Emerging data are illuminating the connection between gastrointestinal (GI) conditions such as disorders of gut–brain interaction (DGBI), including irritable bowel syndrome (IBS), celiac disease, and inflammatory bowel disease (IBD) with disordered eating. 1 Singh P. Arora A. Strand T.A. Leffler D.A. Catassi C. Green P.H. et al. Global prevalence of celiac disease: systematic review and meta-analysis. Clin Gastroenterol Hepatol. 2018; 16: 823-836 e2 Abstract Full Text Full Text PDF PubMed Scopus (447) Google Scholar , 2 Houghton LA, Heitkemper M, Crowell M, Emmanuel A, Halpert A, McRoberts JA, et al. Age, gender and women's health and the patient. Gastroenterology. February 15, 2016 [Epub ahead of print]. Google Scholar , 3 Murray H.B. Flanagan R. Banashefski B. Silvernale C.J. Kuo B. Staller K. Frequency of eating disorder pathology among patients with chronic constipation and contribution of gastrointestinal-specific anxiety. Clin Gastroenterol Hepatol. 2020; 18: 2471-2478 Abstract Full Text Full Text PDF PubMed Scopus (11) Google Scholar , 4 Harer K.N. Irritable bowel syndrome, disordered eating, and eating disorders. Gastroenterol Hepatol (N Y). 2019; 15: 280-282 PubMed Google Scholar , 5 Passananti V. Siniscalchi M. Zingone F. Bucci C. Tortora R. Iovino P. et al. Prevalence of eating disorders in adults with celiac disease. Gastroenterol Res Pract. 2013; 2013: 491657 Crossref PubMed Scopus (38) Google Scholar , 6 Hedman A. Breithaupt L. Hubel C. Thornton L.M. Tillander A. Norring C. et al. Bidirectional relationship between eating disorders and autoimmune diseases. J Child Psychol Psychiatry. 2019; 60: 803-812 Crossref PubMed Scopus (36) Google Scholar In turn, eating disorders (EDs), such as anorexia nervosa (AN), bulimia nervosa (BN), and binge eating disorder (BED) can lead to alterations in GI function. 7 Hetterich L. Mack I. Giel K.E. Zipfel S. Stengel A. An update on gastrointestinal disturbances in eating disorders. Mol Cell Endocrinol. 2019; 497: 110318 Crossref PubMed Scopus (24) Google Scholar ,8 Santonicola A. Gagliardi M. Guarino M.P.L. Siniscalchi M. Ciacci C. Iovino P. Eating disorders and gastrointestinal diseases. Nutrients. 2019; 11 Crossref PubMed Scopus (27) Google Scholar In a systematic review of 94 studies with an accurate ED diagnosis, the weighted mean of lifetime ED were 8.4% (range, 3.3% to 18.6%) for women and 2.2% (range, 0.8% to 6.5%) for men. A doubling in prevalence over the study timeline was also noted; the weighted means of point ED prevalence increased from 3.5% for the 2000-2006 period to 7.8% for the 2013-2018 period. 9 Galmiche M. Dechelotte P. Lambert G. Tavolacci M.P. Prevalence of eating disorders over the 2000-2018 period: a systematic literature review. Am J Clin Nutr. 2019; 109: 1402-1413 Crossref PubMed Scopus (246) Google Scholar It is important to interpret prevalence rates for men with caution because they are underrepresented in ED research and less likely to be screened or referred for treatment. 10 Cottrell D.B. Williams J. Eating disorders in men. Nurse Pract. 2016; 41: 49-55 Crossref PubMed Scopus (5) Google Scholar
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