direct maternal death. Despite thorough treatment and preventative recommendations from several national authorities, reductions in mortality due to VTE have been negligible. Anticoagulation is still the cornerstone of prenatal care and has to be given to all patients with proven or high-risk PE. The preferred medication is low molecular weight heparin (LMWH), which has a known pharmacodynamic profile. Despite the massive utilization of these drugs there is actually little evidence supporting their efficiency in recurrent pregnancy loss reduction.
 Objectives: The study aims to summarize current evidences regarding the usage of anticoagulants and thrombolytics in Pregnancy.
 Methods: For article selection, the PubMed database and EBSCO Information Services were used. All relevant articles relevant with our topic and other articles were used in our review. Other articles that were not related to this field were excluded. The data was extracted in a specific format that was reviewed by the group members.
 Conclusion: A common cause of maternal death, pulmonary embolism-related fatalities still occur often in pregnant women with pulmonary embolism. One-third of pregnant women with pulmonary embolism and hemodynamic failure were reported to undergo systemic thrombolysis. There is an urgent need to improve prevention and care techniques for this vulnerable patient population.
 LMWHs are widely used for several different purposes as well as for the treatment and prevention of VTE during pregnancy and puerperium. Although the medicine has been found to be both safe and effective, there is no scientific proof to support its usage for all indications.
 In pregnant women with thrombophilia who are at high risk of developing these issues, prenatal prophylactic dalteparin does not prevent venous thromboembolism, pregnancy loss, or placenta-mediated pregnancy difficulties and is linked to an increased risk of mild bleeding. Enoxaparin may not offer any meaningful benefits to people suffering from recurrent abortion. However, in one study, the miscarriage rate was significantly lower when enoxaparin was used compared with untreated controls.

Lighting, housing and health: contributions of the 2030 Agenda for sustainable cities and communities

As an important factor in the promotion of environmental comfort, lighting in houses has been increasingly analyzed in studies about health and well-being. Understanding how human exposure to light (artificial or natural) can influence health and the possible beneficial or harmful aspects can contribute to developing strategies that optimize its use and effects, both on human health and on sustainability. Thus, the objectives of this research were to analyze if, and how, lighting in houses can influence human health and determine if the lighting, housing and health topics are connected to the 2030 Agenda Sustainable Development Goals (SDGs). This is a bibliographic review carried out through searches in the Scientific Electronic Library online and EBSCO Information Services databases, based on the following descriptors: lighting, health, housing, environmental comfort and sustainable development, some of their synonyms and in different combinations, researched in Portuguese and English. Other criteria were also used to select the publications to be analyzed, which, in turn, gave rise to two thematic groups: the first addressing environmental comfort in housing, analyzing its relationship with the residents' health and listing important elements for the promotion of environmental comfort; and the second devoted to specifically analyzing the relationship between lighting and human health. When analyzed in an interdisciplinary and intersectoral way, we understand that the “lighting-housing-health” relationship can be connected to the SDGs and effectively contribute to the 2030 Agenda.

Infections after Bone Marrow Transplantation Among Irritable Bowel Syndrome Patients: Review Article

Background: Bone marrow and stem cell transplantation have become conventional therapy, with the potential to cure a variety of hematologic malignancies and immunologic diseases. Severe infection is still a potentially fatal complication following transplantation, contributes significantly to morbidity, and may demand ICU admission. Objectives: The study aims to summarize current evidence on the prevalence, risk factors, and management approaches of irritable bowel syndrome in Saudi Arabia. Methodology: For article selection, the PubMed database and EBSCO Information Services were used. All relevant articles relevant to our topic and other articles were used in our review. Other articles that were not related to this field were excluded. The data was extracted in a specific format that was reviewed by the group members. Conclusion: the result of the 12 studies included, proves the high risk of infections after bone marrow transplantation and its high mortality effect. Post transplantation patient's immune system is vulnerable, opportunistic infections occur such as viruses and fungi. The highest prevalence recorded in Adenovirus infections reaching 29% of patients throat swaps, urine, and stool samples come positive affirming the diagnosis.

Overview on Congestive Heart Failure Imaging

Background: Heart failure is a complex clinical syndrome that results from a functional or structural heart disorder. Acute heart failure is one of the main diagnostic and therapeutic challenges in clinical practice due to a non-specific clinical manifestation and the urgent need for timely and tailored management at the same time. During the first hours of admission the point-of-care focused on cardiac and lung ultrasound examination that are invaluable tool for rapid differential diagnosis of acute dyspnoea, which are highly feasible and relatively easy to learn. Objective: The study aimed to investigate the role of several portable and stationary imaging modalities, which are being increasingly used for the evaluation of cardiac structure and function, haemodynamic and volume status, precipitating myocardial ischaemia or valvular abnormalities, and systemic and pulmonary congestion. Methods: For article selection, the PubMed database and EBSCO Information Services were used. All articles relevant with our topic and other articles were used in our review. Other articles that were not related to this field were excluded. The data was extracted in a specific format that was reviewed by the group members. Conclusion: Heart failure is a main cause of mortality and morbidity worldwide. Assessment of the case is essential to determine the etiology and the best treatment strategy. For the assessment of HF patients, a variety of imaging techniques are used, each with advantages and disadvantages. For its accessibility, affordability, and utility, echocardiography remains the preferred method. It offers the majority of the data necessary it has been improved with the addition of 3DE and strain for the management and follow-up of patients with HF. In particular cases like ischemic heart disease, other methods may be helpful. It should be noted that the right imaging choice can assist in the management of the patient with HF.

The Association Between Post-Traumatic Stress Disorder and Temporomandibular Disorders: A Systematic Review.

The purpose of this systematic study was to discover a connection between temporomandibular joint disorders and post-traumatic stress disorder. A systematic review of observational studies on post-traumatic stress disorder and the incidence of temporomandibular joint disorders (TMD) was conducted. Electronic searches of PubMed, the Saudi Digital Library, Science Direct, the Virtual Health Library (VHL), Scopus, Web of Science, Sage, EBSCO Information Services, and Ovid were performed. There was a consensus among the reviewing examiners. Only studies with the following Medical Subject Headings (MeSH) terms were included: "Posttraumatic stress disorder" combined with "temporomandibular joint disorder," "myofascial pain," "orofacial pain," "internal derangement," "disc displacement with reduction," or "disc displacement without reduction." Only full-text studies in the English language published between 2010 and June 2020 were considered. Of a total of 381 articles meeting the initial screening criteria, only eight were included in the qualitative analysis. Overall, pain is exacerbated in patients with PTSD; that is, their TMD is heightened in all aspects of pain, chronicity, decreased response to conventional therapies, and the need for more potent treatment options as compared with patients with just TMD. The evidence, albeit weak, obtained from the studies included in this review suggests a relationship between PTSD and TMDs.