The two Mw > 7.5 earthquakes that struck the East Anatolian Fault (EAF), Türkiye, in 2023 caused more slip than expected, indicating that they were potentially part of a supercycle, in which the occurrence probability of a large earthquake is determined by accumulated strain rather than time since the last large earthquake. Here, we show two potential supercycles along the EAF, analyzing earthquakes from the last two millennia. Within each supercycle, seismic ruptures originated in the northeast and progressively spread southwestward with an increasing number of earthquakes until a new supercycle began with another large earthquake in the northeast. To understand the supercycle behavior, we analyze the aftershock sequences of the four most recent Mw≥6.1 mainshocks (2010–2023). This series of earthquakes progressed southwestward, characterized by an increasing diversity of focal mechanisms and a heightened dispersion of epicenters across a branched seismotectonic environment. Earthquakes in the northeast exhibit spatial and kinematic channeling along the master fault surface, effectively transferring slip southwestward and there potentially triggering dispersed and heterogeneous earthquakes. This spatiotemporal pattern seems connected with varying levels of a presumably-innate property of fault sections or regions, ruling the process of seismic slip channeling, which could also explain the behavior of long-term supercycles.